Seattle Seahawks vs San Francisco 49ers Prediction & Picks - NFL
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by Matt Lowrimore in NFL Picks
Week 18 of the NFL will feature two Saturday games, one of which will see the San Francisco 49ers take on the Seattle Seahawks. Let’s take a look at the match statistics and predictions for this game between the 49ers and the Seahawks.
Seattle enters this game with a record of 13-3, having most recently beaten the Carolina Panthers in Week 17 by a score of 27-10. The Seahawks’ offense had a total of 288 yards, while its defense allowed 139 yards. Quarterback Sam Darnold threw for 147 yards, one touchdown, and one interception, while running back Zach Charbonnet led the team in rushing with 110 yards and two touchdowns.
As for San Francisco, they enter this game with a record of 12-4, having most recently beaten the Chicago Bears in Week 17 by a score of 42-38. The 49ers’ offense had a total of 496 yards, while its defense allowed 440 yards. Quarterback Brock Purdy threw for 303 yards, three touchdowns, and one interception, while running back Christian McCaffrey led the team in rushing with 140 yards and one touchdown.
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Seattle Seahawks vs San Francisco 49ers Form
Table
| Teams | % | P | W | D | L |
|---|---|---|---|---|---|
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1
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0.813 | 16 | 13 | 0 | 3 |
|
5
|
0.75 | 16 | 12 | 0 | 4 |
Seattle Seahawks and San Francisco 49ers Latest Matches
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Seattle Seahawks against San Francisco 49ers : Head to Head (H2H)
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Seattle Seahawks - San Francisco 49ers Key Points
- Seattle is 7-1 SU on the road
- Seattle is 6-0 SU in their last 6 games
- San Francisco is 5-2 SU at home
- San Francisco is 6-0 SU in their last 6 games
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Our Seattle Seahawks vs San Francisco 49ers Prediction
The Seahawks are the small road favorites; however, the 49ers look to be the best betting option. This game has a lot at stake as the winner will also win the NFC West division and earn the number one seed in the NFC playoffs.
The 49ers have already beaten the Seahawks this season, albeit all the way back in Week 1. Both teams are also on a tear, having won their last six games in a row. That being said, the 49ers seemingly have the X-factor in this matchup with Christian McCaffrey. He has been the focal point for this offense and has proven he can do just about everything.
Even though the Seahawks have only lost one road game this season, our San Francisco 49ers vs Seattle Seahawks prediction is: San Francisco 49ers +1.5.Claim $200 for your Seattle Seahawks vs San Francisco 49ers wager!

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All tips are fully researched and given in good faith, but profits cannot be guaranteed.