Alabama Crimson Tide vs Vanderbilt Commodores Prediction & Picks - NCAA

USA - NCAA

Alabama Crimson Tide
10/4/25 15:30
Vanderbilt Commodores

Prediction:

 

Vanderbilt Commodores +10.5

-112
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 by Matt Lowrimore | in NCAA Picks

One of the most interesting games on the Week 6 Saturday college football slate will see the 16th-ranked Vanderbilt Commodores take 10th-ranked Alabama Crimson Tide in the SEC. Let’s take a look at the match statistics and predictions for this game between the Commodores and the Crimson Tide.

Vanderbilt enters this game with a record of 5-0 and 1-0 in the SEC. The Commodores most recently beat the Utah State Aggies in Week 5 by a score of 55-35. Vanderbilt’s offense had a total of 546 yards, while its defense allowed 393 yards. Quarterback Diego Pavia threw for 321 yards, five touchdowns, and one interception, while also leading the team in rushing with 79 yards and one touchdown.

As for Alabama, they enter this game with a record of 3-1 and 1-0 in the SEC. The Crimson Tide most recently beat the Georgia Bulldogs in Week 5 by a score of 24-21. Alabama’s offense had a total of 397 yards, while its defense allowed 357 yards. Quarterback Ty Simpson threw for 276 yards and two touchdowns, while Jam Miller led the team in rushing with 46 yards.

Alabama Crimson Tide vs Vanderbilt Commodores Form

Table

Alabama Crimson Tide and Vanderbilt Commodores Latest Matches

Alabama Crimson Tide
Alabama Crimson Tide Latest matches
W W L W W W
Victories

5/6 (83%)

Defeats

1/6 (17%)

Sep 27, 2025 - NCAA

Georgia Bulldogs
21 :  24
Alabama Crimson Tide

Sep 13, 2025 - NCAA

Alabama Crimson Tide
38 :  14
Wisconsin Badgers

Sep 6, 2025 - NCAA

Alabama Crimson Tide
73 :  0
Louisiana-Monroe Warhawks

Aug 30, 2025 - NCAA

Florida State Seminoles
31 :  17
Alabama Crimson Tide

Sep 28, 2024 - NCAA

Alabama Crimson Tide
41 :  34
Georgia Bulldogs

Sep 14, 2024 - NCAA

Wisconsin Badgers
10 :  42
Alabama Crimson Tide
W W W W
Victories

4/4 (100%)

Defeats

0/4 (0%)

Sep 13, 2025 - NCAA

Alabama Crimson Tide
38 :  14
Wisconsin Badgers

Sep 6, 2025 - NCAA

Alabama Crimson Tide
73 :  0
Louisiana-Monroe Warhawks

Sep 28, 2024 - NCAA

Alabama Crimson Tide
41 :  34
Georgia Bulldogs

Sep 7, 2024 - NCAA

Alabama Crimson Tide
42 :  16
South Florida Bulls
W L W
Victories

2/3 (67%)

Defeats

1/3 (33%)

Sep 27, 2025 - NCAA

Georgia Bulldogs
21 :  24
Alabama Crimson Tide

Aug 30, 2025 - NCAA

Florida State Seminoles
31 :  17
Alabama Crimson Tide

Sep 14, 2024 - NCAA

Wisconsin Badgers
10 :  42
Alabama Crimson Tide
Vanderbilt Commodores
Vanderbilt Commodores Latest matches
W W W W W W
Victories

6/6 (100%)

Defeats

0/6 (0%)

Sep 27, 2025 - NCAA

Vanderbilt Commodores
55 :  35
Utah State Aggies

Sep 20, 2025 - NCAA

Vanderbilt Commodores
70 :  21
Georgia State Panthers

Sep 13, 2025 - NCAA

South Carolina Gamecocks
7 :  31
Vanderbilt Commodores

Sep 6, 2025 - NCAA

Virginia Tech Hokies
20 :  44
Vanderbilt Commodores

Aug 30, 2025 - NCAA

Vanderbilt Commodores
45 :  3
Charleston Southern Buccaneers

Oct 19, 2024 - NCAA

Vanderbilt Commodores
24 :  14
Ball State Cardinals
W W W W
Victories

4/4 (100%)

Defeats

0/4 (0%)

Sep 27, 2025 - NCAA

Vanderbilt Commodores
55 :  35
Utah State Aggies

Sep 20, 2025 - NCAA

Vanderbilt Commodores
70 :  21
Georgia State Panthers

Aug 30, 2025 - NCAA

Vanderbilt Commodores
45 :  3
Charleston Southern Buccaneers

Oct 19, 2024 - NCAA

Vanderbilt Commodores
24 :  14
Ball State Cardinals
L W W
Victories

2/3 (67%)

Defeats

1/3 (33%)

Sep 13, 2025 - NCAA

South Carolina Gamecocks
7 :  31
Vanderbilt Commodores

Sep 6, 2025 - NCAA

Virginia Tech Hokies
20 :  44
Vanderbilt Commodores

Sep 21, 2024 - NCAA

Missouri Tigers
30 :  27
Vanderbilt Commodores

Alabama Crimson Tide - Vanderbilt Commodores Key Points

  1. Vanderbilt is 4-1 ATS this season
  2. Vanderbilt is averaging 55.0 points per game this season
  3. Alabama is averaging 38.0 points per game this season
  4. Alabama is 3-1 ATS this season

Our Alabama Crimson Tide vs Vanderbilt Commodores Prediction

At the start of the season, seeing a ranked game between Vanderbilt and Alabama seemed very unlikely, but that is exactly what we are getting in this matchup. The Commodores are having a dream start to their season, especially offensively, as they are averaging 55 points per game. 

As for Alabama, they stumbled in their season opener, but have since proven they can still be a team to beat. That being said, Vanderbilt quarterback Diego Pavia is putting up Heisman-like numbers, and now has his chance to beat Alabama for the second straight season.

This game is in Alabama, so a Crimson Tide loss seems very unlikely. However, Vanderbilt has played well enough this season to believe they can keep this game close. For that reason, our Vanderbilt Commodores vs Alabama Crimson Tide prediction is: Vanderbilt Commodores +10.5.

Prediction:

 

Vanderbilt Commodores +10.5

-112
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All tips are fully researched and given in good faith, but profits cannot be guaranteed.

Alabama Crimson Tide vs Vanderbilt Commodores Picks