Alex De Minaur vs Reilly Opelka Prediction & Picks - ATP Cincinnati Open

ATP - ATP Cincinnati Open

ATP 7 Australia
Alex De Minaur
8/10/25 11:00
ATP 62 USA
Reilly Opelka

Prediction:

 

Alex De Minaur -3.5 Games

-105
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 by Lou Aguila | in ATP Cincinnati Open Picks

Reilly Opelka of the United States braces up for a tough second-round battle with the world’s No.8 Alex De Minaur of Australia at the 2025 Cincinnati Open on Sunday.

Opelka will be trying to earn his first win over De Minaur after going 0-5 in their first five matchups. Opelka advanced to the second round in Cincy after grinding out a 7-5 7-6(3) victory over Hugo Dellien of Bolivia in the opening round. Opelka weaponized his massive serves to full extent, capturing 27 points off the first serves and 26 more on the second while firing 15 aces. He also broke a serve to secure a whisker of an edge against the feisty Bolivian.

De Minaur has achieved strong results in his last two tournaments, reaching the quarterfinal at the 2025 Canadian Open and capturing the Mubadala Citi Washington Open two weeks earlier. The Australian had strung up eight wins in a row before his winning run came to an end at the hands of eventual Canadian Open champion Ben Shelton in the last eight, 3-6, 4-6.

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Alex De Minaur vs Reilly Opelka Form

Alex De Minaur and Reilly Opelka Latest Matches

Alex De Minaur Latest matches
W W W W W L
Victories

5/6 (83%)

Defeats

1/6 (17%)

Aug 5, 2025 - ATP Toronto

Alex De Minaur
0 :  2
Ben Shelton

Aug 3, 2025 - ATP Toronto

Frances Tiafoe
1 :  2
Alex De Minaur

Aug 2, 2025 - ATP Toronto

Christopher O'Connell
withdraw
Alex De Minaur

Jul 30, 2025 - ATP Toronto

Francisco Comesana
0 :  2
Alex De Minaur

Jul 27, 2025 - ATP Washington Citi Open

Alejandro Davidovich Fokina
1 :  2
Alex De Minaur

Jul 26, 2025 - ATP Washington Citi Open

Corentin Moutet
0 :  2
Alex De Minaur
Reilly Opelka Latest matches
W L W W L W
Victories

4/6 (67%)

Defeats

2/6 (33%)

Aug 8, 2025 - ATP Cincinnati Open

Hugo Dellien
0 :  2
Reilly Opelka

Jul 31, 2025 - ATP Toronto

Learner Tien
2 :  0
Reilly Opelka

Jul 29, 2025 - ATP Toronto

Reilly Opelka
2 :  1
Tomas Machac

Jul 27, 2025 - ATP Toronto

Sebastian Ofner
0 :  2
Reilly Opelka

Jul 23, 2025 - ATP Washington Citi Open

Daniil Medvedev
2 :  1
Reilly Opelka

Jul 21, 2025 - ATP Washington Citi Open

Reilly Opelka
2 :  1
Murphy Cassone

Alex De Minaur against Reilly Opelka : Head to Head (H2H)

Oct 26, 2019 - Swiss Indoors ATP Basel

Reilly Opelka
1 :  2
Alex De Minaur
Compare Alex De Minaur and Reilly Opelka with our comparison tool.

Alex De Minaur - Reilly Opelka Key Points

  1. Reilly Opelka defeated Hugo Dellien 7-5 7-6(3) in the first round of the 2025 Cincinnati Open.
  2. Reilly Opelka is 0-5 in his head-to-head series with Alex De Minaur.
  3. Alex De Minaur is 8-1 since the start of the North American hard-court season.
  4. Alex De Minaur won the 2025 Washington DC Open.
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Our Alex De Minaur vs Reilly Opelka Prediction

Prediction: Alex De Minaur will breeze through to the next round with another surgical win over Reilly Opelka, improving his head-to-head record over the American to 6-0, and in the process, covering a -3.5-game handicap.

De Minaur is enjoying a resurgence in form in the past three weeks, which has seen the Australian win an ATP-500 level tournament in Washington and reach the quarterfinal of an ATP-1000 level event in Canada, losing only to the eventual winner, Ben Shelton.

Opelka carries a 13-8 record on the hard court this year, but hasn’t gotten that many opportunities to play a top-10 player. He’s 1-1 against the ATP Top-10 this year, but only 6-9 in second-round matches in 2025.

De Minaur emerges as a firm bet to cover because of his superior head-to-head record over Opelka and a formidable form that makes him one of the dark-horse contenders in Cincinnati.

Our betting prediction for Reilly Opelka vs. Alex De Minaur: Alex De Minaur -3.5 Games.

Prediction:

 

Alex De Minaur -3.5 Games

-105
$300+ offered for betting!

All tips are fully researched and given in good faith, but profits cannot be guaranteed.

Alex De Minaur vs Reilly Opelka Picks