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by Travis Pulver in MLB Picks
The St. Louis Cardinals will take on the White Sox in the second game of a three-game series at Rate Field in Chicago, Illinois. Game time is scheduled for 7:40 p.m. EST.
St. Louis got the series off to a strong start with a 12-2 win over the White Sox in Game One yesterday. Matthew Liberatore pitched six solid innings (five hits, two runs), but the stars of the day were second baseman Brenden Donovan (4-5 with two runs scored and an RBI) and Ivan Herrera (2-5 with four RBI. The Cards recorded a run in six of nine innings. Chicago will hope for a better result with Sean Burke taking the mound to start the day. While Burke has a 4.71 ERA on the season, he has been decidedly better at home, where his ERA is 3.68 across seven outings. It will certainly help if he can get more than the six hits and two runs of support the lineup provided yesterday. St. Louis is scheduled to start Sonny Gray, who has a 3.68 ERA this season but a 5.88 ERA in road games (five). Opponents are hitting .284 against him in road games and .292 at night.
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St. Louis Cardinals vs Chicago White Sox Form
Table
| Teams | % | P | W | L |
|---|---|---|---|---|
|
12
|
0.533 | 75 | 40 | 35 |
|
29
|
0.307 | 75 | 23 | 52 |
St. Louis Cardinals and Chicago White Sox Latest Matches
2/6 (33%)
4/6 (67%)
Jun 17, 2025 - MLB
Jun 15, 2025 - MLB
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Jun 11, 2025 - MLB
2/6 (33%)
4/6 (67%)
Jun 11, 2025 - MLB
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Jun 6, 2025 - MLB
2/6 (33%)
4/6 (67%)
Jun 17, 2025 - MLB
Jun 15, 2025 - MLB
Jun 14, 2025 - MLB
Jun 13, 2025 - MLB
Jun 12, 2025 - MLB
Jun 1, 2025 - MLB
0/6 (0%)
6/6 (100%)
Jun 17, 2025 - MLB
Jun 15, 2025 - MLB
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Jun 11, 2025 - MLB
3/6 (50%)
3/6 (50%)
Jun 17, 2025 - MLB
Jun 8, 2025 - MLB
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Jun 5, 2025 - MLB
Jun 4, 2025 - MLB
1/6 (17%)
5/6 (83%)
Jun 15, 2025 - MLB
Jun 14, 2025 - MLB
Jun 13, 2025 - MLB
Jun 12, 2025 - MLB
Jun 11, 2025 - MLB
Jun 10, 2025 - MLB
St. Louis Cardinals against Chicago White Sox : Head to Head (H2H)
60 %
40 %
Jun 17, 2025 - MLB
May 5, 2024 - MLB
May 3, 2024 - MLB
Aug 16, 2020 - MLB
Aug 15, 2020 - MLB
St. Louis Cardinals - Chicago White Sox Key Points
- The Cardinals lead the all-time series vs. the White Sox, 24-18; Chicago is 11-12 in home games.
- St. Louis has won seven of their last eight against teams with losing records.
- Chicago has lost their last 11 games vs. NL Central teams following a loss.
- Betting Public: Bettors are getting behind the Cardinals with 79% of moneyline tickets and 85% of the handle on St. Louis.
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Our St. Louis Cardinals vs Chicago White Sox Prediction
Neither of these teams has performed well this season. Gray’s road struggles have me concerned for the Cardinals, but the lack of support from the lineup has me concerned about taking the White Sox. Bottom line—St. Louis is the better team between the two, and they should win this game, but the teams that should win don’t always do so. That being said, I’ve still got to go with the Cardinals here.
Our St. Louis vs. Chicago Pick: Cardinals ML
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