Cleveland Guardians vs Boston Red Sox Prediction & Picks - MLB

USA - MLB

Cleveland Guardians
4/27/25 13:40
Boston Red Sox

Prediction:

 

UNDER 7.5

 

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 by Travis Pulver | in MLB Picks

The Boston Red Sox will close out a weekend road trip to Cleveland today with the final game of their weekend series vs. the Indians at Progressive Field in Cleveland, OH. Fans can follow the action once the game gets underway at 1:40 p.m. EST.

With Friday’s game getting postponed, the Red Sox and Indians played a doubleheader Saturday. Cleveland won the first game 5-4. Boston got on top early with three runs in the top of the first, but the lead did not last with the Indians scoring four in the bottom of the inning. The Red Sox tied the game up with a run in the third, but then the Indians scored the go-ahead run in the sixth. In the second game, the Boston lineup built an early lead with six runs off Cleveland starter Doug Nikhazy within the first three innings. They went on to win 7-3.

Boston will give the ball to Brayan Bello to start the day. Bello got the win in his only other start,  vs. Seattle, on Tuesday (five innings, four hits, one earned run, three walks, and three strikeouts). Cleveland will go with Logan Allen on the mound. The young lefty is 1-1 on the season in four starts with a 2.11 ERA.

Cleveland Guardians vs Boston Red Sox Form

Table

Teams Pts P W L
9 Boston Red Sox
0.549 162 89 73
10 Cleveland Guardians
0.543 162 88 74

Cleveland Guardians and Boston Red Sox Latest Matches

Cleveland Guardians
Cleveland Guardians Latest matches
W W W W L L
Victories

4/6 (67%)

Defeats

2/6 (33%)

Apr 26, 2025 - MLB

Cleveland Guardians
3 :  7
Boston Red Sox

Apr 23, 2025 - MLB

Cleveland Guardians
1 :  5
New York Yankees

Apr 22, 2025 - MLB

Cleveland Guardians
3 :  2
New York Yankees

Apr 21, 2025 - MLB

Cleveland Guardians
6 :  4
New York Yankees

Apr 20, 2025 - MLB

Pittsburgh Pirates
4 :  5
Cleveland Guardians

Apr 19, 2025 - MLB

Pittsburgh Pirates
0 :  3
Cleveland Guardians
W L W W L L
Victories

3/6 (50%)

Defeats

3/6 (50%)

Apr 26, 2025 - MLB

Cleveland Guardians
3 :  7
Boston Red Sox

Apr 23, 2025 - MLB

Cleveland Guardians
1 :  5
New York Yankees

Apr 22, 2025 - MLB

Cleveland Guardians
3 :  2
New York Yankees

Apr 21, 2025 - MLB

Cleveland Guardians
6 :  4
New York Yankees

Apr 13, 2025 - MLB

Cleveland Guardians
2 :  4
Kansas City Royals

Apr 12, 2025 - MLB

Cleveland Guardians
6 :  3
Kansas City Royals
W L L W W W
Victories

4/6 (67%)

Defeats

2/6 (33%)

Apr 20, 2025 - MLB

Pittsburgh Pirates
4 :  5
Cleveland Guardians

Apr 19, 2025 - MLB

Pittsburgh Pirates
0 :  3
Cleveland Guardians

Apr 18, 2025 - MLB

Pittsburgh Pirates
7 :  10
Cleveland Guardians

Apr 17, 2025 - MLB

Baltimore Orioles
6 :  2
Cleveland Guardians

Apr 16, 2025 - MLB

Baltimore Orioles
9 :  1
Cleveland Guardians

Apr 15, 2025 - MLB

Baltimore Orioles
3 :  6
Cleveland Guardians
Boston Red Sox
Boston Red Sox Latest matches
L W W L L W
Victories

3/6 (50%)

Defeats

3/6 (50%)

Apr 26, 2025 - MLB

Cleveland Guardians
3 :  7
Boston Red Sox

Apr 24, 2025 - MLB

Boston Red Sox
3 :  4
Seattle Mariners

Apr 23, 2025 - MLB

Boston Red Sox
5 :  8
Seattle Mariners

Apr 22, 2025 - MLB

Boston Red Sox
8 :  3
Seattle Mariners

Apr 21, 2025 - MLB

Boston Red Sox
4 :  2
Chicago White Sox

Apr 20, 2025 - MLB

Boston Red Sox
4 :  8
Chicago White Sox
W L W W L L
Victories

3/6 (50%)

Defeats

3/6 (50%)

Apr 24, 2025 - MLB

Boston Red Sox
3 :  4
Seattle Mariners

Apr 23, 2025 - MLB

Boston Red Sox
5 :  8
Seattle Mariners

Apr 22, 2025 - MLB

Boston Red Sox
8 :  3
Seattle Mariners

Apr 21, 2025 - MLB

Boston Red Sox
4 :  2
Chicago White Sox

Apr 20, 2025 - MLB

Boston Red Sox
4 :  8
Chicago White Sox

Apr 19, 2025 - MLB

Boston Red Sox
4 :  3
Chicago White Sox
L W L W W W
Victories

4/6 (67%)

Defeats

2/6 (33%)

Apr 26, 2025 - MLB

Cleveland Guardians
3 :  7
Boston Red Sox

Apr 16, 2025 - MLB

Tampa Bay Rays
0 :  1
Boston Red Sox

Apr 15, 2025 - MLB

Tampa Bay Rays
4 :  7
Boston Red Sox

Apr 14, 2025 - MLB

Tampa Bay Rays
16 :  1
Boston Red Sox

Apr 13, 2025 - MLB

Chicago White Sox
1 :  3
Boston Red Sox

Apr 12, 2025 - MLB

Chicago White Sox
3 :  2
Boston Red Sox

Cleveland Guardians against Boston Red Sox : Head to Head (H2H)

Cleveland Guardians

50 %

Boston Red Sox

50 %

Apr 26, 2025 - MLB

Cleveland Guardians
3 :  7
Boston Red Sox

Apr 25, 2024 - MLB

Cleveland Guardians
6 :  4
Boston Red Sox

Apr 24, 2024 - MLB

Cleveland Guardians
0 :  8
Boston Red Sox

Apr 23, 2024 - MLB

Cleveland Guardians
4 :  1
Boston Red Sox

Apr 18, 2024 - MLB

Boston Red Sox
4 :  5
Cleveland Guardians

Apr 17, 2024 - MLB

Boston Red Sox
2 :  0
Cleveland Guardians

Cleveland Guardians - Boston Red Sox Key Points

  1. Cleveland leads the all-time series vs. Boston 1073-1010-8.
  2. Cleveland won the season series last year, 5-2.
  3. The Red Sox are 7-8 away from home while the Indians are 8-3 at home.
  4. Betting Splits: 50% of moneyline tickets are on each team, but 82% of the handle is on Boston.

Our Cleveland Guardians vs Boston Red Sox Prediction

I’m guessing the public is all over the OVER (7.5 runs) since both games yesterday went over. But both starting pitchers are looking good; Bello gave up one run in his only start, and Allen has given up one across his last three starts. My only concern about taking the UNDER is that Boston’s pen has a 4.12 ERA relative to a 3.12 ERA for Cleveland. But the Indians are only hitting .236 over the last week (Boston-- .239 BA).

Our Red Sox vs. Indians Pick: UNDER 7.5

Prediction:

 

UNDER 7.5

 

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Cleveland Guardians vs Boston Red Sox Picks