New York Yankees vs Baltimore Orioles Prediction & Picks - MLB

Prediction published on 9/26/25, 3:39 PM  by Lou Aguila | Modified on 9/29/25 at 5:08 AM in MLB Picks

The New York Yankees will enter their final series against the Baltimore Orioles, hoping to secure enough wins to steal the AL East title from the Toronto Blue Jays over the weekend.

The Yankees, 5-1 in their last six games against the Orioles, are -152 home favorites but listed at +136 on a -1.5 run line.

Current Form:

Behind a three-game sweep of the White Sox this week, the Yankees have extended their winning streak to five games and improved their record in September to 15-7. They are now tied with the Toronto Blue Jays with a 91-68 record, though the latter still holds the No.1 spot in the AL East because of a tiebreaker. The Yankees have demonstrated exceptional pitching in their last five games with a 1.57 ERA. They have also averaged a solid 6.1 runs per game in this five-game stretch.

The Orioles won two out of three games against the Tampa Bay Rays, raising their record to 75-84, last in the AL East. Baltimore has logged a 4.11 ERA while averaging 3.3 runs per game in their last five games. The Orioles are 4-6 in their previous 10 meetings with the Yankees.