Houston Astros vs Boston Red Sox Prediction & Picks - MLB

USA - MLB

Houston Astros
3/31/26 20:10
Boston Red Sox

Prediction:

 

Houston Astros on the -1 run line.

-106
$200 offered for betting!

New customers only | Commercial content | 21+ age limit | T&Cs apply

 by Stephen Abiola | in MLB Picks

Houston Astros and Boston Red Sox will meet under the lights at Daikin Park on Tuesday night. The Astros started this series with a bang, defeating the Red Sox 8-1 on Monday night. McCullers was the star of the show with seven strong innings while Altuve had two homers to power the Astros past the helpless Red Sox. Earlier, the Astros went 2-2 on their thrilling opening series against the Angels.

Boston Red Sox, on the other hand, started the season on the wrong foot, losing their first series against the Reds 2-1. So far, questions are already being asked about their “run prevention” strategy after giving up a total of 17 runs in three matches. The Red Sox will know that they cannot afford to give away a lot of runs against elite teams if they want to excel in the AL East. And yes, they were bang average for the majority of last season.

Up to $200 to bet on Houston Astros - Boston Red Sox! 

Limited Offer. Currently at DraftKings

Houston Astros vs Boston Red Sox Form

Table

Teams Pts P W L
18 Houston Astros
0.482 85 41 44
24 Boston Red Sox
0.432 81 35 46

Houston Astros and Boston Red Sox Latest Matches

Houston Astros
Houston Astros Latest matches
L L L W W W
Victories

3/6 (50%)

Defeats

3/6 (50%)

Mar 30, 2026 - MLB

Houston Astros
8 :  1
Boston Red Sox

Mar 29, 2026 - MLB

Houston Astros
9 :  7
Los Angeles Angels

Mar 28, 2026 - MLB

Houston Astros
11 :  9
Los Angeles Angels

Mar 27, 2026 - MLB

Houston Astros
2 :  6
Los Angeles Angels

Mar 26, 2026 - MLB

Houston Astros
0 :  3
Los Angeles Angels

Mar 22, 2026 - MLB Spring Training

Houston Astros
2 :  3
St. Louis Cardinals
L L L W W W
Victories

3/6 (50%)

Defeats

3/6 (50%)

Mar 30, 2026 - MLB

Houston Astros
8 :  1
Boston Red Sox

Mar 29, 2026 - MLB

Houston Astros
9 :  7
Los Angeles Angels

Mar 28, 2026 - MLB

Houston Astros
11 :  9
Los Angeles Angels

Mar 27, 2026 - MLB

Houston Astros
2 :  6
Los Angeles Angels

Mar 26, 2026 - MLB

Houston Astros
0 :  3
Los Angeles Angels

Mar 22, 2026 - MLB Spring Training

Houston Astros
2 :  3
St. Louis Cardinals
L W L W L W
Victories

3/6 (50%)

Defeats

3/6 (50%)

Mar 21, 2026 - MLB Spring Training

New York Mets
5 :  7
Houston Astros

Mar 18, 2026 - MLB Spring Training

St. Louis Cardinals
4 :  1
Houston Astros

Mar 17, 2026 - MLB Spring Training

Pittsburgh Pirates
2 :  10
Houston Astros

Mar 13, 2026 - MLB Spring Training

St. Louis Cardinals
5 :  4
Houston Astros

Mar 11, 2026 - MLB Spring Training

Miami Marlins
1 :  4
Houston Astros

Mar 8, 2026 - MLB Spring Training

Washington Nationals
3 :  1
Houston Astros
Boston Red Sox
Boston Red Sox Latest matches
L L W L L L
Victories

1/6 (17%)

Defeats

5/6 (83%)

Mar 30, 2026 - MLB

Houston Astros
8 :  1
Boston Red Sox

Mar 29, 2026 - MLB

Cincinnati Reds
3 :  2
Boston Red Sox

Mar 28, 2026 - MLB

Cincinnati Reds
6 :  5
Boston Red Sox

Mar 26, 2026 - MLB

Cincinnati Reds
0 :  3
Boston Red Sox

Mar 24, 2026 - MLB Spring Training

Minnesota Twins
15 :  6
Boston Red Sox

Mar 23, 2026 - MLB Spring Training

Boston Red Sox
6 :  9
Minnesota Twins
W W W W L L
Victories

4/6 (67%)

Defeats

2/6 (33%)

Mar 23, 2026 - MLB Spring Training

Boston Red Sox
6 :  9
Minnesota Twins

Mar 21, 2026 - MLB Spring Training

Boston Red Sox
1 :  6
Atlanta Braves

Mar 19, 2026 - MLB Spring Training

Boston Red Sox
4 :  2
Minnesota Twins

Mar 17, 2026 - MLB Spring Training

Boston Red Sox
4 :  3
Atlanta Braves

Mar 15, 2026 - MLB Spring Training

Boston Red Sox
7 :  2
Minnesota Twins

Mar 13, 2026 - MLB Spring Training

Boston Red Sox
7 :  6
Tampa Bay Rays
W L W L L L
Victories

2/6 (33%)

Defeats

4/6 (67%)

Mar 30, 2026 - MLB

Houston Astros
8 :  1
Boston Red Sox

Mar 29, 2026 - MLB

Cincinnati Reds
3 :  2
Boston Red Sox

Mar 28, 2026 - MLB

Cincinnati Reds
6 :  5
Boston Red Sox

Mar 26, 2026 - MLB

Cincinnati Reds
0 :  3
Boston Red Sox

Mar 24, 2026 - MLB Spring Training

Minnesota Twins
15 :  6
Boston Red Sox

Mar 22, 2026 - MLB Spring Training

Pittsburgh Pirates
3 :  6
Boston Red Sox

Houston Astros against Boston Red Sox : Head to Head (H2H)

Houston Astros

50 %

Boston Red Sox

50 %

Mar 30, 2026 - MLB

Houston Astros
8 :  1
Boston Red Sox

Aug 13, 2025 - MLB

Houston Astros
4 :  1
Boston Red Sox

Aug 12, 2025 - MLB

Houston Astros
1 :  14
Boston Red Sox

Aug 11, 2025 - MLB

Houston Astros
7 :  6
Boston Red Sox

Aug 3, 2025 - MLB

Boston Red Sox
6 :  1
Houston Astros

Aug 2, 2025 - MLB

Boston Red Sox
7 :  3
Houston Astros

Houston Astros - Boston Red Sox Key Points

  1. Houston Astros are 3-1 on the run line in their last four games.
  2. Boston Red Sox are 1-5 on the run line in their last six matches.
  3. Houston Red Sox are 2-11 in their last 13 away matches.
  4. Houston Astros are 3-1 in their last four home games.
Up to $200 to bet on Houston Astros - Boston Red Sox! 

Limited Offer. Currently at DraftKings

Our Houston Astros vs Boston Red Sox Prediction

Houston Astros carry all the advantages into this game, with bookmakers listing them as the -177 betting favorites. The head-to-head record backs them to win, having won three of their last four matches against the Red Sox. They also boast a similar record in their four previous clashes at Daikin Park. The Astros will face Roger Suarez, whom they have a solid track record against. They’ve hit .283 off him across 60 at-bats. Yordan Alvarez, who has already hit .308 this season, will certainly fancy his chances of hitting a double against the lefty. Still, we expect Suarez to get through at least five innings tonight.

Our prediction for Houston Astros vs Boston Red Sox: Houston Astros on the -1 run line.

Prediction:

 

Houston Astros on the -1 run line.

-106
$200 offered for betting!

All tips are fully researched and given in good faith, but profits cannot be guaranteed.

Houston Astros vs Boston Red Sox Picks