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by Travis Pulver in MLB Picks
The St. Louis Cardinals will try to get back on the right side of the scoreboard today when they face the Pirates at PNC Park in Pittsburgh. Fans can follow the action in this NL Central matchup once the game gets underway at 6:40 p.m. EST.
Andrew Heaney and Chase Shugart pitched a shutout for the Pirates in yesterday’s game, giving up four hits and one walk while striking out eight. Pittsburgh’s lineup got to Errick Fedde early with a run in the bottom of the first courtesy of a Spencer Horowitz home run, but chased Fedde after taking on another six runs in the bottom of the fifth. Pittsburgh will try to keep the good times rolling and win their fifth consecutive game with Paul Skenes taking the mound to start the day. Skenes is only 4-7, but has a 2.12 ERA and a .91 WHIP. He has a 2.56 ERA at home, where he is 1-4 in seven starts, and has held teams to .179 OBA. Andre Pallante will get the start for the Cardinals. Pallante is 5-4 with a 4.43 ERA and 1.35 WHIP. He’s 2-2 in eight road starts with a 4.60 ERA.
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St. Louis Cardinals vs Pittsburgh Pirates Form
Table
Teams | % | P | W | L |
---|---|---|---|---|
11
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0.547 | 86 | 47 | 39 |
26
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0.419 | 86 | 36 | 50 |
St. Louis Cardinals and Pittsburgh Pirates Latest Matches

3/6 (50%)
3/6 (50%)
Jun 30, 2025 - MLB
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3/6 (50%)
3/6 (50%)
Jun 26, 2025 - MLB
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5/6 (83%)
1/6 (17%)
Jun 30, 2025 - MLB
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Jun 19, 2025 - MLB

4/6 (67%)
2/6 (33%)
Jun 30, 2025 - MLB
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5/6 (83%)
1/6 (17%)
Jun 30, 2025 - MLB
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2/6 (33%)
4/6 (67%)
Jun 25, 2025 - MLB
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Jun 17, 2025 - MLB
St. Louis Cardinals against Pittsburgh Pirates : Head to Head (H2H)
67 %
33 %
Jun 30, 2025 - MLB
May 7, 2025 - MLB
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St. Louis Cardinals - Pittsburgh Pirates Key Points
- Pirates lead all-time series with Cardinals 1277-1227-24.
- Pallante is 1-1 with a 2.65 ERA and 22 strikeouts vs. the Pirates.
- Skenes is 0-4 against the Cardinals with a 2.76 ERA and 36 strikeouts.
- Betting Public: 64% of moneyline tickets and 60% of the handle are on the Pirates.
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Our St. Louis Cardinals vs Pittsburgh Pirates Prediction
Normally, I’d lean towards the UNDER for a game Skenes starts since he’ll keep the other team from scoring much, and the Pirates' lineup has not generated much run support for him. But the Pirates are actually on a winning streak right now, so I’ve got to believe Pittsburgh can get Skenes his first win over the Cardinals.
Our Cardinals vs. Pirates Pick: Pittsburgh ML
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All tips are fully researched and given in good faith, but profits cannot be guaranteed.

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