Benfica Lisbon vs Bayer Leverkusen Prediction & Picks - Champions League

Europe - Champions League

Benfica Lisbon
11/5/25 15:00
Bayer Leverkusen

Prediction:

 

Benfica Lisbon wins

+100
$150 offered for betting!

New customers only | Commercial content | 21+ age limit | T&Cs apply

 by Carlos Zabala in Champions League Picks

Benfica will face Bayer Leverkusen, the Aspirins of the Bundesliga, in a match between two clubs accustomed to competing in Europe but who have had a discouraging start to this season's Champions League. For the first time in nine years, Bayer Leverkusen has failed to win any of its three European matches, while Mourinho's Benfica sits second-to-last in the 36-team group, having not won a single game and boasting a goal difference of -5.

The loser of this match will undoubtedly see their chances of advancing to the next round drastically reduced. As for the betting odds, bookmakers have set Benfica at around 2.05 as the favorite to win on Wednesday at the Estádio da Luz.

Between 2013 and 2014, there were four encounters between Bayer Leverkusen and Benfica, with the Eagles winning the first two in the Europa League and Bayer Leverkusen winning the third 3-1 in the Champions League. The fourth match ended in a goalless draw in Portugal.

Benfica Lisbon vs Bayer Leverkusen Form

Table

Teams Pts P W D L GD
29
Bayer Leverkusen
Bayer Leverkusen
2 3 0 2 1 -5
35
Benfica Lisbon
Benfica Lisbon
0 3 0 0 3 -5

Benfica Lisbon and Bayer Leverkusen Latest Matches

Benfica Lisbon
Benfica Lisbon Latest matches
D W L W W W
Victories

4/6 (67%)

Draw

1/6 (17%)

Defeats

1/6 (17%)

Average stats (Last 6 matchs)

2.67 Total goals
0% BTTS
2.17 Goals scored
0.5 Goals conceded
67% Over 2.5
33% Under 2.5

Nov 1, 2025 - Liga Portugal

Vitoria SC Guimaraes
0 :  3
Benfica Lisbon

Oct 29, 2025 - Portugal League Cup

Benfica Lisbon
3 :  0
Tondela

Oct 25, 2025 - Liga Portugal

Benfica Lisbon
5 :  0
Arouca

Oct 21, 2025 - Champions League

Newcastle
3 :  0
Benfica Lisbon

Oct 17, 2025 - Taca de Portugal

Chaves
0 :  2
Benfica Lisbon

Oct 5, 2025 - Liga Portugal

Porto
0 :  0
Benfica Lisbon
D L D W W W
Victories

3/6 (50%)

Draw

2/6 (33%)

Defeats

1/6 (17%)

Average stats (Last 6 matchs)

3.33 Total goals
67% BTTS
2.33 Goals scored
1 Goals conceded
67% Over 2.5
33% Under 2.5

Oct 29, 2025 - Portugal League Cup

Benfica Lisbon
3 :  0
Tondela

Oct 25, 2025 - Liga Portugal

Benfica Lisbon
5 :  0
Arouca

Sep 26, 2025 - Liga Portugal

Benfica Lisbon
2 :  1
Gil Vicente

Sep 23, 2025 - Liga Portugal

Benfica Lisbon
1 :  1
Rio Ave

Sep 16, 2025 - Champions League

Benfica Lisbon
2 :  3
Qarabag FK

Sep 12, 2025 - Liga Portugal

Benfica Lisbon
1 :  1
Santa Clara
W L D W L W
Victories

3/6 (50%)

Draw

1/6 (17%)

Defeats

2/6 (33%)

Average stats (Last 6 matchs)

2 Total goals
0% BTTS
1.33 Goals scored
0.67 Goals conceded
50% Over 2.5
50% Under 2.5

Nov 1, 2025 - Liga Portugal

Vitoria SC Guimaraes
0 :  3
Benfica Lisbon

Oct 21, 2025 - Champions League

Newcastle
3 :  0
Benfica Lisbon

Oct 17, 2025 - Taca de Portugal

Chaves
0 :  2
Benfica Lisbon

Oct 5, 2025 - Liga Portugal

Porto
0 :  0
Benfica Lisbon

Sep 30, 2025 - Champions League

Chelsea
1 :  0
Benfica Lisbon

Sep 20, 2025 - Liga Portugal

AVS Futebol SAD
0 :  3
Benfica Lisbon
Bayer Leverkusen
Bayer Leverkusen Latest matches
W W L W W L
Victories

4/6 (67%)

Draw

0/6 (0%)

Defeats

2/6 (33%)

Average stats (Last 6 matchs)

4.83 Total goals
50% BTTS
2.33 Goals scored
2.5 Goals conceded
67% Over 2.5
33% Under 2.5

Nov 1, 2025 - Bundesliga

Bayern Munich
3 :  0
Bayer Leverkusen

Oct 29, 2025 - DFB Pokal

Paderborn
2 :  4
Bayer Leverkusen

Oct 26, 2025 - Bundesliga

Bayer Leverkusen
2 :  0
Freiburg

Oct 21, 2025 - Champions League

Bayer Leverkusen
2 :  7
PSG

Oct 18, 2025 - Bundesliga

1 Fsv Mainz 05
3 :  4
Bayer Leverkusen

Oct 4, 2025 - Bundesliga

Bayer Leverkusen
2 :  0
Union Berlin
W D D W L W
Victories

3/6 (50%)

Draw

2/6 (33%)

Defeats

1/6 (17%)

Average stats (Last 6 matchs)

3.5 Total goals
67% BTTS
1.83 Goals scored
1.67 Goals conceded
33% Over 2.5
67% Under 2.5

Oct 26, 2025 - Bundesliga

Bayer Leverkusen
2 :  0
Freiburg

Oct 21, 2025 - Champions League

Bayer Leverkusen
2 :  7
PSG

Oct 4, 2025 - Bundesliga

Bayer Leverkusen
2 :  0
Union Berlin

Oct 1, 2025 - Champions League

Bayer Leverkusen
1 :  1
PSV Eindhoven

Sep 21, 2025 - Bundesliga

Bayer Leverkusen
1 :  1
Mönchengladbach

Sep 12, 2025 - Bundesliga

Bayer Leverkusen
3 :  1
Eintracht Frankfurt
D D W W W L
Victories

3/6 (50%)

Draw

2/6 (33%)

Defeats

1/6 (17%)

Average stats (Last 6 matchs)

4.83 Total goals
83% BTTS
2.5 Goals scored
2.33 Goals conceded
100% Over 2.5
0% Under 2.5

Nov 1, 2025 - Bundesliga

Bayern Munich
3 :  0
Bayer Leverkusen

Oct 29, 2025 - DFB Pokal

Paderborn
2 :  4
Bayer Leverkusen

Oct 18, 2025 - Bundesliga

1 Fsv Mainz 05
3 :  4
Bayer Leverkusen

Sep 27, 2025 - Bundesliga

St. Pauli
1 :  2
Bayer Leverkusen

Sep 18, 2025 - Champions League

FC Copenhagen
2 :  2
Bayer Leverkusen

Aug 30, 2025 - Bundesliga

Werder Bremen
3 :  3
Bayer Leverkusen
Improve your sports betting with our football team comparison tool (100+ statistics)

Bayer Leverkusen v Benfica Lisbon last Lineups

Benfica Lisbon

Formation : 4 - 2 - 3 - 1

1
A. Trubin
8
F. Aursnes
30
N. Otamendi
44
T. Araujo
26
S. Dahl
5
E. Barrenechea
20
R. Rios
11
D. Lukebakio
10
G. Sudakov
25
G. Prestianni
14
V. Pavlidis
14
P. Schick
19
E. Poku
9
C. Echeverri
44
J. Belocian
24
A. Garcia
8
R. Andrich
13
Arthur
12
E. Tapsoba
5
L. Bade
4
J. Quansah
1
M. Flekken

Formation : 3 - 4 - 2 - 1

Bayer Leverkusen

Most goals and assists

CD Huachipato Benfica Lisbon
CD Huachipato Bayer Leverkusen
Top Goalscorer
Greece V. Pavlidis (10 Goals)
Top Goalscorer
Spain A. Grimaldo (7 Goals)
Best assists
Belgium D. Lukebakio (3 Assists)
Best assists
Spain A. Grimaldo (3 Assists)
Netherlands E. Poku (3 Assists)

Benfica Lisbon and Bayer Leverkusen Stats in Champions League

Benfica Lisbon
Benfica Lisbon
Bayer Leverkusen
Bayer Leverkusen
43%
Victories
0%
14%
Draw
67%
43%
Defeats
33%
2
Total goals per match
5
1
Goals scored per match
1.67
1
Goals conceded per match
3.33
29%
Over 2.5
67%
71%
Under 2.5
33%
14%
BTTS
100%
57%
No goals conceded
0%

Benfica Lisbon - Bayer Leverkusen Key Points

  1. Benfica scored 16 goals in the previous Champions League group stage
  2. Benfica had 66% possession in their last Portuguese league match
  3. Bayer Leverkusen only generated an xG of 0.23 in their recent defeat against Bayern Munich
  4. Bayern Munich completed 90% of their attempted passes against Bayer Leverkusen

Our Benfica Lisbon vs Bayer Leverkusen Prediction

This is undoubtedly a Champions League survival match. Both teams find themselves in a similar situation, with new managers taking over mid-season and attempting to address the issues. Kasper Hjulmand, for his part, lost his first match in charge, but Mourinho seems to have recently instilled his team's style, characterized by a tight back line.

Given these factors and the fact that Bayer Leverkusen only managed a last-minute draw in their last away Champions League match against Copenhagen, it appears the Eagles have a strong chance to secure all three points.

Our prediction for Benfica vs Bayer Leverkusen is: Benfica to win.

Prediction:

 

Benfica Lisbon wins

+100
$150 offered for betting!

Grab an extra $150 for your Benfica Lisbon vs Bayer Leverkusen wager!

Bet $5, Get $150

Get ready to experience the thrill of the game with FanDuel's exciting welcome offer, available for use on the Benfica Lisbon vs Bayer Leverkusen matchup!

A minimum bet of $5 will qualify for $150 in bonus bets if your bet wins! This offer is a golden opportunity for new users. Don't miss out on this limited-time deal to enhance your sports betting experience with some extra oomph! Jump into the action today and let FanDuel take your sports engagement to the next level!

$150 available for Benfica Lisbon vs Bayer Leverkusen

All tips are fully researched and given in good faith, but profits cannot be guaranteed.

Benfica Lisbon vs Bayer Leverkusen Picks