New England Patriots vs Buffalo Bills Prediction & Picks - NFL
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by Carlos Zabala | in NFL Picks
The Bills managed to defeat the Bengals in a thrilling game last week, securing their ninth win of the season. The Bills secured their ninth win of the season by defeating the Bengals by a score of 39-34 in a snowy Highmark Stadium; Buffalo secured the victory in the final moments with a play that garnered significant attention. Brentford, in an impractical fashion, intercepted Burrow's soft pass and executed a 63-yard pick-6. Josh Allen had an outstanding day, throwing three touchdown passes for the Bills and running for another for himself.
In the NFL Week 15 betting odds, there's no matchup closer than the Bills-Patriots. The 11-2 Pats are slight underdogs at Gillette Stadium; a win for New England would clinch their first division title of the decade.
The formidable Patriots have won each of their last 10 games, had a bye last week, and then defeated the Giants 33-15 in Week 13.
Drake Maye, the New England quarterback, continues to have an epic season. Against the Giants, he completed 24 of 31 passes for 282 yards and two touchdowns.
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New England Patriots vs Buffalo Bills Form
Table
| Teams | Pts | P | W | L |
|---|---|---|---|---|
|
3
|
0.824 | 17 | 14 | 3 |
|
8
|
0.706 | 17 | 12 | 5 |
New England Patriots and Buffalo Bills Latest Matches
6/6 (100%)
0/6 (0%)
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5/6 (83%)
1/6 (17%)
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6/6 (100%)
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4/6 (67%)
2/6 (33%)
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5/6 (83%)
1/6 (17%)
Dec 7, 2025 - NFL
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3/6 (50%)
3/6 (50%)
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New England Patriots against Buffalo Bills : Head to Head (H2H)
60 %
40 %
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Dec 31, 2023 - NFL
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New England Patriots - Buffalo Bills Key Points
- The Bills are second in the NFL in total yards with 399.1
- The Bills lead the NFL in rushing yards per game with 157.8
- The Patriots have the sixth-best defense in terms of total yards allowed per game
- Buffalo are 3-3 on the road this season
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Our New England Patriots vs Buffalo Bills Prediction
Maye's elite season has Pats fans buzzing. Comparisons to Brady are inevitable, especially since he has completed over 70% of his passes this season. He is on track to surpass the franchise record Brady set in 2007 with 68.9%.
Despite interceptions 10 times this season, Josh Allen is enjoying a very respectable season with the Bills. Therefore, a high-scoring match seems likely.
Our predictions for Bills vs Patriots are: Over 248.5.
All tips are fully researched and given in good faith, but profits cannot be guaranteed.