Stefanos Tsitsipas vs Lorenzo Musetti Prediction & Picks - ATP Vienna

ATP - ATP Vienna

ATP 25 Greece
Stefanos Tsitsipas
10/21/25 11:30
ATP 8 Italy
Lorenzo Musetti

Prediction:

 

Stefanos Tsitsipas +3.5 Games

-150
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 by Lou Aguila in Tennis Picks

Lorenzo Musetti of Italy will tussle with Stefanos Tsitsipas of Greece in the first round of the 2025 Erste Bank Open in Vienna, Austria.

Musetti is -220 against the +195 Tsitsipas, who is going through a tough season but remains a dangerous foe because of his reputation as a former top-10 player.

Current Form:

Musetti will be trying to better his quarterfinal finish at the ATP Brussels and establish a potent form in the European indoor season. The Italian defeated Yannick Hanfmann 7-6, 7-5 in the second round but lost to the big-serving Giovanni Mpetshi Perricard 4-6, 6-7 in the quarterfinal round. Musetti is 34-40 in indoor matches in his career.

Tsitsipas is coming off a brief but lucrative stint at the Six Kings Slam, where he pocketed at least $1.5 million despite losing to Jannik Sinner 2-6, 3-6. Again, Tsitsipas is not having a competitive season on the ATP Tour this year. He has now dropped to world’s No.25 after spending the last several years in the top 10 of the world rankings. Injuries have also prevented Tsitsipas from getting solid results in big tournaments in 2025. At the Shanghai Masters, the Greek had to withdraw hours before his match with Nuno Borges because of an injury.

Stefanos Tsitsipas vs Lorenzo Musetti Form

Stefanos Tsitsipas and Lorenzo Musetti Latest Matches

Stefanos Tsitsipas Latest matches
W L L W L L
Victories

2/6 (33%)

Defeats

4/6 (67%)

Oct 15, 2025 - Six King Slam

Stefanos Tsitsipas
0 :  2
Jannik Sinner

Aug 28, 2025 - ATP US Open

Stefanos Tsitsipas
2 :  3
Daniel Altmaier

Aug 26, 2025 - ATP US Open

Stefanos Tsitsipas
3 :  1
Alexandre Muller

Aug 19, 2025 - ATP Winston-Salem Open

Stefanos Tsitsipas
0 :  2
Yunchaokete Bu

Aug 11, 2025 - ATP Cincinnati Open

Stefanos Tsitsipas
1 :  2
Benjamin Bonzi

Aug 9, 2025 - ATP Cincinnati Open

Stefanos Tsitsipas
2 :  0
Fabian Marozsan
Lorenzo Musetti Latest matches
L W W L W L
Victories

4/6 (67%)

Defeats

2/6 (33%)

Oct 17, 2025 - Brussels Open

Lorenzo Musetti
0 :  2
Giovanni Mpetshi Perricard

Oct 16, 2025 - Brussels Open

Lorenzo Musetti
2 :  0
Yannick Hanfmann

Oct 8, 2025 - ATP Shanghai Masters

Felix Auger Aliassime
2 :  0
Lorenzo Musetti

Oct 6, 2025 - ATP Shanghai Masters

Luciano Darderi
0 :  2
Lorenzo Musetti

Oct 4, 2025 - ATP Shanghai Masters

Francisco Comesana
0 :  2
Lorenzo Musetti

Sep 29, 2025 - ATP Beijing Open

Learner Tien
abort
Lorenzo Musetti

Stefanos Tsitsipas against Lorenzo Musetti : Head to Head (H2H)

Stefanos Tsitsipas

67 %

Lorenzo Musetti

33 %

Apr 29, 2025 - ATP Mutua Madrid Open

Stefanos Tsitsipas
0 :  2
Lorenzo Musetti

Apr 11, 2025 - ATP Monte Carlo Masters

Lorenzo Musetti
2 :  1
Stefanos Tsitsipas

May 16, 2023 - ATP Italian Open

Stefanos Tsitsipas
2 :  0
Lorenzo Musetti

Apr 22, 2023 - ATP Barcelona

Lorenzo Musetti
1 :  2
Stefanos Tsitsipas

May 24, 2022 - ATP French Open

Lorenzo Musetti
2 :  3
Stefanos Tsitsipas

May 22, 2021 - ATP Lyon Open

Lorenzo Musetti
1 :  2
Stefanos Tsitsipas
Compare Stefanos Tsitsipas and Lorenzo Musetti with our comparison tool.

Stefanos Tsitsipas - Lorenzo Musetti Key Points

  1. Stefanos Tsitsipas is 22-18 in 2025.
  2. Stefanos Tsitsipas has a 64.5 percent win rate in indoor matches.
  3. Lorenzo Musetti reached the quarterfinals of the 2025 ATP Brussels.
  4. Lorenzo Musetti has a 34-40 record in indoor matches.

Our Stefanos Tsitsipas vs Lorenzo Musetti Prediction

Fearless Forecast: Believe it or not, but I like Stefanos Tsitsipas’ chance in this match against Lorenzo Musetti. The Italian isn’t known to be a force in indoor matches. He’s only 34-40 in indoor matches throughout his career and seemed to struggle against big-serving players in playing conditions that heavily favor power players. Tsitsipas is not in his best shape. He doesn’t have momentum coming into this tournament, yet I still think he’s a significantly better indoor hard-court player than Musetti. While I can’t go all in and recklessly pick him at +200 moneyline, Tsitsipas still dishes a solid value at -150 to cover +3.5 games.

Our betting prediction for Stefanos Tsitsipas vs. Lorenzo Musetti: Lorenzo Musetti +3.5 Games

Prediction:

 

Stefanos Tsitsipas +3.5 Games

-150
$300+ offered for betting!

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Stefanos Tsitsipas vs Lorenzo Musetti Picks