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by Travis Pulver in MLB Picks
The Astros will host the Seattle Mariners in Game Two of a three-game weekend series at Daikin Park in Houston, TX, today. First Pitch for this AL West battle for control of the division pennant is scheduled for 7:10 p.m. EST. The game will be broadcast on MLB TV.
After Friday’s 4-0 win over the Astros, the Mariners slid into first in the AL West. Houston has held the top spot in the division for most of the season but has played inconsistently down the stretch (6-4 in their last ten) while the Mariners have been winning games (9-1 in their last ten). But Houston has the easier road in the final week with three vs. the A’s in Sacramento and three vs. the Angels in LA. The Mariners have a series vs. the Rockies and the Dodgers. The pitching matchup favors the Astros today with Framber Valdez (12-10, 3.59 ERA) taking the mound against George Kirby (9-7, 4.46 ERA). Valdez has struggled this month, posting a 7.88 ERA through three games, but has been solid at home this season (6-3 in 14 starts with a 2.21 ERA and .217 OBA. Kirby has had some issues on the road, posting a 4-4 record in ten starts with a 5.74 ERA and .285 OBA.
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Seattle Mariners vs Houston Astros Form
Table
Teams | % | P | W | L |
---|---|---|---|---|
7
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0.558 | 156 | 87 | 69 |
11
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0.538 | 156 | 84 | 72 |
Seattle Mariners and Houston Astros Latest Matches

5/6 (83%)
1/6 (17%)
Sep 19, 2025 - MLB
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6/6 (100%)
0/6 (0%)
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5/6 (83%)
1/6 (17%)
Sep 19, 2025 - MLB
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4/6 (67%)
2/6 (33%)
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4/6 (67%)
2/6 (33%)
Sep 19, 2025 - MLB
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3/6 (50%)
3/6 (50%)
Sep 14, 2025 - MLB
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Seattle Mariners against Houston Astros : Head to Head (H2H)
67 %
33 %
Sep 19, 2025 - MLB
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Seattle Mariners - Houston Astros Key Points
- Houston leads the all-time series vs. Seattle 135-95 but trails the season series 5-6.
- Valdez has gone 6-5 in 17 starts at night with two complete games, a 2.82 ERA, and .229 OBA.
- Kirby has gone 5-7 in 16 night starts with a 4.75 ERA and .277 OBA.
- Betting Public: 89% of moneyline tickets are on the Mariners, but 71% of run line tickets are on Houston.
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Our Seattle Mariners vs Houston Astros Prediction
Both teams certainly need this win. I’d like to give Houston an edge since Valdez has been the better pitcher over the course of the entire season. But his recent struggles can’t be ignored. With only 11% of moneyline tickets on the Astros but 42% of the handle, that tells me the sharps are backing Houston. I can see this game going either way, so I’m going to bet with the sharps.
Our Mariners vs. Astros Pick: Houston ML
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