Buffalo Sabres vs Chicago Blackhawks Prediction & Picks - NHL

USA - NHL

Buffalo Sabres
11/21/25 19:00
Chicago Blackhawks

Prediction:

 

Blackhawks to win

+155
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 by Taavi Pailk | in NHL Picks

In an NHL inter-conference matchup, the Buffalo Sabres welcome the Chicago Blackhawks to the KeyBank Center on Friday.

The Sabres enter the action as the last-placed team in the Eastern Conference. Lindy Ruff's men hold the fifth-worst defensive record in the NHL, and the offense hasn't been good enough to deliver the team victories on a consistent basis.

On Wednesday, the Sabres were unable to record their first three-game winning streak of the season, suffering a 6-2 home loss to the Calgary Flames. The team erased a 2-0 deficit in the second period but allowed four goals in the final frame.

The Blackhawks beat the Flames on Tuesday to improve to 10-5-4. They enter Thursday's matchup against the Seattle Kraken with a 5-0-1 run over their last six contests. Playing on consecutive nights is always challenging for teams, but Jeff Blashill's squad currently has good momentum that should help them manage any fatigue.

Chicago has been very impressive this season, holding the fourth-best defensive record in the league and averaging the fifth-most goals. Their young star Connor Bedard has been exceptional lately, notching 10 goals and 11 assists over the past 10 games.

Buffalo Sabres vs Chicago Blackhawks Form

Table

Teams Pts P W L GD
4 Buffalo Sabres
109 2122 42 23 +47
31 Chicago Blackhawks
72 1867 22 39 -62

Buffalo Sabres and Chicago Blackhawks Latest Matches

Buffalo Sabres
Buffalo Sabres Latest matches
L L W W L W
Victories

3/6 (50%)

Defeats

3/6 (50%)

Nov 21, 2025 - NHL

Buffalo Sabres
9 :  3
Chicago Blackhawks

Nov 19, 2025 - NHL

Buffalo Sabres
2 :  6
Calgary Flames

Nov 17, 2025 - NHL

Buffalo Sabres
5 :  1
Edmonton Oilers

Nov 15, 2025 - NHL

Detroit Red Wings
4 :  5
Buffalo Sabres

Nov 13, 2025 - NHL

Colorado Avalanche
6 :  3
Buffalo Sabres

Nov 12, 2025 - NHL

Utah Mammoth
5 :  2
Buffalo Sabres
W L L W L W
Victories

3/6 (50%)

Defeats

3/6 (50%)

Nov 21, 2025 - NHL

Buffalo Sabres
9 :  3
Chicago Blackhawks

Nov 19, 2025 - NHL

Buffalo Sabres
2 :  6
Calgary Flames

Nov 17, 2025 - NHL

Buffalo Sabres
5 :  1
Edmonton Oilers

Nov 6, 2025 - NHL

Buffalo Sabres
0 :  3
St. Louis Blues

Nov 4, 2025 - NHL

Buffalo Sabres
1 :  2
Utah Mammoth

Nov 1, 2025 - NHL

Buffalo Sabres
4 :  3
Washington Capitals
L L L L L W
Victories

1/6 (17%)

Defeats

5/6 (83%)

Nov 15, 2025 - NHL

Detroit Red Wings
4 :  5
Buffalo Sabres

Nov 13, 2025 - NHL

Colorado Avalanche
6 :  3
Buffalo Sabres

Nov 12, 2025 - NHL

Utah Mammoth
5 :  2
Buffalo Sabres

Nov 8, 2025 - NHL

Carolina Hurricanes
6 :  3
Buffalo Sabres

Oct 30, 2025 - NHL

Boston Bruins
4 :  3
Buffalo Sabres

Oct 25, 2025 - NHL

Toronto Maple Leafs
4 :  3
Buffalo Sabres
Chicago Blackhawks
Chicago Blackhawks Latest matches
W L W W L L
Victories

3/6 (50%)

Defeats

3/6 (50%)

Nov 21, 2025 - NHL

Buffalo Sabres
9 :  3
Chicago Blackhawks

Nov 20, 2025 - NHL

Chicago Blackhawks
2 :  3
Seattle Kraken

Nov 18, 2025 - NHL

Chicago Blackhawks
5 :  2
Calgary Flames

Nov 15, 2025 - NHL

Chicago Blackhawks
3 :  2
Toronto Maple Leafs

Nov 12, 2025 - NHL

Chicago Blackhawks
3 :  4
New Jersey Devils

Nov 9, 2025 - NHL

Detroit Red Wings
1 :  5
Chicago Blackhawks
L W L W W L
Victories

3/6 (50%)

Defeats

3/6 (50%)

Nov 20, 2025 - NHL

Chicago Blackhawks
2 :  3
Seattle Kraken

Nov 18, 2025 - NHL

Chicago Blackhawks
5 :  2
Calgary Flames

Nov 15, 2025 - NHL

Chicago Blackhawks
3 :  2
Toronto Maple Leafs

Nov 12, 2025 - NHL

Chicago Blackhawks
3 :  4
New Jersey Devils

Oct 28, 2025 - NHL

Chicago Blackhawks
7 :  3
Ottawa Senators

Oct 26, 2025 - NHL

Chicago Blackhawks
1 :  3
Los Angeles Kings
L L W W W L
Victories

3/6 (50%)

Defeats

3/6 (50%)

Nov 21, 2025 - NHL

Buffalo Sabres
9 :  3
Chicago Blackhawks

Nov 9, 2025 - NHL

Detroit Red Wings
1 :  5
Chicago Blackhawks

Nov 7, 2025 - NHL

Calgary Flames
0 :  4
Chicago Blackhawks

Nov 5, 2025 - NHL

Vancouver Canucks
2 :  5
Chicago Blackhawks

Nov 3, 2025 - NHL

Seattle Kraken
3 :  1
Chicago Blackhawks

Nov 1, 2025 - NHL

Edmonton Oilers
3 :  2
Chicago Blackhawks

Buffalo Sabres against Chicago Blackhawks : Head to Head (H2H)

Buffalo Sabres

50 %

Chicago Blackhawks

50 %

Nov 21, 2025 - NHL

Buffalo Sabres
9 :  3
Chicago Blackhawks

Dec 8, 2017 - NHL

Chicago Blackhawks
3 :  2
Buffalo Sabres
Buffalo Sabres vs Chicago Blackhawks Picks

Players list

Buffalo Sabres
Buffalo Sabres

A. Lyon

U. Luukkonen

O. Power

B. Byram

M. Samuelsson

J. Bryson

C. Timmins

R. Dahlin

J. Quinn

I. Rosen

P. Krebs

N. Ostlund

T. Kozak

J. Doan

T. Thompson

A. Tuch

J. Zucker

B. Malenstyn

R. McLeod

J. Greenway

Chicago Blackhawks
Chicago Blackhawks

S. Knight

A. Soderblom

L. Crevier

A. Vlasic

W. Kaiser

S. Rinzel

M. Grzelcyk

C. Murphy

A. Levshunov

T. Teravainen

L. Slaggert

C. Dach

O. Moore

R. Greene

C. Bedard

F. Nazar

T. Bertuzzi

I. Mikheyev

S. Lafferty

R. Donato

Most goals and assists

CD Huachipato Buffalo Sabres
CD Huachipato Chicago Blackhawks
Top Goalscorer
USA T. Thompson (45 Goals)
Top Goalscorer
Canada T. Bertuzzi (32 Goals)
Best assists
Sweden R. Dahlin (65 Assists)
Best assists

Buffalo Sabres - Chicago Blackhawks Key Points

  1. Buffalo has beaten Chicago in four consecutive regular-season meetings.
  2. The Sabres have a 6-4-2 record at home this season.
  3. The Blackhawks have gone 5-3-2 on the road, winning each of their last three away games.
  4. Buffalo has killed off a league-best 89.9 percent of penalties, while Chicago is ranked at sixth at 84.3 percent.

Our Buffalo Sabres vs Chicago Blackhawks Prediction

The Sabres recently managed to defeat Detroit and Edmonton in back-to-back games, but the team is giving up a lot of goals, which makes it extremely difficult to climb out from the bottom of the Eastern Conference.

After opening the season with three consecutive losses, the Blackhawks have suffered only a handful of regulation defeats. They have played high-level hockey on both ends of the ice and look ready to end a five-year postseason drought. In contrast, Buffalo appears very far from breaking its run of 14 consecutive seasons without a playoff appearance.

Our prediction for Chicago Blackhawks vs. Buffalo Sabres: Blackhawks to win.

Prediction:

 

Blackhawks to win

+155
$1000 offered for betting!

All tips are fully researched and given in good faith, but profits cannot be guaranteed.