Duke vs St. Johns Red Storm Prediction & Picks - NCAA Basketball

USA - NCAA Basketball

Duke
3/27/26 19:10
St. Johns Red Storm

Prediction:

 

St. John's Red Storm +6.5

-108
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 by Matt Lowrimore | in NCAA Basketball Picks

The first Sweet 16 game scheduled for Friday will see the #5-seeded St. John’s Red Storm (30-6) take on the #1-seeded Duke Blue Devils (34-2) in the East Region. Let’s take a look at the match statistics and predictions for this game between the Red Storm and the Blue Devils.

St. John’s needed a layup as time expired to beat the Kansas Jayhawks in the Round of 32. Despite that, the Red Storm are easily the hottest team in the tournament right now, having gone 7-0 in March and winning 21 of their last 22 games. Also in March, St. John’s is 5-2 ATS, which includes 1-1 ATS in the tournament so far.

Duke emphatically bounced back from their scare in the first round against Sienna to comfortably beat the TCU Horned Frogs in the Round of 32 this past weekend. With the win, the Blue Devils are a perfect 7-0 in March. That being said, Duke has been inconsistent against the spread recently, covering in four of their seven games in March.

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Duke vs St. Johns Red Storm Form

Duke and St. Johns Red Storm Latest Matches

Duke
Duke Latest matches
W W W L W W
Victories

5/6 (83%)

Defeats

1/6 (17%)

Mar 21, 2026 - NCAA Basketball

Duke
81 :  58
TCU

Mar 19, 2026 - NCAA Basketball

Duke
71 :  65
Siena Saints

Apr 5, 2025 - NCAA Basketball

Duke
67 :  70
Houston

Mar 27, 2025 - NCAA Basketball

Duke
100 :  93
Arizona

Mar 23, 2025 - NCAA Basketball

Duke
89 :  66
Baylor

Mar 21, 2025 - NCAA Basketball

Duke
93 :  49
Mount St. Marys Mountaineers
W W W L W W
Victories

5/6 (83%)

Defeats

1/6 (17%)

Mar 21, 2026 - NCAA Basketball

Duke
81 :  58
TCU

Mar 19, 2026 - NCAA Basketball

Duke
71 :  65
Siena Saints

Apr 5, 2025 - NCAA Basketball

Duke
67 :  70
Houston

Mar 27, 2025 - NCAA Basketball

Duke
100 :  93
Arizona

Mar 23, 2025 - NCAA Basketball

Duke
89 :  66
Baylor

Mar 21, 2025 - NCAA Basketball

Duke
93 :  49
Mount St. Marys Mountaineers
W
Victories

1/1 (100%)

Defeats

0/1 (0%)

Mar 29, 2024 - NCAA Basketball

Houston
51 :  54
Duke
St. Johns Red Storm
St. Johns Red Storm Latest matches
L W W
Victories

2/3 (67%)

Defeats

1/3 (33%)

Mar 22, 2026 - NCAA Basketball

KU
65 :  67
St. Johns Red Storm

Mar 20, 2026 - NCAA Basketball

St. Johns Red Storm
79 :  53
Northern Iowa Panthers

Mar 22, 2025 - NCAA Basketball

St. Johns Red Storm
66 :  75
Arkansas Razorbacks
L W
Victories

1/2 (50%)

Defeats

1/2 (50%)

Mar 20, 2026 - NCAA Basketball

St. Johns Red Storm
79 :  53
Northern Iowa Panthers

Mar 22, 2025 - NCAA Basketball

St. Johns Red Storm
66 :  75
Arkansas Razorbacks
W
Victories

1/1 (100%)

Defeats

0/1 (0%)

Mar 22, 2026 - NCAA Basketball

KU
65 :  67
St. Johns Red Storm
Duke vs St. Johns Red Storm Picks

Duke - St. Johns Red Storm Key Points

  1. St. John’s is 21-1 SU in their last 22 games
  2. St. John’s is 5-2 ATS in March
  3. Duke is 4-3 ATS in March
  4. Duke is 7-0 SU in March
Up to $150 to bet on Duke - St. Johns Red Storm! 

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Our Duke vs St. Johns Red Storm Prediction

Duke is the clear favorite in this game; however, St. John’s looks to be the best betting option. The Red Storm may have barely survived against the Jayhawks, but it is too hard to ignore their stretch of 21 wins in their last 22 games. 

Additionally, St. John’s is 4-1 ATS over their last five games, while Duke is 2-3 ATS over the same stretch. Therefore, given that the Red Storm has consistently covered the spread recently, while Duke has overall been inconsistent with this recently, our St. John’s Red Storm vs Duke Blue Devils prediction is: St. John’s Red Storm +6.5.

Prediction:

 

St. John's Red Storm +6.5

-108
$150 offered for betting!

All tips are fully researched and given in good faith, but profits cannot be guaranteed.