Detroit Tigers vs Baltimore Orioles Prediction & Picks - MLB

Prediction published on 4/27/25, 10:39 AM  by Carlos Zabala | Modified on 4/29/25 at 4:29 AM in MLB Picks

Things are already starting to look bad for the Orioles. They're still waiting for some key bats to emerge, while this season's starting pitching is mediocre and almost always leaves them losing from the start.

Westburg shouldered the bulk of the Orioles' offensive contribution in the first game at Comerica Park, going 3-for-5, while O'Hearn went 3-for-3. Even so, Mize, the Tigers' starter, managed to allow eight hits in 5.1 innings, allowing only one run against the Orioles.

Mize showed encouraging signs of being another competent starter for the Tigers. The Tigers' 12-3 record in Detroit is the third-best home game in MLB. The good news continues, as it will be Skubal, the last Cy Young Award winner, who will start for the Tigers on Sunday. The O's will respond with Kremer, and it feels like Game 1 was their must-win, as the bookmakers aren't optimistic they can beat Skubal, and the Tigers will be favored at -200 odds. The Tigers have now won four straight games against the Orioles.