Notre Dame Fighting Irish vs USC Trojans Prediction & Picks - NCAA

Prediction published on 10/18/25, 4:19 PM  by Matt Lowrimore | Modified on 10/19/25 at 2:10 PM in NCAA Picks

One of the most interesting games on the Saturday Week 8 college football slate will see the 20th-ranked USC Trojans take on the 13th-ranked Notre Dame Fighting Irish. Let’s take a look at the match statistics and predictions for this game between the Trojans and the Fighting Irish.

USC enters this game with a record of 5-1, having most recently beaten the Michigan Wolverines in Week 7 by a score of 31-13. The Trojans’ offense had a total of 489 yards, while its defense allowed 316 yards. Quarterback Jayden Maiava threw for 265 yards, two touchdowns, and one interception, while running back King Miller led the team in rushing with 158 yards and one touchdown.

As for Notre Dame, they enter this game with a record of 4-2, having most recently beaten the NC State Wolfpack in Week 7 by a score of 36-7. The Fighting Irish’s offense had a total of 485 yards, while its defense allowed 233 yards. Quarterback CJ Carr threw for 342 yards, two touchdowns, and one interception, while running back Jeremiyah Love led the team in rushing with 86 yards and two touchdowns.