Seattle Mariners vs Chicago Cubs Prediction & Picks - MLB

USA - MLB

Seattle Mariners
6/21/25 14:20
Chicago Cubs

Prediction:

 

UNDER 12.5

-115
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 by Travis Pulver in MLB Picks

The Cubs will look to get back on the right side of the scoreboard today when they face the Seattle Mariners in the second game of their weekend series. Seattle won Friday’s game 9-4 after getting two home runs from Cal Raleigh and Mitch Garver. Fans can follow the action today once the game gets underway at Kyle Field at 2:20 p.m. EST.

Chicago is having a solid year, going 45-30 to date (24-14 at home, 21-16 on the road). They are second in runs scored with 401 (Dodgers, 426), but their eighth when it comes to scoring at home (185). The pitching staff ranks tenth with a 3.69 ERA (starters—3.93, relievers—3.38). They’ll give Cade Horton the ball to start the day. Horton has gone 3-1 in seven starts with a 3.47 ERA and 1.21 WHIP. Seattle has been competitive in the AL West at 38-36, going 20-19 at home and 18-17 on the road. For the season, they are hitting .243, but they are actually hitting better on the road (.265, second best behind the Cubs). They’ll be giving the ball to Emerson Hancock to start the day. Hancock is 3-2 on the year with a 4.48 ERA but has allowed three runs across three starts in June (1.53 ERA).

Seattle Mariners vs Chicago Cubs Form

Table

Teams % P W L
4
Chicago Cubs
Chicago Cubs
0.597 77 46 31
14
Seattle Mariners
Seattle Mariners
0.513 76 39 37

Seattle Mariners and Chicago Cubs Latest Matches

Seattle Mariners
Seattle Mariners Latest matches
W W L L W W
Victories

4/6 (67%)

Defeats

2/6 (33%)

Jun 20, 2025 - MLB

Seattle Mariners
9 :  4
Chicago Cubs

Jun 18, 2025 - MLB

Boston Red Sox
3 :  1
Seattle Mariners

Jun 17, 2025 - MLB

Boston Red Sox
0 :  8
Seattle Mariners

Jun 16, 2025 - MLB

Boston Red Sox
2 :  0
Seattle Mariners

Jun 15, 2025 - MLB

Cleveland Guardians
0 :  6
Seattle Mariners

Jun 14, 2025 - MLB

Cleveland Guardians
3 :  4
Seattle Mariners
W W W L W L
Victories

4/6 (67%)

Defeats

2/6 (33%)

Jun 18, 2025 - MLB

Boston Red Sox
3 :  1
Seattle Mariners

Jun 17, 2025 - MLB

Boston Red Sox
0 :  8
Seattle Mariners

Jun 16, 2025 - MLB

Boston Red Sox
2 :  0
Seattle Mariners

Jun 15, 2025 - MLB

Cleveland Guardians
0 :  6
Seattle Mariners

Jun 14, 2025 - MLB

Cleveland Guardians
3 :  4
Seattle Mariners

Jun 13, 2025 - MLB

Cleveland Guardians
2 :  7
Seattle Mariners
L W L L L W
Victories

2/6 (33%)

Defeats

4/6 (67%)

Jun 20, 2025 - MLB

Seattle Mariners
9 :  4
Chicago Cubs

Jun 11, 2025 - MLB

Seattle Mariners
2 :  5
Arizona Diamondbacks

Jun 10, 2025 - MLB

Seattle Mariners
3 :  10
Arizona Diamondbacks

Jun 9, 2025 - MLB

Seattle Mariners
4 :  8
Arizona Diamondbacks

Jun 8, 2025 - MLB

Seattle Mariners
3 :  2
Los Angeles Angels

Jun 7, 2025 - MLB

Seattle Mariners
6 :  8
Los Angeles Angels
Chicago Cubs
Chicago Cubs Latest matches
W W W W L L
Victories

3/6 (50%)

Defeats

3/6 (50%)

Jun 20, 2025 - MLB

Seattle Mariners
9 :  4
Chicago Cubs

Jun 19, 2025 - MLB

Milwaukee Brewers
8 :  7
Chicago Cubs

Jun 17, 2025 - MLB

Milwaukee Brewers
3 :  5
Chicago Cubs

Jun 15, 2025 - MLB

Pittsburgh Pirates
2 :  3
Chicago Cubs

Jun 14, 2025 - MLB

Pittsburgh Pirates
1 :  2
Chicago Cubs

Jun 13, 2025 - MLB

Pittsburgh Pirates
2 :  1
Chicago Cubs
L W W W L L
Victories

3/6 (50%)

Defeats

3/6 (50%)

Jun 20, 2025 - MLB

Seattle Mariners
9 :  4
Chicago Cubs

Jun 19, 2025 - MLB

Milwaukee Brewers
8 :  7
Chicago Cubs

Jun 17, 2025 - MLB

Milwaukee Brewers
3 :  5
Chicago Cubs

Jun 15, 2025 - MLB

Pittsburgh Pirates
2 :  3
Chicago Cubs

Jun 14, 2025 - MLB

Pittsburgh Pirates
1 :  2
Chicago Cubs

Jun 13, 2025 - MLB

Pittsburgh Pirates
2 :  1
Chicago Cubs
L W L L W L
Victories

2/6 (33%)

Defeats

4/6 (67%)

Jun 11, 2025 - MLB

Chicago Cubs
2 :  7
Philadelphia Phillies

Jun 10, 2025 - MLB

Chicago Cubs
8 :  4
Philadelphia Phillies

Jun 9, 2025 - MLB

Chicago Cubs
3 :  4
Philadelphia Phillies

Jun 8, 2025 - MLB

Chicago Cubs
0 :  4
Detroit Tigers

Jun 7, 2025 - MLB

Chicago Cubs
6 :  1
Detroit Tigers

Jun 6, 2025 - MLB

Chicago Cubs
1 :  3
Detroit Tigers

Seattle Mariners against Chicago Cubs : Head to Head (H2H)

Seattle Mariners

33 %

Chicago Cubs

67 %

Jun 20, 2025 - MLB

Seattle Mariners
9 :  4
Chicago Cubs

Mar 8, 2025 - MLB Spring Training

Seattle Mariners
8 :  9
Chicago Cubs

Apr 13, 2024 - MLB

Chicago Cubs
4 :  1
Seattle Mariners

Apr 12, 2024 - MLB

Chicago Cubs
2 :  4
Seattle Mariners

Mar 24, 2021 - MLB Spring Training

Chicago Cubs
6 :  2
Seattle Mariners

Mar 3, 2021 - MLB Spring Training

Seattle Mariners
8 :  8
Chicago Cubs

Seattle Mariners - Chicago Cubs Key Points

  1. In the limited history between these two teams, the Cubs lead the all-time series 17-9.
  2. Seattle has lost their last four road games after a win.
  3. Chicago has followed 11 of their last 13 losses with a win.
  4. Betting Public: The public is split regarding the total, with 50% of total tickets on the UNDER and 50% on the OVER. However, 60% of the handle is on the OVER, and 40% is on the UNDER.

Our Seattle Mariners vs Chicago Cubs Prediction

This game has the makings of a pitcher’s duel. Neither pitcher gave up a run in their previous outing, and neither offense has been really explosive. The nine runs Seattle had last night matched their total from the previous three games combined. Both teams have struggled at the plate over the last week (Chicago-- .223 and Seattle-- .228). Temper expectations for both teams today with how they’re hitting and with good pitchers on the mound.

Our Seattle vs. Chicago Pick: UNDER 12.5 

Prediction:

 

UNDER 12.5

-115
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Seattle Mariners vs Chicago Cubs Picks