Toronto Blue Jays vs Boston Red Sox Prediction & Picks - MLB

Prediction published on 4/30/25, 3:59 PM  by Carlos Zabala | Modified on 2/11/26 at 8:35 AM in MLB Picks

The Red Sox bats are hot to close out April. They've scored seven or more runs in their last three games and 10 or more in their last two. Against the Blue Jays at Rogers Centre, it was all smiles with home runs from Durant, Bregman, Devers, Campbell, and Abreu, bringing their record to 17-14.

Also, on the pitching side, Crochet continues to add merit, and a long-term competition between him and Skubal for this season's Cy Young Award is looming. The Blue Jays had no answers against Crochet on a night in which Toronto only managed four hits, but on a positive note, one of those hits was Vlad Jr.'s third home run of the season.

At -135 odds on the road, the Red Sox won that first game against the Blue Jays. At odds around -120, they will be favorites on Wednesday. The Red Sox's betting record as the away favorites is 5-4, while the Blue Jays' record as the underdogs at home is 3-4.

Giolito is set to make his Red Sox debut on Wednesday. He's the tentative starter for Game 2. He didn't do very well in his rehab outings, but he said they were focusing more on his mechanics than on getting outs in his rehab games.