Boston Red Sox vs Baltimore Orioles Prediction & Picks - MLB
USA - MLB
New customers only | Commercial content | 21+ age limit | T&Cs apply
by Lou Aguila | in MLB Picks
The Boston Red Sox will kick off a new series with the Baltimore Orioles as the favorite.
The Red Sox currently trade at -140 moneyline on Caesars Sportsbook, while the Orioles sit at +118 as road underdogs.
Boston is coming into this matchup with a 6-1 record in their last 7 meeting with Baltimore.
Solid pitching has allowed the Red Sox to enjoy this head-to-head dominance over their AL East rivals.
But in the last three meetings, Boston’s offense also exploded.
Powered by a 17-1 rout on April 25, the Red Sox have averaged 8.33 runs per game and stifled the Orioles to 4.6 runs per game over their last three faceoffs.
Boston will start Connelly Early (5-2, 2.95 ERA) in Game 1. Early dazzled in his last start against the Atlanta Braves on May 27. The lefty pitched seven scoreless innings and struck out seven batters to lead Boston to an 8-0 win.
Baltimore will counter with Shane Baz (2-5, 4.48 ERA). After allowing 13 earned runs in his first three starts in May, Baz surrendered a total of two runs in his last two mound appearances.
Boston remains a solid pick to win this game. But with two solid pitchers scheduled to start on Tuesday, backing the Red Sox to win by two runs may not be a good idea.
Limited Offer. Currently at Caesars Sportsbook
Boston Red Sox vs Baltimore Orioles Form
Table
| Teams | Pts | P | W | L |
|---|---|---|---|---|
|
7
|
0.542 | 118 | 64 | 54 |
|
21
|
0.479 | 119 | 57 | 62 |
Boston Red Sox and Baltimore Orioles Latest Matches
3/6 (50%)
3/6 (50%)
May 31, 2026 - MLB
May 30, 2026 - MLB
May 29, 2026 - MLB
May 28, 2026 - MLB
May 27, 2026 - MLB
May 26, 2026 - MLB
1/6 (17%)
5/6 (83%)
May 28, 2026 - MLB
May 27, 2026 - MLB
May 26, 2026 - MLB
May 24, 2026 - MLB
May 23, 2026 - MLB
May 22, 2026 - MLB
5/6 (83%)
1/6 (17%)
May 31, 2026 - MLB
May 30, 2026 - MLB
May 29, 2026 - MLB
May 20, 2026 - MLB
May 19, 2026 - MLB
May 18, 2026 - MLB
4/6 (67%)
2/6 (33%)
May 31, 2026 - MLB
May 30, 2026 - MLB
May 29, 2026 - MLB
May 28, 2026 - MLB
May 27, 2026 - MLB
May 26, 2026 - MLB
4/6 (67%)
2/6 (33%)
May 31, 2026 - MLB
May 30, 2026 - MLB
May 29, 2026 - MLB
May 28, 2026 - MLB
May 27, 2026 - MLB
May 26, 2026 - MLB
1/6 (17%)
5/6 (83%)
May 20, 2026 - MLB
May 19, 2026 - MLB
May 18, 2026 - MLB
May 17, 2026 - MLB
May 16, 2026 - MLB
May 15, 2026 - MLB
Boston Red Sox against Baltimore Orioles : Head to Head (H2H)
67 %
33 %
Apr 26, 2026 - MLB
Apr 25, 2026 - MLB
Apr 24, 2026 - MLB
Mar 1, 2026 - MLB Spring Training
Aug 28, 2025 - MLB
Aug 27, 2025 - MLB
Boston Red Sox - Baltimore Orioles Key Points
- Baltimore is 1-6 SU in its last 7 games against Boston.
- Baltimore is 1-6 SU in its last 7 games on the road.
- Boston is 6-1 in its last 7 meetings with Baltimore
- Connelly Early allowed 2 runs over 6.2 innings in his last start against Baltimore on April 26
Limited Offer. Currently at Caesars Sportsbook
Our Boston Red Sox vs Baltimore Orioles Prediction
Boston will re-assert their dominance over Baltimore to win Game 1.
Early should tame down Baltimore’s offense, who are hitting .221 with 4.0 runs per game against lefties this season. The last time he pitched against Baltimore, Early gave up two runs over 6.2 innings to lead Boston to a 5-3 win on April 26.
Baz can keep Boston’s offense in check in the first half of the match, but the problem reappears once he exits the field. Baltimore’s bullpen has posted a 6.59 ERA over the last five games and 4.71 in the season.
It will be a competitive, defense-oriented ballgame, but Boston should be able to sneak out a close win down the stretch.
Our betting prediction for the Baltimore Orioles vs. the Boston Red Sox: The Red Sox will win.
Caesars Rewards Program

Caesars Sportsbook really spoils new users with an awesome rewards program, making every wager count towards something bigger! Available for users across the country, this program is a bettor's dream. As you enjoy the thrills of sports betting or casino games online, you can earn up to 10 Reward Credits for every $100 wagered on straight bets. And if parlays are more your style, you'll earn up to 20 Reward Credits for every $100 wagered. With Caesars Sportsbook, your bets not only bring the excitement of the game but also the joy of accumulating rewards that enhance your gaming experience. Play now and let Caesars treat you like royalty with each bet you place!
All tips are fully researched and given in good faith, but profits cannot be guaranteed.