Cleveland Guardians vs Baltimore Orioles Prediction & Picks - MLB

USA - MLB

Cleveland Guardians
4/18/26 18:10
Baltimore Orioles

Prediction:

 

Baltimore ML

+113
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 by Travis Pulver | in MLB Picks

The Cleveland Guardians (11-10, 5-3 Home) will try to get back on the right side of the scoreboard today when they host the Baltimore Orioles (10-10, 4-4 Away) in Game Three of a three-game series. Fans can follow the game once it gets underway at Progressive Field in Cleveland, OH, at 6:10 p.m. EST on MLB.TV.

Cleveland took Game One of the series on Thursday, 4-2, but then fell to the Orioles in Game Two on Friday, 6-4. The Guardians took the lead when they scored four in the bottom of the seventh, but they didn’t hold it for long. Baltimore responded with six in the top of the 8th to take the lead and secure the win.

Gavin Williams will take the mound to start the day for the Guardians. Williams is 2-1 in four starts with a 2.38 ERA and a 1.15 WHIP. He has given up just three earned runs across his last three starts, including a seven-inning, two-hit shutout of the Dodgers (April 1).

For the Orioles, Dean Kremer will start the day for Baltimore. Kremer has one start to his name this season, a five-inning effort that saw him give up six hits (three home runs) and four runs (two earned) before taking a seat.

Cleveland Guardians vs Baltimore Orioles Form

Table

Teams Pts P W L
12 Cleveland Guardians
0.518 83 43 40
22 Baltimore Orioles
0.464 84 39 45

Cleveland Guardians and Baltimore Orioles Latest Matches

Cleveland Guardians
Cleveland Guardians Latest matches
L W L L W L
Victories

2/6 (33%)

Defeats

4/6 (67%)

Apr 17, 2026 - MLB

Cleveland Guardians
4 :  6
Baltimore Orioles

Apr 16, 2026 - MLB

Cleveland Guardians
4 :  2
Baltimore Orioles

Apr 15, 2026 - MLB

St. Louis Cardinals
5 :  3
Cleveland Guardians

Apr 14, 2026 - MLB

St. Louis Cardinals
6 :  5
Cleveland Guardians

Apr 13, 2026 - MLB

St. Louis Cardinals
3 :  9
Cleveland Guardians

Apr 12, 2026 - MLB

Atlanta Braves
13 :  1
Cleveland Guardians
W L W W W L
Victories

4/6 (67%)

Defeats

2/6 (33%)

Apr 17, 2026 - MLB

Cleveland Guardians
4 :  6
Baltimore Orioles

Apr 16, 2026 - MLB

Cleveland Guardians
4 :  2
Baltimore Orioles

Apr 8, 2026 - MLB

Cleveland Guardians
10 :  2
Kansas City Royals

Apr 7, 2026 - MLB

Cleveland Guardians
2 :  1
Kansas City Royals

Apr 6, 2026 - MLB

Cleveland Guardians
2 :  4
Kansas City Royals

Apr 5, 2026 - MLB

Cleveland Guardians
6 :  5
Chicago Cubs
L W L W L L
Victories

2/6 (33%)

Defeats

4/6 (67%)

Apr 15, 2026 - MLB

St. Louis Cardinals
5 :  3
Cleveland Guardians

Apr 14, 2026 - MLB

St. Louis Cardinals
6 :  5
Cleveland Guardians

Apr 13, 2026 - MLB

St. Louis Cardinals
3 :  9
Cleveland Guardians

Apr 12, 2026 - MLB

Atlanta Braves
13 :  1
Cleveland Guardians

Apr 11, 2026 - MLB

Atlanta Braves
0 :  6
Cleveland Guardians

Apr 10, 2026 - MLB

Atlanta Braves
11 :  5
Cleveland Guardians
Baltimore Orioles
Baltimore Orioles Latest matches
W W L L L W
Victories

3/6 (50%)

Defeats

3/6 (50%)

Apr 17, 2026 - MLB

Cleveland Guardians
4 :  6
Baltimore Orioles

Apr 16, 2026 - MLB

Cleveland Guardians
4 :  2
Baltimore Orioles

Apr 15, 2026 - MLB

Baltimore Orioles
5 :  8
Arizona Diamondbacks

Apr 14, 2026 - MLB

Baltimore Orioles
3 :  4
Arizona Diamondbacks

Apr 13, 2026 - MLB

Baltimore Orioles
9 :  7
Arizona Diamondbacks

Apr 12, 2026 - MLB

Baltimore Orioles
6 :  2
San Francisco Giants
L W W W L L
Victories

3/6 (50%)

Defeats

3/6 (50%)

Apr 15, 2026 - MLB

Baltimore Orioles
5 :  8
Arizona Diamondbacks

Apr 14, 2026 - MLB

Baltimore Orioles
3 :  4
Arizona Diamondbacks

Apr 13, 2026 - MLB

Baltimore Orioles
9 :  7
Arizona Diamondbacks

Apr 12, 2026 - MLB

Baltimore Orioles
6 :  2
San Francisco Giants

Apr 11, 2026 - MLB

Baltimore Orioles
6 :  2
San Francisco Giants

Apr 10, 2026 - MLB

Baltimore Orioles
3 :  6
San Francisco Giants
L W W W L W
Victories

4/6 (67%)

Defeats

2/6 (33%)

Apr 17, 2026 - MLB

Cleveland Guardians
4 :  6
Baltimore Orioles

Apr 16, 2026 - MLB

Cleveland Guardians
4 :  2
Baltimore Orioles

Apr 8, 2026 - MLB

Chicago White Sox
3 :  5
Baltimore Orioles

Apr 7, 2026 - MLB

Chicago White Sox
2 :  4
Baltimore Orioles

Apr 6, 2026 - MLB

Chicago White Sox
1 :  2
Baltimore Orioles

Apr 5, 2026 - MLB

Pittsburgh Pirates
8 :  2
Baltimore Orioles

Cleveland Guardians against Baltimore Orioles : Head to Head (H2H)

Cleveland Guardians

67 %

Baltimore Orioles

33 %

Apr 17, 2026 - MLB

Cleveland Guardians
4 :  6
Baltimore Orioles

Apr 16, 2026 - MLB

Cleveland Guardians
4 :  2
Baltimore Orioles

Jul 24, 2025 - MLB

Cleveland Guardians
3 :  4
Baltimore Orioles

Jul 23, 2025 - MLB

Cleveland Guardians
3 :  2
Baltimore Orioles

Jul 22, 2025 - MLB

Cleveland Guardians
6 :  3
Baltimore Orioles

Jul 21, 2025 - MLB

Cleveland Guardians
10 :  5
Baltimore Orioles

Cleveland Guardians - Baltimore Orioles Key Points

  1. Cleveland leads the all-time series vs. Baltimore, 1166-886-19.
  2. Baltimore is 8-12 ATS (run line) this season; Cleveland is 11-10.
  3. The OVER is 11-9 for Baltimore and 10-11 for Cleveland.
  4. Betting Public: 27% of moneyline tickets and 29% of the handle are on Baltimore.

Our Cleveland Guardians vs Baltimore Orioles Prediction

Neither team has done a great job making contact this season, and I don’t see that improving much when the starters are in the game. However, once Williams comes out, the Orioles could have the advantage, since the Guardians' bullpen has not been good this season (5.55 ERA, 1.44 WHIP, .263 OBA). The Orioles secured the win yesterday against a reliever, and I would not be shocked if that happens again today. Now, the public has bet heavily on the OVER (87% tickets, 83% handle). I don't agree with that call. Kremer and Williams are good enough to keep the score low, but since it is questionable whether the bullpens can do their part, I consider the moneyline a better bet.

Our Baltimore vs. Cleveland Pick: Orioles ML

Prediction:

 

Baltimore ML

+113
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Cleveland Guardians vs Baltimore Orioles Picks