Seattle Seahawks vs Carolina Panthers Prediction & Picks - NFL

USA - NFL

Seattle Seahawks
12/28/25 13:00
Carolina Panthers

Prediction:

 

Over 42.5.

-112
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 by Carlos Zabala in NFL Picks

The Panthers are coming off their most crucial win of the season, a 23-20 victory over the Buccaneers at Bank of America Stadium in Week 16, which knocked them out of first place in the division. This week, the Panthers will face the Bucs again, this time in Tampa, in a high-stakes matchup. But first, they face the challenge of hosting the conference-leading 12-3 Seahawks. Betting sites favor Seattle by 7 points in pregame odds.

The Panthers capitalized on a Lathan Ransom interception of Baker Mayfield that ended Tampa's final drive. In the win, Ryce Young threw two touchdown passes, but far from getting too carried away, the Carolina quarterback emphasized that the next game against Seattle is the most important of all.

The Seahawks, already in the playoffs, will look to secure their sixth consecutive victory in Charlotte. So far, the Titans, Vikings, Colts, and Rams have been their victims. Their latest victory was their most valuable, a 38-37 win over Los Angeles. Rashid Shaheed returned a punt 58 yards for a touchdown. This ignited the Seahawks' comeback, as they scored 16 points in the fourth quarter and won overtime 8-7.

Seattle Seahawks vs Carolina Panthers Form

Table

Teams % P W D L
1
Seattle Seahawks
Seattle Seahawks
0.813 16 13 0 3
14
Carolina Panthers
Carolina Panthers
0.5 16 8 0 8

Seattle Seahawks and Carolina Panthers Latest Matches

Seattle Seahawks
Seattle Seahawks Latest matches
L W W W W W
Victories

5/6 (83%)

Draw

0/6 (0%)

Defeats

1/6 (17%)

Dec 18, 2025 - NFL

Los Angeles Rams
37 :  38
Seattle Seahawks

Dec 14, 2025 - NFL

Indianapolis Colts
16 :  18
Seattle Seahawks

Dec 7, 2025 - NFL

Seattle Seahawks
37 :  9
Atlanta Falcons

Nov 30, 2025 - NFL

Minnesota Vikings
0 :  26
Seattle Seahawks

Nov 23, 2025 - NFL

Seattle Seahawks
30 :  24
Tennessee Titans

Nov 16, 2025 - NFL

Seattle Seahawks
19 :  21
Los Angeles Rams
L W W W W W
Victories

5/6 (83%)

Draw

0/6 (0%)

Defeats

1/6 (17%)

Dec 18, 2025 - NFL

Los Angeles Rams
37 :  38
Seattle Seahawks

Dec 14, 2025 - NFL

Indianapolis Colts
16 :  18
Seattle Seahawks

Nov 30, 2025 - NFL

Minnesota Vikings
0 :  26
Seattle Seahawks

Nov 9, 2025 - NFL

Arizona Cardinals
22 :  44
Seattle Seahawks

Oct 20, 2025 - NFL

Houston Texans
19 :  27
Seattle Seahawks

Oct 5, 2025 - NFL

Tampa Bay Buccaneers
38 :  35
Seattle Seahawks
W W W L W W
Victories

5/6 (83%)

Draw

0/6 (0%)

Defeats

1/6 (17%)

Dec 7, 2025 - NFL

Seattle Seahawks
37 :  9
Atlanta Falcons

Nov 23, 2025 - NFL

Seattle Seahawks
30 :  24
Tennessee Titans

Nov 16, 2025 - NFL

Seattle Seahawks
19 :  21
Los Angeles Rams

Nov 2, 2025 - NFL

Seattle Seahawks
38 :  14
Washington Commanders

Oct 12, 2025 - NFL

Seattle Seahawks
20 :  12
Jacksonville Jaguars

Sep 25, 2025 - NFL

Seattle Seahawks
23 :  20
Arizona Cardinals
Carolina Panthers
Carolina Panthers Latest matches
L W L W L W
Victories

3/6 (50%)

Draw

0/6 (0%)

Defeats

3/6 (50%)

Dec 21, 2025 - NFL

Tampa Bay Buccaneers
20 :  23
Carolina Panthers

Dec 14, 2025 - NFL

Carolina Panthers
17 :  20
New Orleans Saints

Nov 30, 2025 - NFL

Los Angeles Rams
28 :  31
Carolina Panthers

Nov 24, 2025 - NFL

Carolina Panthers
9 :  20
San Francisco 49ers

Nov 16, 2025 - NFL

Carolina Panthers
30 :  27
Atlanta Falcons

Nov 9, 2025 - NFL

New Orleans Saints
17 :  7
Carolina Panthers
W W L L W W
Victories

4/6 (67%)

Draw

0/6 (0%)

Defeats

2/6 (33%)

Dec 21, 2025 - NFL

Tampa Bay Buccaneers
20 :  23
Carolina Panthers

Nov 30, 2025 - NFL

Los Angeles Rams
28 :  31
Carolina Panthers

Nov 9, 2025 - NFL

New Orleans Saints
17 :  7
Carolina Panthers

Oct 26, 2025 - NFL

Buffalo Bills
40 :  9
Carolina Panthers

Oct 12, 2025 - NFL

Dallas Cowboys
27 :  30
Carolina Panthers

Oct 5, 2025 - NFL

Miami Dolphins
24 :  27
Carolina Panthers
L W W W L L
Victories

3/6 (50%)

Draw

0/6 (0%)

Defeats

3/6 (50%)

Dec 14, 2025 - NFL

Carolina Panthers
17 :  20
New Orleans Saints

Nov 24, 2025 - NFL

Carolina Panthers
9 :  20
San Francisco 49ers

Nov 16, 2025 - NFL

Carolina Panthers
30 :  27
Atlanta Falcons

Nov 2, 2025 - NFL

Carolina Panthers
16 :  13
Green Bay Packers

Oct 19, 2025 - NFL

Carolina Panthers
13 :  6
New York Jets

Sep 28, 2025 - NFL

Carolina Panthers
13 :  42
New England Patriots

Seattle Seahawks - Carolina Panthers Key Points

  1. The Seahawks' O/U record this season is 9-6
  2. Bryce Young of the Panthers has thrown for 21 touchdowns and 9 interceptions this season
  3. The Seahawks are averaging 364.7 yards per game, eighth best in the NFL.
  4. The Seahawks have won 9 of their last 10 games and covered the spread in 7 of them

Our Seattle Seahawks vs Carolina Panthers Prediction

Although the Seahawks, led by Sam Darnold, have already clinched a playoff berth, they still need one more win to secure the number one seed in the conference.

There are several interconnected stories between the two teams; Darnold has delivered as Seattle's quarterback three years after the Panthers released him. Meanwhile, Dave Canales, the Panthers' current head coach, was a protégé of Pete Carroll when he worked for Seattle.

Our prediction for Panthers vs Seahawks is: Over 42.5.

Prediction:

 

Over 42.5.

-112
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All tips are fully researched and given in good faith, but profits cannot be guaranteed.

Seattle Seahawks vs Carolina Panthers Picks