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by Carlos Zabala in MLB Picks
It's official: the Twins put their poor start to the season behind them and quickly leveled their record, now at 20-20, with tremendous solid play at Target Field in Minneapolis, where they have a 14-6 record. After beating the Giants 3-1 in Game 1, Ryan led Game 2, looking at his best again in 2025, and led the Twins to a 2-1 victory in Game 2. With this, the Twins have won seven straight and will seek a sweep against San Francisco before traveling to Baltimore and Milwaukee.
Many bettors believe they will complete the sweep against the 24-16 Giants. Mainly because the pitching duel seems conducive, the Twins will be opting for Venezuelan Pablo Lopez, who has a 2.18 ERA this season and is coming off an 11-strikeout game in his last start. Roupp will be the Giants' starter; he hasn't pitched six innings in any of his last three starts.
The Twins won Game 2 thanks to a Larnach RBI home run in the third inning. That game was a pitching duel between Webb and Ryan, with only nine hits between the two teams.
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San Francisco Giants vs Minnesota Twins Form
Table
Teams | % | P | W | L |
---|---|---|---|---|
6
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0.585 | 41 | 24 | 17 |
15
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0.512 | 41 | 21 | 20 |
San Francisco Giants and Minnesota Twins Latest Matches

3/6 (50%)
3/6 (50%)
May 10, 2025 - MLB
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May 5, 2025 - MLB
May 4, 2025 - MLB
5/6 (83%)
1/6 (17%)
May 4, 2025 - MLB
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May 1, 2025 - MLB
Apr 27, 2025 - MLB
Apr 26, 2025 - MLB
2/6 (33%)
4/6 (67%)
May 10, 2025 - MLB
May 9, 2025 - MLB
May 7, 2025 - MLB
May 6, 2025 - MLB
May 5, 2025 - MLB
Apr 30, 2025 - MLB

6/6 (100%)
0/6 (0%)
May 10, 2025 - MLB
May 9, 2025 - MLB
May 8, 2025 - MLB
May 7, 2025 - MLB
May 6, 2025 - MLB
May 4, 2025 - MLB
6/6 (100%)
0/6 (0%)
May 10, 2025 - MLB
May 9, 2025 - MLB
May 8, 2025 - MLB
May 7, 2025 - MLB
May 6, 2025 - MLB
Apr 27, 2025 - MLB
2/6 (33%)
4/6 (67%)
May 4, 2025 - MLB
May 3, 2025 - MLB
May 2, 2025 - MLB
May 1, 2025 - MLB
Apr 30, 2025 - MLB
Apr 29, 2025 - MLB
San Francisco Giants against Minnesota Twins : Head to Head (H2H)
40 %
60 %
May 10, 2025 - MLB
May 9, 2025 - MLB
Jul 14, 2024 - MLB
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Jul 12, 2024 - MLB
San Francisco Giants - Minnesota Twins Key Points
- Twins closer Duran recorded his seventh save in Game 2
- The Twins struck out 12 times in Saturday's win
- Giants' 10-1 record in Game 3 of the series
- Lopez hasn't issued more than 2 walks in any of his last 5 outings
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Our San Francisco Giants vs Minnesota Twins Prediction
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