Chicago Cubs vs Arizona Diamondbacks Prediction & Picks - MLB
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by Lou Aguila | in MLB Picks
Despite pitting two exceptional starters against each other on Friday, the Over 7.5 runs remains an appealing pick because of how strong the offense has turned out this season for the Chicago Cubs and the Arizona Diamondbacks.
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The Arizona Diamondbacks have split their last four games, keeping them two games above .500 at 16-14. The D-Backs remain one of the worst pitching teams in baseball, posting a 5.12 ERA and 1.38 WHIP. Their offensive numbers are a little above league average at 4.8 runs per game on a .250 BA, but again, they are losing a ton of winnable games because of bad pitching.
The Cubs arrested their three-game losing streak with back-to-back wins over the San Diego Padres. The Cubs (19-12) still trail Cincinnati (20-11) in the NL Central standings, but this team is certainly oozing with potential because of their top-tier offense that produces 5.6 runs per game this season.
Starting Pitchers: Diamondbacks Zac Gallen (1-1, 3.14 ERA) vs. Cubs Collin Rea (3-1, 4.61 ERA)
Gallen is coming off a shutout stint (0 runs over 3 innings) against the Padres on April 25, but he gave up 6 earned runs the last time he pitched against the Cubs on April 19, 2025.
Rea surrendered 6 runs in his last start against the LA Dodgers on April 25. On the other hand, he has decent numbers (2.7 ER over 4.2 IP) across his last three starts against the D-backs.
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Chicago Cubs vs Arizona Diamondbacks Form
Table
| Teams | Pts | P | W | L |
|---|---|---|---|---|
|
7
|
0.549 | 162 | 89 | 73 |
|
10
|
0.531 | 162 | 86 | 76 |
Chicago Cubs and Arizona Diamondbacks Latest Matches
3/6 (50%)
3/6 (50%)
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6/6 (100%)
0/6 (0%)
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3/6 (50%)
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2/6 (33%)
4/6 (67%)
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2/6 (33%)
4/6 (67%)
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3/6 (50%)
3/6 (50%)
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Chicago Cubs against Arizona Diamondbacks : Head to Head (H2H)
67 %
33 %
Mar 18, 2026 - MLB Spring Training
Mar 5, 2026 - MLB Spring Training
Apr 19, 2025 - MLB
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Chicago Cubs - Arizona Diamondbacks Key Points
- The total has gone OVER in 8 of Chicago Cubs' last 9 games.
- The total has gone OVER in 4 of Chicago Cubs' last 5 games against an opponent in the National League.
- The total has gone OVER in 8 of Arizona's last 12 games.
- The total has gone OVER in 4 of Arizona's last 6 games on the road.
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Our Chicago Cubs vs Arizona Diamondbacks Prediction
Back the total to go OVER at 7.5 runs. Zach Gallen and Collin Rea are strong pitchers for their respective squads, but they have been too erratic this season to be trusted in holding the other teams from scoring multiple runs. More so, the Cubs and the D-Backs continue to produce above-average numbers at the plate over their last five games. Chicago averages 4.8 runs per game, while Arizona averages 5.1 runs per contest over this five-game stretch.
Recent trends also favor the OVER. The total has gone OVER in 4 of Arizona's last 6 road games and 8 of the Chicago Cubs' last 9 games.
Our betting prediction for the Arizona Diamondbacks vs. the Chicago Cubs: The Over 7.5 Runs
All tips are fully researched and given in good faith, but profits cannot be guaranteed.
