Arsenal vs Bayer Leverkusen Prediction & Picks - Champions League

Europe - Champions League

Arsenal
3/17/26 16:00
Bayer Leverkusen

Prediction:

 

Arsenal -1.5.

-118
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 by Carlos Zabala | in Champions League Picks

With a well-taken penalty by Havertz, the German prevented his former team from beating Arsenal in Germany; now the Gunners only need a victory against Bayer Leverkusen to advance to the Champions League quarterfinals. Arsenal had a perfect league campaign; a win on Tuesday would give them their third consecutive quarterfinal appearance. During the league campaign, Arteta's Arsenal even managed to defeat an unbeaten Bayern Munich side in London this season. Therefore, the London club's confidence is brimming, further boosted by their 2-0 Premier League win over Everton at the weekend, putting them closer than ever to their first league title since 2004.

Even so, Bayer Leverkusen is a tough nut to crack, so much so that they came to the Etihad Stadium and surprised everyone by beating Manchester City; they had also previously defeated Benfica in Portugal. Bayer Leverkusen have lost only one of their last 14 matches, but four of their last five were draws, including this past weekend when García's early goal secured a 1-1 draw against Bayern Munich.

Even so, the Champions League round of 16 has become a historical barrier for Bayer Leverkusen, who haven't reached the quarterfinals since 2002. Furthermore, they failed to score in their last three away matches in the round of 16.

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Arsenal vs Bayer Leverkusen Form

Arsenal and Bayer Leverkusen Latest Matches

Arsenal
Arsenal Latest matches
W W W W D W
Victories

5/6 (83%)

Draw

1/6 (17%)

Defeats

0/6 (0%)

Average stats (Last 6 matchs)

2.67 Total goals
67% BTTS
2 Goals scored
0.67 Goals conceded
50% Over 2.5
50% Under 2.5

Mar 14, 2026 - Premier League

Arsenal
2 :  0
Everton

Mar 11, 2026 - Champions League

Bayer Leverkusen
1 :  1
Arsenal

Mar 7, 2026 - FA Cup

Mansfield Town
1 :  2
Arsenal

Mar 4, 2026 - Premier League

Brighton
0 :  1
Arsenal

Mar 1, 2026 - Premier League

Arsenal
2 :  1
Chelsea

Feb 22, 2026 - Premier League

Tottenham
1 :  4
Arsenal
W W W W W W
Victories

6/6 (100%)

Draw

0/6 (0%)

Defeats

0/6 (0%)

Average stats (Last 6 matchs)

3 Total goals
33% BTTS
2.5 Goals scored
0.5 Goals conceded
67% Over 2.5
33% Under 2.5

Mar 14, 2026 - Premier League

Arsenal
2 :  0
Everton

Mar 1, 2026 - Premier League

Arsenal
2 :  1
Chelsea

Feb 15, 2026 - FA Cup

Arsenal
4 :  0
Wigan

Feb 7, 2026 - Premier League

Arsenal
3 :  0
Sunderland

Feb 3, 2026 - Carabao Cup

Arsenal
1 :  0
Chelsea

Jan 28, 2026 - Champions League

Arsenal
3 :  2
Kairat Almaty
D D W W W D
Victories

3/6 (50%)

Draw

3/6 (50%)

Defeats

0/6 (0%)

Average stats (Last 6 matchs)

2.83 Total goals
83% BTTS
1.83 Goals scored
1 Goals conceded
50% Over 2.5
50% Under 2.5

Mar 11, 2026 - Champions League

Bayer Leverkusen
1 :  1
Arsenal

Mar 7, 2026 - FA Cup

Mansfield Town
1 :  2
Arsenal

Mar 4, 2026 - Premier League

Brighton
0 :  1
Arsenal

Feb 22, 2026 - Premier League

Tottenham
1 :  4
Arsenal

Feb 18, 2026 - Premier League

Wolves
2 :  2
Arsenal

Feb 12, 2026 - Premier League

Brentford
1 :  1
Arsenal
Bayer Leverkusen
Bayer Leverkusen Latest matches
D D W D D D
Victories

1/6 (17%)

Draw

5/6 (83%)

Defeats

0/6 (0%)

Average stats (Last 6 matchs)

2.17 Total goals
67% BTTS
1.17 Goals scored
1 Goals conceded
17% Over 2.5
83% Under 2.5

Mar 14, 2026 - Bundesliga

Bayer Leverkusen
1 :  1
Bayern Munich

Mar 11, 2026 - Champions League

Bayer Leverkusen
1 :  1
Arsenal

Mar 7, 2026 - Bundesliga

Freiburg
3 :  3
Bayer Leverkusen

Mar 4, 2026 - Bundesliga

Hamburg
0 :  1
Bayer Leverkusen

Feb 28, 2026 - Bundesliga

Bayer Leverkusen
1 :  1
1 Fsv Mainz 05

Feb 24, 2026 - Champions League

Bayer Leverkusen
0 :  0
Olympiacos
W W D D D D
Victories

2/6 (33%)

Draw

4/6 (67%)

Defeats

0/6 (0%)

Average stats (Last 6 matchs)

2.17 Total goals
50% BTTS
1.67 Goals scored
0.5 Goals conceded
33% Over 2.5
67% Under 2.5

Mar 14, 2026 - Bundesliga

Bayer Leverkusen
1 :  1
Bayern Munich

Mar 11, 2026 - Champions League

Bayer Leverkusen
1 :  1
Arsenal

Feb 28, 2026 - Bundesliga

Bayer Leverkusen
1 :  1
1 Fsv Mainz 05

Feb 24, 2026 - Champions League

Bayer Leverkusen
0 :  0
Olympiacos

Feb 14, 2026 - Bundesliga

Bayer Leverkusen
4 :  0
St. Pauli

Feb 3, 2026 - DFB Pokal

Bayer Leverkusen
3 :  0
St. Pauli
W D W L W D
Victories

3/6 (50%)

Draw

2/6 (33%)

Defeats

1/6 (17%)

Average stats (Last 6 matchs)

2.67 Total goals
50% BTTS
1.67 Goals scored
1 Goals conceded
33% Over 2.5
67% Under 2.5

Mar 7, 2026 - Bundesliga

Freiburg
3 :  3
Bayer Leverkusen

Mar 4, 2026 - Bundesliga

Hamburg
0 :  1
Bayer Leverkusen

Feb 21, 2026 - Bundesliga

Union Berlin
1 :  0
Bayer Leverkusen

Feb 18, 2026 - Champions League

Olympiacos
0 :  2
Bayer Leverkusen

Feb 7, 2026 - Bundesliga

Mönchengladbach
1 :  1
Bayer Leverkusen

Jan 31, 2026 - Bundesliga

Eintracht Frankfurt
1 :  3
Bayer Leverkusen

Arsenal against Bayer Leverkusen : Head to Head (H2H)

Arsenal

50 %

Draw

50 %

Bayer Leverkusen

0 %

Average stats (last H2H results)

3.5
Total goals
100%
BTTS
2.5
Goals scored
1
Goals conceded
50%
Over 2.5
50%
Under 2.5

Mar 11, 2026 - Champions League

Bayer Leverkusen
1 :  1
Arsenal

Aug 7, 2024 - Clubs Friendlies

Arsenal
4 :  1
Bayer Leverkusen

Arsenal - Bayer Leverkusen: Form Analysis

With goals from Gyökeres and Dowman in the 97th minute, Arteta's Arsenal defeated Everton at the Emirates Stadium in a match on Matchday 30. Known for faltering when it matters most, this time the more experienced Gunners seem determined to avoid a collapse in the final stretch of the season.

The Premier League title is practically a foregone conclusion with odds of -1429 to win it, but at +250 odds they are also the favorite to win this Champions League.

With 10 wins, Arsenal have now gone 13 consecutive matches without defeat; they have won 17 out of 20 European knockout ties in which they didn't lose the first leg away from home, and Arsenal have never lost to Leverkusen in their history.

Bayer Leverkusen's victory halted their historically poor run of results against English opposition in Europe; the Aspirins have lost 8 of their last 11 matches on English soil.

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Arsenal against Bayer Leverkusen Lineups: Starting 11

Arsenal

Formation : 4 - 2 - 3 - 1

1
D. Raya
4
B. White
2
W. Saliba
6
G. Magalhaes
5
P. Hincapie
41
D. Rice
36
M. Zubimendi
7
B. Saka
10
E. Eze
19
L. Trossard
14
V. Gyokeres
35
C. Kofane
11
M. Terrier
30
I. Maza
20
A. Grimaldo
24
A. Garcia
25
E. Palacios
19
E. Poku
12
E. Tapsoba
8
R. Andrich
4
J. Quansah
28
J. Blaswich

Formation : 3 - 4 - 2 - 1

Bayer Leverkusen

Substitutes

Arsenal
Arsenal
Goalkeeper

K. Ranson

K. Arrizabalaga

Defender

R. Calafiori

C. Mosquera

B. White 69'

Midfielder

M. Dowman

C. Norgaard

M. Zubimendi 68'

M. Lewis-Skelly

V. Gyokeres 90'

Forward

G. Martinelli

L. Trossard 69'

N. Madueke

K. Havertz

E. Eze 69'

G. Jesus

Bayer Leverkusen
Bayer Leverkusen
Goalkeeper

J. Omlin

N. Lomb

Defender

T. Oermann

Midfielder

M. Tillman

M. Terrier 60'

E. Fernandez

R. Andrich 83'

A. Tape

J. Hofmann

Forward

M. Culbreath

E. Poku 60'

P. Schick

E. Palacios 70'

Missing players

Arsenal
Arsenal
Defender

J. Timber

Midfielder

M. Merino

Bayer Leverkusen
Bayer Leverkusen
Goalkeeper

M. Flekken

Defender

L. Vazquez

L. Bade

Arthur

Forward

E. Ben Seghir

Arsenal & Bayer Leverkusen Squad Analysis

Havertz, despite scoring the first-leg goal, wasn't particularly effective against Everton at the weekend, so Arteta might turn to Gyokeres, the striker Arsenal spent a fortune on, to lead the Gunners' attack. Behind the Swede, Arteta would adjust his lineup to allow the two dribblers, Saka and Madueke, to play on either flank. Against Everton, in the last match, the center-backs played flawlessly, Gabriel, but especially Saliba, who won six aerial duels.

Arteta has a big choice to make for his front man, with Havertz and Gyokeres both fit.

Due to the postponement, Aleix Garcia could very well miss the second leg for Leverkusen; Grimaldo, Maza, Terrier, and Kofane are then likely to lead the Bundesliga club's attack.

Most goals and assists

CD Huachipato Arsenal
CD Huachipato Bayer Leverkusen
Top Goalscorer
Brazil G. Martinelli (6 Goals)
Top Goalscorer
Spain A. Grimaldo (4 Goals) Czech Republic P. Schick (4 Goals)
Best assists
Belgium L. Trossard (5 Assists)
Best assists
Spain A. Grimaldo (3 Assists)

Arsenal - Bayer Leverkusen Key Points

  1. Bayer Leverkusen has only scored five Champions League goals in the first halves this season
  2. Arsenal controlled 64% of possession in their last league match
  3. Arsenal had eight corner kicks in their previous game
  4. Arsenal held Bayer Leverkusen to an xG of 0.85 in the first leg
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Our Arsenal vs Bayer Leverkusen Prediction

Arsenal have now won six consecutive matches at the Emirates Stadium in all competitions; recently, in London, Wigan in the FA Cup and Brighton and Everton in the Premier League failed to score a single goal against the Gunners. This is certainly not good news for Bayer Leverkusen.

Although Arsenal will be without Ødegaard and Merino, the London side boasts a deep squad, and among their other stars, Zubimendi and Rice will be playing on Tuesday, while the list of confirmed or doubtful absences for Bayer Leverkusen's Champions League game has grown to eight.

Our prediction for Arsenal vs Bayer Leverkusen is: Arsenal -1.5.

Prediction:

 

Arsenal -1.5.

-118
$350 offered for betting!

Arsenal vs Bayer Leverkusen - Other Interesting Picks

Viktor Gyokeres to score or assist

Odds -145
Gyökeres played just 30 minutes against Everton, but the agile Swede looked sharp on the pitch and opened the scoring for the Gunners. FanDuel is offering fair odds on him to score again on Tuesday.
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Over 2.5

Odds -166
A safer bet, however, is on over 2.5 goals. Champions League knockout second legs tend to be open and decisive in the closing stages, with the desperation of the home side and Leverkusen's high-speed passing game, but Arsenal's quick transitions from defense to attack could also produce more goals in the final half-hour.
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Arsenal win the match

Odds -370

Although Arsenal narrowly avoided defeat in the first leg in Germany and may be at a disadvantage as the favorite, facing the pressure of being “expected” to advance to the quarterfinals, the fact is that the British side has what it takes to reach the next round.

We’re confident that Arteta’s team will capitalize on home-field advantage and defeat Leverkusen in London. 

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All tips are fully researched and given in good faith, but profits cannot be guaranteed.

Arsenal vs Bayer Leverkusen Picks