St. Louis Cardinals vs Tampa Bay Rays Prediction & Picks - MLB

USA - MLB

St. Louis Cardinals
8/24/25 12:10
Tampa Bay Rays

Prediction:

 

OVER 9

-105
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 by Travis Pulver in MLB Picks

The St. Louis Cardinals will face off with the Tampa Bay Rays in the final game of a weekend series today at George M. Steinbrenner Field in Tampa, FL. First pitch for this interleague battle is scheduled for 12:10 p.m. EST.

St. Louis got what it needed in the first game on Friday with five runs in the second inning to take a 5-1 lead. Tampa Bay tacked on two more in the third and one in the seventh, but couldn’t close the gap, losing 7-4. They made up for the loss with a 10-6 win last night. The win was highlighted by Carson Williams' first MLB homer, a two-run shot in the seventh that made the score 9-6. Tampa Bay will go with Ryan Pepiot on the mound to start the day. Pepiot has an 8-10 record in 26 starts this season with a 3.95 ERA, 1.19 WHIP, and .230 OBA. He’s gone 5-4 in 13 home starts this season with a 3.46 ERA and .228 OBA.  As for the Cardinals, they’ll send Matthew Liberatore to the mound. Liberatore has gone 6-10 in 23 starts this season with a 4.13 ERA, 1.29 WHIP, and .267 OBA. In 12 road starts, he has gone 2-5 with a 3.73 ERA and .253 OBA.

St. Louis Cardinals vs Tampa Bay Rays Form

Table

Teams % P W L
16
St. Louis Cardinals
St. Louis Cardinals
0.492 132 65 67
18
Tampa Bay Rays
Tampa Bay Rays
0.489 131 64 67

St. Louis Cardinals and Tampa Bay Rays Latest Matches

St. Louis Cardinals
St. Louis Cardinals Latest matches
L W W L W L
Victories

3/6 (50%)

Defeats

3/6 (50%)

Aug 22, 2025 - MLB

St. Louis Cardinals
6 :  10
Tampa Bay Rays

Aug 21, 2025 - MLB

St. Louis Cardinals
7 :  4
Tampa Bay Rays

Aug 20, 2025 - MLB

St. Louis Cardinals
2 :  6
Miami Marlins

Aug 19, 2025 - MLB

St. Louis Cardinals
7 :  4
Miami Marlins

Aug 18, 2025 - MLB

St. Louis Cardinals
8 :  3
Miami Marlins

Aug 17, 2025 - MLB

New York Yankees
8 :  4
St. Louis Cardinals
W L L L L L
Victories

1/6 (17%)

Defeats

5/6 (83%)

Aug 17, 2025 - MLB

New York Yankees
8 :  4
St. Louis Cardinals

Aug 16, 2025 - MLB

New York Yankees
12 :  8
St. Louis Cardinals

Aug 15, 2025 - MLB

New York Yankees
4 :  3
St. Louis Cardinals

Aug 13, 2025 - MLB

Colorado Rockies
6 :  5
St. Louis Cardinals

Aug 12, 2025 - MLB

Colorado Rockies
3 :  0
St. Louis Cardinals

Aug 11, 2025 - MLB

Colorado Rockies
2 :  3
St. Louis Cardinals
L W W L W L
Victories

4/6 (67%)

Defeats

2/6 (33%)

Aug 22, 2025 - MLB

St. Louis Cardinals
6 :  10
Tampa Bay Rays

Aug 21, 2025 - MLB

St. Louis Cardinals
7 :  4
Tampa Bay Rays

Aug 20, 2025 - MLB

St. Louis Cardinals
2 :  6
Miami Marlins

Aug 19, 2025 - MLB

St. Louis Cardinals
7 :  4
Miami Marlins

Aug 18, 2025 - MLB

St. Louis Cardinals
8 :  3
Miami Marlins

Aug 6, 2025 - MLB

St. Louis Cardinals
5 :  3
Los Angeles Dodgers
Tampa Bay Rays
Tampa Bay Rays Latest matches
W L L L L W
Victories

2/6 (33%)

Defeats

4/6 (67%)

Aug 22, 2025 - MLB

St. Louis Cardinals
6 :  10
Tampa Bay Rays

Aug 21, 2025 - MLB

St. Louis Cardinals
7 :  4
Tampa Bay Rays

Aug 20, 2025 - MLB

New York Yankees
6 :  4
Tampa Bay Rays

Aug 19, 2025 - MLB

New York Yankees
13 :  3
Tampa Bay Rays

Aug 17, 2025 - MLB

Tampa Bay Rays
1 :  7
San Francisco Giants

Aug 16, 2025 - MLB

Tampa Bay Rays
2 :  1
San Francisco Giants
W L L L L W
Victories

2/6 (33%)

Defeats

4/6 (67%)

Aug 22, 2025 - MLB

St. Louis Cardinals
6 :  10
Tampa Bay Rays

Aug 21, 2025 - MLB

St. Louis Cardinals
7 :  4
Tampa Bay Rays

Aug 20, 2025 - MLB

New York Yankees
6 :  4
Tampa Bay Rays

Aug 19, 2025 - MLB

New York Yankees
13 :  3
Tampa Bay Rays

Aug 3, 2025 - MLB

Los Angeles Dodgers
3 :  0
Tampa Bay Rays

Aug 2, 2025 - MLB

Los Angeles Dodgers
0 :  4
Tampa Bay Rays
W L W W L W
Victories

4/6 (67%)

Defeats

2/6 (33%)

Aug 17, 2025 - MLB

Tampa Bay Rays
1 :  7
San Francisco Giants

Aug 16, 2025 - MLB

Tampa Bay Rays
2 :  1
San Francisco Giants

Aug 15, 2025 - MLB

Tampa Bay Rays
7 :  6
San Francisco Giants

Aug 13, 2025 - MLB

Tampa Bay Rays
8 :  2
Athletics

Aug 12, 2025 - MLB

Tampa Bay Rays
0 :  6
Athletics

Aug 11, 2025 - MLB

Tampa Bay Rays
7 :  4
Athletics

St. Louis Cardinals against Tampa Bay Rays : Head to Head (H2H)

St. Louis Cardinals

33 %

Tampa Bay Rays

67 %

Aug 22, 2025 - MLB

St. Louis Cardinals
6 :  10
Tampa Bay Rays

Aug 21, 2025 - MLB

St. Louis Cardinals
7 :  4
Tampa Bay Rays

Aug 8, 2023 - MLB

St. Louis Cardinals
2 :  4
Tampa Bay Rays

St. Louis Cardinals - Tampa Bay Rays Key Points

  1. Tampa Bay leads the all-time series vs. St. Louis 14-13.
  2. The Rays have gone 8-8 all-time at home vs. the Cardinals.
  3. Betting Public: 63% of moneyline tickets and 44% of the handle are on the Rays.
  4. Betting Public: 93% of TOTAL tickets and 88% of the handle are on the OVER.

Our St. Louis Cardinals vs Tampa Bay Rays Prediction

Neither pitcher has been too impressive this season, making it challenging to pick a winner between the two. Both teams are hitting well over the last week, with the Cardinals hitting  .248 (34 runs across six games) and the Rays .254 (22 runs across five games). However, they are in a home run-friendly park (181, 2.72 per game); 17 of the 26 home runs Pepiot has given up have come at home. With two home runs Friday and six yesterday, there’s a good chance we’ll see 2-4 today, resulting in a high-scoring game.

Our Cardinals vs. Rays Pick: OVER 9

Prediction:

 

OVER 9

-105
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St. Louis Cardinals vs Tampa Bay Rays Picks