Detroit Tigers vs Boston Red Sox Prediction & Picks - MLB

USA - MLB

Detroit Tigers
5/5/26 18:40
Boston Red Sox

Prediction:

 

The Tigers -1.5 Runs

+110
$250 offered for betting!

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 by Lou Aguila | in MLB Picks

The Detroit Tigers will try to level the series with the Boston Red Sox in Game 2 on Tuesday. The Tigers offer a +110 price if they overcome a 1.5-run handicap in this game.

Current Form:

The Boston Red Sox claimed their second win in six games after edging the Detroit Tigers, 5-4, in Game 1 of their series. The win, however, hasn’t helped the Red Sox’s odds of winning Game 2. Caesars still view them as heavy underdogs at +158 moneyline and -130 on the +1.5-game on the spread line.

Boston bumps up their average run per game over the last five games to 2.6 runs after scoring at least five runs in a match for the first time since beating the Toronto Blue Jays 5-0 on April 27. The Red Sox have also lowered their ERA to 3.80 over the last five games.

Aside from the loss in the series opener, Detroit got a double black eye on Monday after learning that two-time CY Young Award winner Tarik Skubal will miss several months because of an elbow injury. With their ace pitcher sidelined for the foreseeable future, the Tigers will now have to rely more on their other starters and their vaunted bullpen, which has commanded an outstanding 2.33 ERA over the last five games.

The Tigers remain a strong offensive unit, averaging 5.2 runs per game on a .247 BA over the last five games. In their last three meeting against Boston, Detroit has averaged 5.33 runs and 8.33 hits per game.

Starting Pitchers: Red Sox LHP Jovani Moran (0-0, 2.33 ERA)_vs. Tigers LHP Framber Valdez (2-1, 3.35 ERA).

Moran is scheduled for his first start after coming off the bullpen in his last 10 mound appearances this season. Valdez has been steady since giving up 8 runs over 5 innings against Minnesota on April 8. The veteran has guided the Tigers to three wins in his last four starts, during which he has surrendered 6 earned runs over 23.1 innings.

Up to $250 to bet on Detroit Tigers - Boston Red Sox! 

Limited Offer. Currently at Caesars Sportsbook

Detroit Tigers vs Boston Red Sox Form

Table

Teams Pts P W L
24 Boston Red Sox
0.432 81 35 46
25 Detroit Tigers
0.422 83 35 48

Detroit Tigers and Boston Red Sox Latest Matches

Detroit Tigers
Detroit Tigers Latest matches
L W L W W L
Victories

3/6 (50%)

Defeats

3/6 (50%)

May 4, 2026 - MLB

Detroit Tigers
4 :  5
Boston Red Sox

May 3, 2026 - MLB

Detroit Tigers
7 :  1
Texas Rangers

May 2, 2026 - MLB

Detroit Tigers
5 :  1
Texas Rangers

May 1, 2026 - MLB

Detroit Tigers
4 :  5
Texas Rangers

Apr 30, 2026 - MLB

Atlanta Braves
2 :  5
Detroit Tigers

Apr 29, 2026 - MLB

Atlanta Braves
4 :  3
Detroit Tigers
W W L W W L
Victories

4/6 (67%)

Defeats

2/6 (33%)

May 4, 2026 - MLB

Detroit Tigers
4 :  5
Boston Red Sox

May 3, 2026 - MLB

Detroit Tigers
7 :  1
Texas Rangers

May 2, 2026 - MLB

Detroit Tigers
5 :  1
Texas Rangers

May 1, 2026 - MLB

Detroit Tigers
4 :  5
Texas Rangers

Apr 23, 2026 - MLB

Detroit Tigers
5 :  4
Milwaukee Brewers

Apr 22, 2026 - MLB

Detroit Tigers
5 :  2
Milwaukee Brewers
L L W L L W
Victories

2/6 (33%)

Defeats

4/6 (67%)

Apr 30, 2026 - MLB

Atlanta Braves
2 :  5
Detroit Tigers

Apr 29, 2026 - MLB

Atlanta Braves
4 :  3
Detroit Tigers

Apr 28, 2026 - MLB

Atlanta Braves
5 :  2
Detroit Tigers

Apr 26, 2026 - MLB

Cincinnati Reds
3 :  8
Detroit Tigers

Apr 25, 2026 - MLB

Cincinnati Reds
9 :  2
Detroit Tigers

Apr 24, 2026 - MLB

Cincinnati Reds
9 :  8
Detroit Tigers
Boston Red Sox
Boston Red Sox Latest matches
L L W L L W
Victories

2/6 (33%)

Defeats

4/6 (67%)

May 4, 2026 - MLB

Detroit Tigers
4 :  5
Boston Red Sox

May 3, 2026 - MLB

Boston Red Sox
1 :  3
Houston Astros

May 2, 2026 - MLB

Boston Red Sox
3 :  6
Houston Astros

May 1, 2026 - MLB

Boston Red Sox
3 :  1
Houston Astros

Apr 29, 2026 - MLB

Toronto Blue Jays
8 :  1
Boston Red Sox

Apr 28, 2026 - MLB

Toronto Blue Jays
3 :  0
Boston Red Sox
L L L W L L
Victories

1/6 (17%)

Defeats

5/6 (83%)

May 3, 2026 - MLB

Boston Red Sox
1 :  3
Houston Astros

May 2, 2026 - MLB

Boston Red Sox
3 :  6
Houston Astros

May 1, 2026 - MLB

Boston Red Sox
3 :  1
Houston Astros

Apr 23, 2026 - MLB

Boston Red Sox
2 :  4
New York Yankees

Apr 22, 2026 - MLB

Boston Red Sox
1 :  4
New York Yankees

Apr 21, 2026 - MLB

Boston Red Sox
0 :  4
New York Yankees
W W W L L W
Victories

4/6 (67%)

Defeats

2/6 (33%)

May 4, 2026 - MLB

Detroit Tigers
4 :  5
Boston Red Sox

Apr 29, 2026 - MLB

Toronto Blue Jays
8 :  1
Boston Red Sox

Apr 28, 2026 - MLB

Toronto Blue Jays
3 :  0
Boston Red Sox

Apr 27, 2026 - MLB

Toronto Blue Jays
0 :  5
Boston Red Sox

Apr 26, 2026 - MLB

Baltimore Orioles
3 :  5
Boston Red Sox

Apr 25, 2026 - MLB

Baltimore Orioles
1 :  17
Boston Red Sox

Detroit Tigers against Boston Red Sox : Head to Head (H2H)

Detroit Tigers

50 %

Boston Red Sox

50 %

May 4, 2026 - MLB

Detroit Tigers
4 :  5
Boston Red Sox

Apr 20, 2026 - MLB

Boston Red Sox
8 :  6
Detroit Tigers

Apr 19, 2026 - MLB

Boston Red Sox
2 :  6
Detroit Tigers

Apr 18, 2026 - MLB

Boston Red Sox
1 :  4
Detroit Tigers

Apr 17, 2026 - MLB

Boston Red Sox
1 :  0
Detroit Tigers

Mar 10, 2026 - MLB Spring Training

Boston Red Sox
2 :  7
Detroit Tigers

Detroit Tigers - Boston Red Sox Key Points

  1. Boston is 2-4 SU in its last 6 games.
  2. Boston is 1-5 SU in its last 6 games when playing on the road against Detroit.
  3. Detroit is 10-3 SU in its last 13 games at home.
  4. Detroit is 5-1 SU in its last 6 games when playing at home against Boston.
Up to $250 to bet on Detroit Tigers - Boston Red Sox! 

Limited Offer. Currently at Caesars Sportsbook

Our Detroit Tigers vs Boston Red Sox Prediction

Hot Take: The Tigers will level the series at 1-1 with a strong win over the Red Sox in Game 2.

Valdez is poised to replicate his strong performance against Boston on April 19, in which he stifled the Red Sox’s offense by allowing one earned run over six innings. Detroit’s bullpen will also be a factor in this game after posting a rock-solid 2.33 ERA over the last five games. Detroit holds a 12-4 slate against the spread in their 16 games at Comerica Park, reinforcing the chances of overcoming a -1.5-run handicap valued at +110.

As for Boston, the Red Sox are 8-11 on the road this season. Their pitchers are much more hittable on the road, with a 4.66 ERA. Again, trusting their offense to outscore Detroit for the second straight game would require a lot of belief, as Boston has averaged only 2.6 runs per game over the last five games.

Our betting prediction for the Boston Red Sox vs. the Detroit Tigers: The Tigers -1.5 runs.

Prediction:

 

The Tigers -1.5 Runs

+110
$250 offered for betting!

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All tips are fully researched and given in good faith, but profits cannot be guaranteed.

Detroit Tigers vs Boston Red Sox Picks