Pittsburgh Pirates vs Arizona Diamondbacks Prediction & Picks - MLB

USA - MLB

Pittsburgh Pirates
7/25/25 18:40
Arizona Diamondbacks

Prediction:

 

Arizona Diamondbacks win both halves

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 by Erik Gibbs | in MLB Picks

The Arizona Diamondbacks travel to PNC Park tonight to open a three-game series against the Pittsburgh Pirates, with both teams aiming to build momentum as the season heads into the late summer stretch. Arizona is fresh off a tough road swing in which they followed a series win over the Cardinals with a disappointing series loss to the Houston Astros.

Currently sitting fourth in the National League West with a 50-53 record, the Diamondbacks are four games behind third place. They face a critical stretch that could determine their direction at the upcoming trade deadline on July 31.

Pittsburgh, on the other hand, sits in last place in the NL Central and is currently 10 games behind the fourth-place Reds. Despite their position in the standings, the Pirates are riding high after sweeping the Detroit Tigers in a three-game set, offering a bit of hope to a team that has struggled with consistency throughout the season.

That momentum will be tested immediately, however, as they welcome a motivated Arizona team looking to climb back to .500.

Pittsburgh Pirates vs Arizona Diamondbacks Form

Table

Teams Pts P W L
18 Arizona Diamondbacks
0.494 162 80 82
26 Pittsburgh Pirates
0.438 162 71 91

Pittsburgh Pirates and Arizona Diamondbacks Latest Matches

Pittsburgh Pirates
Pittsburgh Pirates Latest matches
L L L W W W
Victories

3/6 (50%)

Defeats

3/6 (50%)

Jul 23, 2025 - MLB

Pittsburgh Pirates
6 :  1
Detroit Tigers

Jul 22, 2025 - MLB

Pittsburgh Pirates
8 :  5
Detroit Tigers

Jul 21, 2025 - MLB

Pittsburgh Pirates
3 :  0
Detroit Tigers

Jul 20, 2025 - MLB

Pittsburgh Pirates
2 :  7
Chicago White Sox

Jul 19, 2025 - MLB

Pittsburgh Pirates
4 :  10
Chicago White Sox

Jul 18, 2025 - MLB

Pittsburgh Pirates
1 :  10
Chicago White Sox
L L L W W W
Victories

3/6 (50%)

Defeats

3/6 (50%)

Jul 23, 2025 - MLB

Pittsburgh Pirates
6 :  1
Detroit Tigers

Jul 22, 2025 - MLB

Pittsburgh Pirates
8 :  5
Detroit Tigers

Jul 21, 2025 - MLB

Pittsburgh Pirates
3 :  0
Detroit Tigers

Jul 20, 2025 - MLB

Pittsburgh Pirates
2 :  7
Chicago White Sox

Jul 19, 2025 - MLB

Pittsburgh Pirates
4 :  10
Chicago White Sox

Jul 18, 2025 - MLB

Pittsburgh Pirates
1 :  10
Chicago White Sox
L L L L L W
Victories

1/6 (17%)

Defeats

5/6 (83%)

Jul 13, 2025 - MLB

Minnesota Twins
1 :  2
Pittsburgh Pirates

Jul 12, 2025 - MLB

Minnesota Twins
12 :  4
Pittsburgh Pirates

Jul 11, 2025 - MLB

Minnesota Twins
2 :  1
Pittsburgh Pirates

Jul 9, 2025 - MLB

Kansas City Royals
4 :  3
Pittsburgh Pirates

Jul 8, 2025 - MLB

Kansas City Royals
4 :  3
Pittsburgh Pirates

Jul 7, 2025 - MLB

Kansas City Royals
9 :  3
Pittsburgh Pirates
Arizona Diamondbacks
Arizona Diamondbacks Latest matches
W W W L L L
Victories

3/6 (50%)

Defeats

3/6 (50%)

Jul 23, 2025 - MLB

Arizona Diamondbacks
3 :  4
Houston Astros

Jul 22, 2025 - MLB

Arizona Diamondbacks
1 :  3
Houston Astros

Jul 21, 2025 - MLB

Arizona Diamondbacks
3 :  6
Houston Astros

Jul 20, 2025 - MLB

Arizona Diamondbacks
5 :  3
St. Louis Cardinals

Jul 19, 2025 - MLB

Arizona Diamondbacks
10 :  1
St. Louis Cardinals

Jul 18, 2025 - MLB

Arizona Diamondbacks
7 :  3
St. Louis Cardinals
W W W L L L
Victories

3/6 (50%)

Defeats

3/6 (50%)

Jul 23, 2025 - MLB

Arizona Diamondbacks
3 :  4
Houston Astros

Jul 22, 2025 - MLB

Arizona Diamondbacks
1 :  3
Houston Astros

Jul 21, 2025 - MLB

Arizona Diamondbacks
3 :  6
Houston Astros

Jul 20, 2025 - MLB

Arizona Diamondbacks
5 :  3
St. Louis Cardinals

Jul 19, 2025 - MLB

Arizona Diamondbacks
10 :  1
St. Louis Cardinals

Jul 18, 2025 - MLB

Arizona Diamondbacks
7 :  3
St. Louis Cardinals
L W L L L W
Victories

2/6 (33%)

Defeats

4/6 (67%)

Jul 13, 2025 - MLB

Los Angeles Angels
1 :  5
Arizona Diamondbacks

Jul 12, 2025 - MLB

Los Angeles Angels
10 :  5
Arizona Diamondbacks

Jul 11, 2025 - MLB

Los Angeles Angels
6 :  5
Arizona Diamondbacks

Jul 10, 2025 - MLB

San Diego Padres
4 :  3
Arizona Diamondbacks

Jul 9, 2025 - MLB

San Diego Padres
2 :  8
Arizona Diamondbacks

Jul 8, 2025 - MLB

San Diego Padres
1 :  0
Arizona Diamondbacks

Pittsburgh Pirates against Arizona Diamondbacks : Head to Head (H2H)

Pittsburgh Pirates

40 %

Arizona Diamondbacks

60 %

May 27, 2025 - MLB

Arizona Diamondbacks
6 :  9
Pittsburgh Pirates

May 26, 2025 - MLB

Arizona Diamondbacks
5 :  0
Pittsburgh Pirates

Aug 4, 2024 - MLB

Pittsburgh Pirates
5 :  6
Arizona Diamondbacks

Aug 3, 2024 - MLB

Pittsburgh Pirates
4 :  2
Arizona Diamondbacks

Aug 2, 2024 - MLB

Pittsburgh Pirates
8 :  9
Arizona Diamondbacks

Pittsburgh Pirates - Arizona Diamondbacks Key Points

  1. The Diamondbacks are 16-2 in their last 18 games vs. NL Central teams after a home loss
  2. The Pirates are 0-7 in their last 7 home games vs.NL West teams
  3. The Diamondbacks have covered the run line in their last 5 night games vs. the Pirates after a home loss
  4. The Pirates have failed to cover the run line in 5 of their last 6 games at PNC Park vs. teams with a losing record

Our Pittsburgh Pirates vs Arizona Diamondbacks Prediction

Tonight’s pitching matchup may give the edge to the visiting Diamondbacks. Ryne Nelson is set to take the mound for Arizona and has delivered solid performances throughout the year. Nelson’s ability to limit base runners and avoid big innings could be key against a Pittsburgh lineup that has struggled to generate offense for most of the season. If he can stay in rhythm, Nelson may give Arizona the upper hand in a game that could swing on pitching efficiency.

On the flip side, Mike Burrows will toe the rubber for the Pirates. Burrows has experienced a rocky season, with command issues and poor results in matchups against aggressive lineups like Arizona’s. The Diamondbacks' bats have had success against him in the past, and with hitters like Ketel Marte and Christian Walker capable of changing the game with one swing, Burrows will need to be sharp early to avoid falling behind.

With Arizona trying to avoid becoming sellers at the deadline and the Pirates hoping to turn recent success into a more sustained run, tonight's game could set the tone for the rest of the series. A win for the Diamondbacks would not only give them a jump on the series but also help keep them within striking distance in a crowded NL Wild Card race. Our prediction for Pittsburgh Pirates vs. Arizona Diamondbacks: Diamondbacks to win.

Prediction:

 

Arizona Diamondbacks win both halves

-124
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Pittsburgh Pirates vs Arizona Diamondbacks Picks