St. Louis Cardinals vs Boston Red Sox Prediction & Picks - MLB

USA - MLB

St. Louis Cardinals
4/11/26 19:15
Boston Red Sox

Prediction:

 

The Red Sox -1.5 Runs

+118
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 by Lou Aguila | in MLB Picks

Undefeated in their last four matches against the St. Louis Cardinals, the Boston Red Sox look to maintain their mastery over the NL team in Game 2 on Saturday.

Momentum: The Red Sox won the last two games of their series against the Milwaukee Brewers. Meanwhile, the St. Louis Cardinals have won 3 of their last four games, including back-to-back wins over the Washington Nationals.

Matchup: The Red Sox and the Cardinals will be playing in their intra-league series. Game 2 starters will be the Red Sox’s left-handed pitcher Ranger Suarez (0-1, 8.64 ERA) and the Cardinals' right-handed pitcher Kyle Leahy (1-1, 5.40 ERA).

Hot on the Board: The Red Sox are -135 favorites with Suarez starting and +118 to cover -1.5 runs. The Cardinals are +115 home underdogs mainly because they have lost their last four games to the Red Sox.

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St. Louis Cardinals vs Boston Red Sox Form

Table

Teams Pts P W L
7 Boston Red Sox
0.542 118 64 54
14 St. Louis Cardinals
0.5 118 59 59

St. Louis Cardinals and Boston Red Sox Latest Matches

St. Louis Cardinals
St. Louis Cardinals Latest matches
L L W L W W
Victories

3/6 (50%)

Defeats

3/6 (50%)

Apr 8, 2026 - MLB

Washington Nationals
1 :  6
St. Louis Cardinals

Apr 7, 2026 - MLB

Washington Nationals
6 :  7
St. Louis Cardinals

Apr 6, 2026 - MLB

Washington Nationals
9 :  6
St. Louis Cardinals

Apr 5, 2026 - MLB

Detroit Tigers
3 :  5
St. Louis Cardinals

Apr 4, 2026 - MLB

Detroit Tigers
11 :  6
St. Louis Cardinals

Apr 3, 2026 - MLB

Detroit Tigers
4 :  0
St. Louis Cardinals
W W L L W W
Victories

4/6 (67%)

Defeats

2/6 (33%)

Apr 1, 2026 - MLB

St. Louis Cardinals
2 :  1
New York Mets

Mar 31, 2026 - MLB

St. Louis Cardinals
3 :  0
New York Mets

Mar 30, 2026 - MLB

St. Louis Cardinals
2 :  4
New York Mets

Mar 29, 2026 - MLB

St. Louis Cardinals
7 :  11
Tampa Bay Rays

Mar 28, 2026 - MLB

St. Louis Cardinals
6 :  5
Tampa Bay Rays

Mar 26, 2026 - MLB

St. Louis Cardinals
9 :  7
Tampa Bay Rays
L L W L W W
Victories

3/6 (50%)

Defeats

3/6 (50%)

Apr 8, 2026 - MLB

Washington Nationals
1 :  6
St. Louis Cardinals

Apr 7, 2026 - MLB

Washington Nationals
6 :  7
St. Louis Cardinals

Apr 6, 2026 - MLB

Washington Nationals
9 :  6
St. Louis Cardinals

Apr 5, 2026 - MLB

Detroit Tigers
3 :  5
St. Louis Cardinals

Apr 4, 2026 - MLB

Detroit Tigers
11 :  6
St. Louis Cardinals

Apr 3, 2026 - MLB

Detroit Tigers
4 :  0
St. Louis Cardinals
Boston Red Sox
Boston Red Sox Latest matches
W L L L W W
Victories

3/6 (50%)

Defeats

3/6 (50%)

Apr 8, 2026 - MLB

Boston Red Sox
5 :  0
Milwaukee Brewers

Apr 7, 2026 - MLB

Boston Red Sox
3 :  2
Milwaukee Brewers

Apr 6, 2026 - MLB

Boston Red Sox
6 :  8
Milwaukee Brewers

Apr 5, 2026 - MLB

Boston Red Sox
6 :  8
San Diego Padres

Apr 4, 2026 - MLB

Boston Red Sox
2 :  3
San Diego Padres

Apr 3, 2026 - MLB

Boston Red Sox
5 :  2
San Diego Padres
W L L L W W
Victories

3/6 (50%)

Defeats

3/6 (50%)

Apr 8, 2026 - MLB

Boston Red Sox
5 :  0
Milwaukee Brewers

Apr 7, 2026 - MLB

Boston Red Sox
3 :  2
Milwaukee Brewers

Apr 6, 2026 - MLB

Boston Red Sox
6 :  8
Milwaukee Brewers

Apr 5, 2026 - MLB

Boston Red Sox
6 :  8
San Diego Padres

Apr 4, 2026 - MLB

Boston Red Sox
2 :  3
San Diego Padres

Apr 3, 2026 - MLB

Boston Red Sox
5 :  2
San Diego Padres
W L L L L L
Victories

1/6 (17%)

Defeats

5/6 (83%)

Apr 1, 2026 - MLB

Houston Astros
6 :  4
Boston Red Sox

Mar 31, 2026 - MLB

Houston Astros
9 :  2
Boston Red Sox

Mar 30, 2026 - MLB

Houston Astros
8 :  1
Boston Red Sox

Mar 29, 2026 - MLB

Cincinnati Reds
3 :  2
Boston Red Sox

Mar 28, 2026 - MLB

Cincinnati Reds
6 :  5
Boston Red Sox

Mar 26, 2026 - MLB

Cincinnati Reds
0 :  3
Boston Red Sox

St. Louis Cardinals against Boston Red Sox : Head to Head (H2H)

St. Louis Cardinals

25 %

Boston Red Sox

75 %

Apr 6, 2025 - MLB

Boston Red Sox
18 :  7
St. Louis Cardinals

Apr 4, 2025 - MLB

Boston Red Sox
13 :  9
St. Louis Cardinals

May 19, 2024 - MLB

St. Louis Cardinals
3 :  11
Boston Red Sox

Mar 12, 2024 - MLB Spring Training

Boston Red Sox
6 :  8
St. Louis Cardinals
St. Louis Cardinals vs Boston Red Sox Picks

St. Louis Cardinals - Boston Red Sox Key Points

  1. Boston is 4-1 SU in its last 5 games against St. Louis.
  2. Boston is 3-8 SU in its last 11 games.
  3. St. Louis is 6-12 SU in its last 18 games against an opponent in the American League.
  4. St. Louis is 5-2 SU in its last 7 games at home.
Up to $250 to bet on St. Louis Cardinals - Boston Red Sox! 

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Our St. Louis Cardinals vs Boston Red Sox Prediction

Fearless Forecast: The Red Sox nip the Cardinals

Best Pick: The Red Sox -1.5 Runs

I am counting on the Red Sox lefty Ranger Suarez to dominate the Cardinals. Suarez had a disappointing debut with four runs allowed in 4.1 innings pitched in a 1-8 loss to Houston, but I feel the ace pitcher will be back with a vengeance in his second start this season. Leahy (0-2, 4.50 ERA) is still untested against the Cardinals, which could put him in a lot of trouble if they find their range. Leahy allowed four earned runs over five innings in a 2-4 loss to the New York Mets on March 30.

Our betting prediction for the Boston Red Sox vs. St. Louis Cardinals: The Red Sox -1.5 Runs

Prediction:

 

The Red Sox -1.5 Runs

+118
$250 offered for betting!

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