Baltimore Orioles vs Arizona Diamondbacks Prediction & Picks - MLB

Prediction published on 4/15/26, 8:52 AM  by Travis Pulver | Modified on 4/17/26 at 5:45 AM in MLB Picks

The Baltimore Orioles (9-8, 6-5 Home) will try to get back on the right side of the scoreboard Wednesday afternoon when they host the Arizona Diamondbacks in Game Three of a mid-week, three-game series. First Pitch for this matchup is scheduled for 12:35 p.m. EST at Oriole Park at Camden Yards in Baltimore, MD, with coverage provided by MLB.TV.

Arizona got out to a 7-1 lead through the top of the 6th inning in Game One on Monday. But the Orioles began the comeback with a five-run inning in the bottom of the 6th to make the score 7-6, D-Backs. Then they tacked on two more in the 7th and the final run of the game in the 8th to seal the come-from-behind win, 9-7. Tuesday’s game wasn’t nearly as dramatic. Baltimore took an early 2-0 lead through three innings, but a four-run fifth inning put the Orioles up 4-2, a lead they’d never relinquish.

Eduardo Rodriguez is scheduled to get the start for the Diamondbacks. Through three starts, he is 1-0 with a .50 ERA and a 1.0 WHIP. He gave up one run in his first start and another in his last start—that’s it, and both were home runs. Kyle Bradish will get the start for the Orioles. He is 1-2 with a 5.27 ERA and a 1.68 WHIP.