Philadelphia Phillies vs Boston Red Sox Prediction & Picks - MLB

USA - MLB

Philadelphia Phillies
7/21/25 18:45
Boston Red Sox

Prediction:

 

Phillies -2.5

+144
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 by Travis Pulver | in MLB Picks

The Phillies will host the Boston Red Sox at Citizens Bank Park in Philadelphia in a three-game series. Game One of this series is scheduled for 6:45 p.m. EST.

Both teams got the second half of the season off to a rough start, losing two of three games over the weekend. Boston dropped the first two vs. the Cubs in Chicago, 4-12 and 6-1. But the offense came alive in the series finale, and they won the finale, 6-1. Philadelphia lost its opener vs. the Los Angeles Angels 6-5 but bounced back and won the second 9-5, but lost the series finale Sunday 8-2. The Red Sox have Walker Buehler scheduled to start. Buehler has gone 6-6 in 16 starts with a 6.12 ERA, 1.56 WHIP, and .282 OBA. He has had a hard time on the road this season, going 3-4 in eight starts with an 8.66 ERA and .342 OBA. Philadelphia is scheduled to start Zack Wheeler. Wheeler is 9-3 in 19 starts with a 2.36 ERA, .86 WHIP, and .181 OBA. He has been at his best at home, where he is 6-1 in ten starts with a 1.91 ERA and .164 OBA.

Philadelphia Phillies vs Boston Red Sox Form

Table

Teams Pts P W L
2 Philadelphia Phillies
0.593 162 96 66
9 Boston Red Sox
0.549 162 89 73

Philadelphia Phillies and Boston Red Sox Latest Matches

Philadelphia Phillies
Philadelphia Phillies Latest matches
L L W L W L
Victories

2/6 (33%)

Defeats

4/6 (67%)

Jul 20, 2025 - MLB

Philadelphia Phillies
2 :  8
Los Angeles Angels

Jul 19, 2025 - MLB

Philadelphia Phillies
9 :  5
Los Angeles Angels

Jul 18, 2025 - MLB

Philadelphia Phillies
5 :  6
Los Angeles Angels

Jul 13, 2025 - MLB

San Diego Padres
1 :  2
Philadelphia Phillies

Jul 12, 2025 - MLB

San Diego Padres
5 :  4
Philadelphia Phillies

Jul 11, 2025 - MLB

San Diego Padres
4 :  2
Philadelphia Phillies
L W W L W L
Victories

3/6 (50%)

Defeats

3/6 (50%)

Jul 20, 2025 - MLB

Philadelphia Phillies
2 :  8
Los Angeles Angels

Jul 19, 2025 - MLB

Philadelphia Phillies
9 :  5
Los Angeles Angels

Jul 18, 2025 - MLB

Philadelphia Phillies
5 :  6
Los Angeles Angels

Jul 6, 2025 - MLB

Philadelphia Phillies
3 :  1
Cincinnati Reds

Jul 5, 2025 - MLB

Philadelphia Phillies
5 :  1
Cincinnati Reds

Jul 4, 2025 - MLB

Philadelphia Phillies
6 :  9
Cincinnati Reds
L L W L L W
Victories

2/6 (33%)

Defeats

4/6 (67%)

Jul 13, 2025 - MLB

San Diego Padres
1 :  2
Philadelphia Phillies

Jul 12, 2025 - MLB

San Diego Padres
5 :  4
Philadelphia Phillies

Jul 11, 2025 - MLB

San Diego Padres
4 :  2
Philadelphia Phillies

Jul 9, 2025 - MLB

San Francisco Giants
0 :  13
Philadelphia Phillies

Jul 8, 2025 - MLB

San Francisco Giants
4 :  3
Philadelphia Phillies

Jul 7, 2025 - MLB

San Francisco Giants
3 :  1
Philadelphia Phillies
Boston Red Sox
Boston Red Sox Latest matches
W W W L L W
Victories

4/6 (67%)

Defeats

2/6 (33%)

Jul 20, 2025 - MLB

Chicago Cubs
1 :  6
Boston Red Sox

Jul 19, 2025 - MLB

Chicago Cubs
6 :  0
Boston Red Sox

Jul 18, 2025 - MLB

Chicago Cubs
4 :  1
Boston Red Sox

Jul 13, 2025 - MLB

Boston Red Sox
4 :  1
Tampa Bay Rays

Jul 12, 2025 - MLB

Boston Red Sox
1 :  0
Tampa Bay Rays

Jul 11, 2025 - MLB

Boston Red Sox
5 :  4
Tampa Bay Rays
W W W W W W
Victories

6/6 (100%)

Defeats

0/6 (0%)

Jul 13, 2025 - MLB

Boston Red Sox
4 :  1
Tampa Bay Rays

Jul 12, 2025 - MLB

Boston Red Sox
1 :  0
Tampa Bay Rays

Jul 11, 2025 - MLB

Boston Red Sox
5 :  4
Tampa Bay Rays

Jul 10, 2025 - MLB

Boston Red Sox
4 :  3
Tampa Bay Rays

Jul 9, 2025 - MLB

Boston Red Sox
10 :  2
Colorado Rockies

Jul 8, 2025 - MLB

Boston Red Sox
10 :  2
Colorado Rockies
W W W L L W
Victories

4/6 (67%)

Defeats

2/6 (33%)

Jul 20, 2025 - MLB

Chicago Cubs
1 :  6
Boston Red Sox

Jul 19, 2025 - MLB

Chicago Cubs
6 :  0
Boston Red Sox

Jul 18, 2025 - MLB

Chicago Cubs
4 :  1
Boston Red Sox

Jul 6, 2025 - MLB

Washington Nationals
4 :  6
Boston Red Sox

Jul 5, 2025 - MLB

Washington Nationals
3 :  10
Boston Red Sox

Jul 4, 2025 - MLB

Washington Nationals
2 :  11
Boston Red Sox

Philadelphia Phillies against Boston Red Sox : Head to Head (H2H)

Philadelphia Phillies

40 %

Boston Red Sox

60 %

Jun 13, 2024 - MLB

Boston Red Sox
9 :  3
Philadelphia Phillies

Jun 12, 2024 - MLB

Boston Red Sox
8 :  6
Philadelphia Phillies

Jun 11, 2024 - MLB

Boston Red Sox
1 :  4
Philadelphia Phillies

Mar 14, 2024 - MLB Spring Training

Philadelphia Phillies
6 :  1
Boston Red Sox

Feb 26, 2024 - MLB Spring Training

Boston Red Sox
7 :  6
Philadelphia Phillies

Philadelphia Phillies - Boston Red Sox Key Points

  1. Boston leads the all-time series vs. Philadelphia 56-36.
  2. Wheeler allowed one earned run in his last home start, a home run; it was the only hit he surrendered in a complete game; he surrendered three total runs across his last five starts.
  3. Buehler only gave up two earned runs in his last road start, but has given up a total of 25 across his last five road starts.
  4. Betting Public: 85% of runline tickets and 91% of the handle are on Philadelphia.

Our Philadelphia Phillies vs Boston Red Sox Prediction

What do you get when you take a struggling pitcher and give him a road start (where he happens to play his worst), and his opponent is one of the best homefield pitchers in baseball? You get a one-sided, ugly game, which in this case means a win for the Phillies. Boston’s lineup doesn’t stand a chance against Wheeler; I expect fireworks from the Philly lineup vs. Buehler.

Our Boston vs. Philadelphia Pick: Phillies -2.5 (alt runline)

Prediction:

 

Phillies -2.5

+144
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Philadelphia Phillies vs Boston Red Sox Picks