Boston Red Sox vs Philadelphia Phillies Prediction & Picks - MLB

USA - MLB

Boston Red Sox
7/21/25 18:45
Philadelphia Phillies

Prediction:

 

Phillies -2.5

+144
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 by Travis Pulver in MLB Picks

The Phillies will host the Boston Red Sox at Citizens Bank Park in Philadelphia in a three-game series. Game One of this series is scheduled for 6:45 p.m. EST.

Both teams got the second half of the season off to a rough start, losing two of three games over the weekend. Boston dropped the first two vs. the Cubs in Chicago, 4-12 and 6-1. But the offense came alive in the series finale, and they won the finale, 6-1. Philadelphia lost its opener vs. the Los Angeles Angels 6-5 but bounced back and won the second 9-5, but lost the series finale Sunday 8-2. The Red Sox have Walker Buehler scheduled to start. Buehler has gone 6-6 in 16 starts with a 6.12 ERA, 1.56 WHIP, and .282 OBA. He has had a hard time on the road this season, going 3-4 in eight starts with an 8.66 ERA and .342 OBA. Philadelphia is scheduled to start Zack Wheeler. Wheeler is 9-3 in 19 starts with a 2.36 ERA, .86 WHIP, and .181 OBA. He has been at his best at home, where he is 6-1 in ten starts with a 1.91 ERA and .164 OBA.

Boston Red Sox vs Philadelphia Phillies Form

Table

Teams % P W L
7
Philadelphia Phillies
Philadelphia Phillies
0.566 99 56 43
11
Boston Red Sox
Boston Red Sox
0.535 101 54 47

Boston Red Sox and Philadelphia Phillies Latest Matches

Boston Red Sox
Boston Red Sox Latest matches
W W W L L W
Victories

4/6 (67%)

Defeats

2/6 (33%)

Jul 20, 2025 - MLB

Boston Red Sox
6 :  1
Chicago Cubs

Jul 19, 2025 - MLB

Boston Red Sox
0 :  6
Chicago Cubs

Jul 18, 2025 - MLB

Boston Red Sox
1 :  4
Chicago Cubs

Jul 13, 2025 - MLB

Tampa Bay Rays
1 :  4
Boston Red Sox

Jul 12, 2025 - MLB

Tampa Bay Rays
0 :  1
Boston Red Sox

Jul 11, 2025 - MLB

Tampa Bay Rays
4 :  5
Boston Red Sox
W W W W W W
Victories

6/6 (100%)

Defeats

0/6 (0%)

Jul 13, 2025 - MLB

Tampa Bay Rays
1 :  4
Boston Red Sox

Jul 12, 2025 - MLB

Tampa Bay Rays
0 :  1
Boston Red Sox

Jul 11, 2025 - MLB

Tampa Bay Rays
4 :  5
Boston Red Sox

Jul 10, 2025 - MLB

Tampa Bay Rays
3 :  4
Boston Red Sox

Jul 9, 2025 - MLB

Colorado Rockies
2 :  10
Boston Red Sox

Jul 8, 2025 - MLB

Colorado Rockies
2 :  10
Boston Red Sox
W W W L L W
Victories

4/6 (67%)

Defeats

2/6 (33%)

Jul 20, 2025 - MLB

Boston Red Sox
6 :  1
Chicago Cubs

Jul 19, 2025 - MLB

Boston Red Sox
0 :  6
Chicago Cubs

Jul 18, 2025 - MLB

Boston Red Sox
1 :  4
Chicago Cubs

Jul 6, 2025 - MLB

Boston Red Sox
6 :  4
Washington Nationals

Jul 5, 2025 - MLB

Boston Red Sox
10 :  3
Washington Nationals

Jul 4, 2025 - MLB

Boston Red Sox
11 :  2
Washington Nationals
Philadelphia Phillies
Philadelphia Phillies Latest matches
L L W L W L
Victories

2/6 (33%)

Defeats

4/6 (67%)

Jul 20, 2025 - MLB

Los Angeles Angels
8 :  2
Philadelphia Phillies

Jul 19, 2025 - MLB

Los Angeles Angels
5 :  9
Philadelphia Phillies

Jul 18, 2025 - MLB

Los Angeles Angels
6 :  5
Philadelphia Phillies

Jul 13, 2025 - MLB

Philadelphia Phillies
2 :  1
San Diego Padres

Jul 12, 2025 - MLB

Philadelphia Phillies
4 :  5
San Diego Padres

Jul 11, 2025 - MLB

Philadelphia Phillies
2 :  4
San Diego Padres
L W W L W L
Victories

3/6 (50%)

Defeats

3/6 (50%)

Jul 20, 2025 - MLB

Los Angeles Angels
8 :  2
Philadelphia Phillies

Jul 19, 2025 - MLB

Los Angeles Angels
5 :  9
Philadelphia Phillies

Jul 18, 2025 - MLB

Los Angeles Angels
6 :  5
Philadelphia Phillies

Jul 6, 2025 - MLB

Cincinnati Reds
1 :  3
Philadelphia Phillies

Jul 5, 2025 - MLB

Cincinnati Reds
1 :  5
Philadelphia Phillies

Jul 4, 2025 - MLB

Cincinnati Reds
9 :  6
Philadelphia Phillies
L L W L L W
Victories

2/6 (33%)

Defeats

4/6 (67%)

Jul 13, 2025 - MLB

Philadelphia Phillies
2 :  1
San Diego Padres

Jul 12, 2025 - MLB

Philadelphia Phillies
4 :  5
San Diego Padres

Jul 11, 2025 - MLB

Philadelphia Phillies
2 :  4
San Diego Padres

Jul 9, 2025 - MLB

Philadelphia Phillies
13 :  0
San Francisco Giants

Jul 8, 2025 - MLB

Philadelphia Phillies
3 :  4
San Francisco Giants

Jul 7, 2025 - MLB

Philadelphia Phillies
1 :  3
San Francisco Giants

Boston Red Sox against Philadelphia Phillies : Head to Head (H2H)

Boston Red Sox

33 %

Philadelphia Phillies

67 %

Mar 11, 2025 - MLB Spring Training

Philadelphia Phillies
18 :  8
Boston Red Sox

Feb 28, 2025 - MLB Spring Training

Boston Red Sox
5 :  7
Philadelphia Phillies

Jun 13, 2024 - MLB

Philadelphia Phillies
3 :  9
Boston Red Sox

Jun 12, 2024 - MLB

Philadelphia Phillies
6 :  8
Boston Red Sox

Jun 11, 2024 - MLB

Philadelphia Phillies
4 :  1
Boston Red Sox

Mar 14, 2024 - MLB Spring Training

Boston Red Sox
1 :  6
Philadelphia Phillies

Boston Red Sox - Philadelphia Phillies Key Points

  1. Boston leads the all-time series vs. Philadelphia 56-36.
  2. Wheeler allowed one earned run in his last home start, a home run; it was the only hit he surrendered in a complete game; he surrendered three total runs across his last five starts.
  3. Buehler only gave up two earned runs in his last road start, but has given up a total of 25 across his last five road starts.
  4. Betting Public: 85% of runline tickets and 91% of the handle are on Philadelphia.

Our Boston Red Sox vs Philadelphia Phillies Prediction

What do you get when you take a struggling pitcher and give him a road start (where he happens to play his worst), and his opponent is one of the best homefield pitchers in baseball? You get a one-sided, ugly game, which in this case means a win for the Phillies. Boston’s lineup doesn’t stand a chance against Wheeler; I expect fireworks from the Philly lineup vs. Buehler.

Our Boston vs. Philadelphia Pick: Phillies -2.5 (alt runline)

Prediction:

 

Phillies -2.5

+144
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Boston Red Sox vs Philadelphia Phillies Picks