Toronto Blue Jays vs Baltimore Orioles Prediction & Picks - MLB

Prediction published on 3/30/25, 10:02 AM  by Carlos Zabala | Modified on 2/16/26 at 4:30 PM in MLB Picks

As has often happened in recent years, the Orioles opened the 2025 season with hot bats. After an opening day where they beat the Blue Jays, the Blue Jays rallied in Game 2, but the Orioles' home runs again opened Game 3 in their favor when Cowser and Westburg, who hit 2 on the day, gave Scherzer home runs in the first inning.

Kremer didn't have a solid performance either, but at least the Orioles' third starter managed to pitch until the 5th inning. In a high note for the Blue Jays, Bo Bichette went 4-for-4, and his team will be delighted that the SS is better than he was in 2024.

Betting sites show slight favoritism for the Blue Jays over the Orioles for Game 4. While the Blue Jays will start with Chris Bassit, who had a 4.16 ERA last season, the Orioles will pitch with Sugano, the Japanese player who will make his MLB debut with high expectations.