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by Travis Pulver in NCAA Picks
The Arizona Wildcats will travel to Iowa to face the No. 14 Iowa State Cyclones (4-0) at Jack Trice Stadium in Ames, IA. Kickoff for this Big 12 battle of undefeated teams is scheduled for 7 p.m. EST. The game will be broadcast on ESPN.
Expectations were certainly high for the Cyclones coming into the season after Iowa State made it to the Big 12 title game last season and beat Miami in the Pop-Tarts Bowl. So far, they have lived up to them. Known for often being one of the stronger defensive teams in the nation, the Cyclones have been picking it up on offense behind the leadership of junior quarterback Rocco Becht. Becht has completed 65% of his passes so far this season with seven touchdown passes and just one interception. As for Arizona, the Wildcats go off to a solid start this season with a 40-6 win over Hawaii, followed by a dominant 48-3 showing against Weber State. They last played against Kansas State a couple of weeks ago. They used a strong run game and dominant defensive play to secure a 23-17 win with Ismal Mahdi running for 189 yards and quarterback Noah Fifita adding another 48 yards and two touchdowns on the ground.
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Arizona Wildcats vs Iowa State Cyclones Form
Table
| Teams | % | P | W | D | L |
|---|---|---|---|---|---|
|
4
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1 | 1 | 1 | 0 | 0 |
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6
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1 | 1 | 1 | 0 | 0 |
Arizona Wildcats and Iowa State Cyclones Latest Matches
4/6 (67%)
0/6 (0%)
2/6 (33%)
Sep 12, 2025 - NCAA
Sep 6, 2025 - NCAA
Aug 30, 2025 - NCAA
Nov 30, 2024 - NCAA
Nov 23, 2024 - NCAA
Nov 15, 2024 - NCAA
4/6 (67%)
0/6 (0%)
2/6 (33%)
Sep 12, 2025 - NCAA
Sep 6, 2025 - NCAA
Aug 30, 2025 - NCAA
Nov 30, 2024 - NCAA
Nov 15, 2024 - NCAA
Oct 26, 2024 - NCAA
1/5 (20%)
0/5 (0%)
4/5 (80%)
Nov 23, 2024 - NCAA
Nov 2, 2024 - NCAA
Oct 12, 2024 - NCAA
Sep 28, 2024 - NCAA
Sep 13, 2024 - NCAA
5/6 (83%)
0/6 (0%)
1/6 (17%)
Sep 13, 2025 - NCAA
Sep 6, 2025 - NCAA
Aug 30, 2025 - NCAA
Aug 23, 2025 - NCAA
Dec 28, 2024 - NCAA Division I, FBS, Playoffs
Dec 7, 2024 - NCAA
5/6 (83%)
0/6 (0%)
1/6 (17%)
Sep 6, 2025 - NCAA
Aug 30, 2025 - NCAA
Nov 30, 2024 - NCAA
Nov 16, 2024 - NCAA
Nov 2, 2024 - NCAA
Oct 19, 2024 - NCAA
4/6 (67%)
0/6 (0%)
2/6 (33%)
Sep 13, 2025 - NCAA
Aug 23, 2025 - NCAA
Dec 28, 2024 - NCAA Division I, FBS, Playoffs
Dec 7, 2024 - NCAA
Nov 23, 2024 - NCAA
Nov 9, 2024 - NCAA
Arizona Wildcats - Iowa State Cyclones Key Points
- This game will be just the second between Iowa State and Arizona; the Wildcats won the first last season 45-19.
- Since 2020, Arizona is 4-16 when a road underdog.
- Since 2020, Iowa State is 22-6 when favored at home.
- Betting Public: 59% of TOTAL tickets and 54% of the handle are on the OVER.
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Our Arizona Wildcats vs Iowa State Cyclones Prediction
These two teams are really similar. Both have solid offenses led by good, capable quarterbacks and strong run games. The defense has played well for each, and they both had narrow wins against Kansas State (who is having a down year). With teams that are so similar. I’d expect a good, hard-fought, entertaining football game to watch. But from a betting perspective, if it’s as close a game as I expect it to be…
Our Arizona vs. Iowa State: Arizona +6.5
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All tips are fully researched and given in good faith, but profits cannot be guaranteed.
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