New York City vs Inter Miami Prediction & Picks - Major League Soccer

Prediction published on 9/24/25, 4:10 PM  by Tyler Doty | Modified on 10/7/25 at 9:28 AM in Major League Soccer Picks

Head to the Big Apple and Yankee Stadium to watch one of two MLS games tonight. On Wednesday night, Inter Miami travels to the Bronx to take on New York City, who are one point ahead in the Eastern Conference. With two games in hand, Javier Mascherano's side can hope to climb the table if they can string together some wins at the end of the regular season. Since suffering heavy defeats against Seattle (3-0) and Charlotte (3-0), the Interistas have bounced back on American soil with six wins out of six. But what would the club chaired by David Beckham do without Lionel Messi? La Pulga has carried his team over the last 180 minutes with three goals and two assists. Still performing at a high level in a minor league, the former Barça player shows that talent can still win games. Will it be enough to break a streak of four away games without a single win?

NYCFC has no reason to fear Messi and co. Admittedly, the squad is made up of former stars, but the Herons have numerous defensive problems. Pascal Janser and his men are perfectly prepared for this match, having won three consecutive league games and, even more impressively, five of their last six. Back at home for the last two games and having recently beaten Charlotte without conceding a single goal (2-0), the Pigeons go into this match with one goal in mind: not to let Inter Miami take their fourth place, which would give them home advantage in the upcoming playoffs.