Arizona Diamondbacks vs Chicago Cubs Prediction & Picks - MLB

USA - MLB

Arizona Diamondbacks
3/28/25 21:40
Chicago Cubs

Prediction:

 

Cubs will win

 

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 by Lou Aguila | in MLB Picks

The Chicago Cubs and the Arizona Diamondbacks resume their season-opening series, with the latter looking to even the score at Chase Field on Friday.

After dropping both games against the LA Dodgers in Japan, the Cubs finally notched their first win of the season at the expense of the Diamondbacks, 10-6. Miguel Amaya chalked up five RBIs behind two doubles to star in the win. The Cubs’ run barrage also helped Justin Steele earn the win still despite allowing three runs in five innings.

Geraldo Perdomo accounted for two of the six runs the D-Backs scored on opening day. Zac Gallen had a disappointing season debut with four runs and four weeks over four innings. Eugenio Suarez delivered the lone homer for Arizona in the game, sending the ball 430 feet from home plate.

Arizona Diamondbacks vs Chicago Cubs Form

Table

Teams Pts P W L
6 Chicago Cubs
0.568 162 92 70
18 Arizona Diamondbacks
0.494 162 80 82

Arizona Diamondbacks and Chicago Cubs Latest Matches

Arizona Diamondbacks
Arizona Diamondbacks Latest matches
L L W W L L
Victories

2/6 (33%)

Defeats

4/6 (67%)

Sep 28, 2024 - MLB

Arizona Diamondbacks
0 :  5
San Diego Padres

Sep 23, 2024 - MLB

Arizona Diamondbacks
3 :  6
San Francisco Giants

Sep 20, 2024 - MLB

Milwaukee Brewers
4 :  7
Arizona Diamondbacks

Sep 15, 2024 - MLB

Arizona Diamondbacks
11 :  10
Milwaukee Brewers

Sep 6, 2024 - MLB

Houston Astros
8 :  0
Arizona Diamondbacks

Sep 5, 2024 - MLB

San Francisco Giants
3 :  2
Arizona Diamondbacks
L W L W L L
Victories

2/6 (33%)

Defeats

4/6 (67%)

Sep 28, 2024 - MLB

Arizona Diamondbacks
0 :  5
San Diego Padres

Sep 23, 2024 - MLB

Arizona Diamondbacks
3 :  6
San Francisco Giants

Sep 15, 2024 - MLB

Arizona Diamondbacks
11 :  10
Milwaukee Brewers

Sep 2, 2024 - MLB

Arizona Diamondbacks
6 :  11
Los Angeles Dodgers

Sep 1, 2024 - MLB

Arizona Diamondbacks
14 :  3
Los Angeles Dodgers

Aug 31, 2024 - MLB

Arizona Diamondbacks
6 :  8
Los Angeles Dodgers
W W W L L W
Victories

4/6 (67%)

Defeats

2/6 (33%)

Sep 20, 2024 - MLB

Milwaukee Brewers
4 :  7
Arizona Diamondbacks

Sep 6, 2024 - MLB

Houston Astros
8 :  0
Arizona Diamondbacks

Sep 5, 2024 - MLB

San Francisco Giants
3 :  2
Arizona Diamondbacks

Sep 3, 2024 - MLB

San Francisco Giants
7 :  8
Arizona Diamondbacks

Aug 25, 2024 - MLB

Boston Red Sox
5 :  7
Arizona Diamondbacks

Aug 21, 2024 - MLB

Miami Marlins
8 :  10
Arizona Diamondbacks
Chicago Cubs
Chicago Cubs Latest matches
W L W L L L
Victories

2/6 (33%)

Defeats

4/6 (67%)

Mar 19, 2025 - MLB

Chicago Cubs
3 :  6
Los Angeles Dodgers

Mar 18, 2025 - MLB

Chicago Cubs
1 :  4
Los Angeles Dodgers

Sep 25, 2024 - MLB

Philadelphia Phillies
9 :  6
Chicago Cubs

Sep 24, 2024 - MLB

Philadelphia Phillies
4 :  10
Chicago Cubs

Sep 21, 2024 - MLB

Chicago Cubs
1 :  5
Washington Nationals

Sep 19, 2024 - MLB

Chicago Cubs
7 :  6
Washington Nationals
L W W L L L
Victories

2/6 (33%)

Defeats

4/6 (67%)

Mar 19, 2025 - MLB

Chicago Cubs
3 :  6
Los Angeles Dodgers

Mar 18, 2025 - MLB

Chicago Cubs
1 :  4
Los Angeles Dodgers

Sep 21, 2024 - MLB

Chicago Cubs
1 :  5
Washington Nationals

Sep 19, 2024 - MLB

Chicago Cubs
7 :  6
Washington Nationals

Sep 8, 2024 - MLB

Chicago Cubs
2 :  1
New York Yankees

Sep 7, 2024 - MLB

Chicago Cubs
0 :  2
New York Yankees
W W L L W L
Victories

3/6 (50%)

Defeats

3/6 (50%)

Sep 25, 2024 - MLB

Philadelphia Phillies
9 :  6
Chicago Cubs

Sep 24, 2024 - MLB

Philadelphia Phillies
4 :  10
Chicago Cubs

Sep 14, 2024 - MLB

Colorado Rockies
6 :  5
Chicago Cubs

Sep 11, 2024 - MLB

Los Angeles Dodgers
10 :  8
Chicago Cubs

Sep 9, 2024 - MLB

Los Angeles Dodgers
4 :  10
Chicago Cubs

Aug 28, 2024 - MLB

Pittsburgh Pirates
10 :  14
Chicago Cubs

Arizona Diamondbacks against Chicago Cubs : Head to Head (H2H)

Arizona Diamondbacks

67 %

Chicago Cubs

33 %

Jul 20, 2024 - MLB

Chicago Cubs
0 :  3
Arizona Diamondbacks

Jul 19, 2024 - MLB

Chicago Cubs
2 :  5
Arizona Diamondbacks

Apr 15, 2024 - MLB

Arizona Diamondbacks
2 :  3
Chicago Cubs

Arizona Diamondbacks - Chicago Cubs Key Points

  1. Chicago Cubs are 6-12 SU in their last 18 games against Arizona.
  2. Chicago Cubs are 3-6 SU in their last 9 games played in March.
  3. Arizona are 2-6 SU in their last 8 games.
  4. Arizona are 2-5 SU in their last 7 games at home.

Our Arizona Diamondbacks vs Chicago Cubs Prediction

Jameson Taillon will start for the Cubs, who are still my pick to win and cover on Friday. Taillon will be pitching against the Diamondbacks for the first time since blanking them through six innings on September 8, 2023. Chicago has already tallied 14 runs in three games while batting .219. D-Backs starter Merrill Kelly, who finished with a 4.42 ERA last season, faces enormous pressure to neutralize the Cubs offense, which produced 10 runs the other day. While I doubt Chicago can top their offensive explosion in Game 1, they will still score plenty of runs in this game too to outgun the Diamondbacks the second time. Our betting prediction for Chicago Cubs vs. Arizona Diamondbacks: Cubs will win.

Prediction:

 

Cubs will win

 

All tips are fully researched and given in good faith, but profits cannot be guaranteed.

Arizona Diamondbacks vs Chicago Cubs Picks