San Francisco Giants vs Milwaukee Brewers Prediction & Picks - MLB

USA - MLB

San Francisco Giants
8/23/25 19:10
Milwaukee Brewers

Prediction:

 

Milwaukee ML

-140
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 by Travis Pulver in MLB Picks

The Milwaukee Brewers will host the San Francisco Giants in Game Two of a three-game weekend series today at American Family Field. First Pitch for this NL contest is scheduled for 7:10 p.m. EST.

These are two teams on the complete opposite ends of the competitive spectrum. Since the All-Star break, the Brewers have been the hottest team in baseball, posting a 25-8 record with a +85-run differential. San Francisco, on the other hand, has had the worst record since the break at 9-23 with a -34-run differential. Milwaukee will turn to Freddy Peralta on the mound today. Peralta is 15-5 in 26 starts with a 2.78 ERA, 1.10 WHIP, and .199 OBA. He’s gone 8-1 at home in 13 starts with a 1.95 ERA and .203 OBA. However, he did take a loss on April 23 when the Brewers faced the Giants in San Francisco (5 innings, five hits, three earned runs; final score, 4-2). The Giants will turn to Logan Webb. He’s gone 11-9 in 26 starts with a 3.19 ERA. 1.11 WHIP, and .261 OBA. Webb has gone 5-6 on the road in 12 starts with a 3.70 ERA and .269 OBA.

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San Francisco Giants vs Milwaukee Brewers Form

Table

Teams % P W L
1
Milwaukee Brewers
Milwaukee Brewers
0.628 129 81 48
21
San Francisco Giants
San Francisco Giants
0.473 129 61 68

San Francisco Giants and Milwaukee Brewers Latest Matches

San Francisco Giants
San Francisco Giants Latest matches
W W L L L L
Victories

2/6 (33%)

Defeats

4/6 (67%)

Aug 22, 2025 - MLB

San Francisco Giants
4 :  5
Milwaukee Brewers

Aug 21, 2025 - MLB

San Francisco Giants
4 :  8
San Diego Padres

Aug 20, 2025 - MLB

San Francisco Giants
1 :  8
San Diego Padres

Aug 19, 2025 - MLB

San Francisco Giants
1 :  5
San Diego Padres

Aug 18, 2025 - MLB

San Francisco Giants
4 :  3
San Diego Padres

Aug 17, 2025 - MLB

Tampa Bay Rays
1 :  7
San Francisco Giants
L L L L L W
Victories

1/6 (17%)

Defeats

5/6 (83%)

Aug 17, 2025 - MLB

Tampa Bay Rays
1 :  7
San Francisco Giants

Aug 16, 2025 - MLB

Tampa Bay Rays
2 :  1
San Francisco Giants

Aug 15, 2025 - MLB

Tampa Bay Rays
7 :  6
San Francisco Giants

Aug 13, 2025 - MLB

San Diego Padres
11 :  1
San Francisco Giants

Aug 12, 2025 - MLB

San Diego Padres
5 :  1
San Francisco Giants

Aug 11, 2025 - MLB

San Diego Padres
4 :  1
San Francisco Giants
W W L L L L
Victories

2/6 (33%)

Defeats

4/6 (67%)

Aug 22, 2025 - MLB

San Francisco Giants
4 :  5
Milwaukee Brewers

Aug 21, 2025 - MLB

San Francisco Giants
4 :  8
San Diego Padres

Aug 20, 2025 - MLB

San Francisco Giants
1 :  8
San Diego Padres

Aug 19, 2025 - MLB

San Francisco Giants
1 :  5
San Diego Padres

Aug 18, 2025 - MLB

San Francisco Giants
4 :  3
San Diego Padres

Aug 6, 2025 - MLB

San Francisco Giants
4 :  2
Pittsburgh Pirates
Milwaukee Brewers
Milwaukee Brewers Latest matches
W L L L W W
Victories

3/6 (50%)

Defeats

3/6 (50%)

Aug 22, 2025 - MLB

San Francisco Giants
4 :  5
Milwaukee Brewers

Aug 21, 2025 - MLB

Milwaukee Brewers
4 :  1
Chicago Cubs

Aug 20, 2025 - MLB

Milwaukee Brewers
3 :  4
Chicago Cubs

Aug 19, 2025 - MLB

Milwaukee Brewers
1 :  4
Chicago Cubs

Aug 19, 2025 - MLB

Milwaukee Brewers
4 :  6
Chicago Cubs

Aug 18, 2025 - MLB

Milwaukee Brewers
7 :  0
Chicago Cubs
W W W W W W
Victories

6/6 (100%)

Defeats

0/6 (0%)

Aug 22, 2025 - MLB

San Francisco Giants
4 :  5
Milwaukee Brewers

Aug 13, 2025 - MLB

Pittsburgh Pirates
5 :  12
Milwaukee Brewers

Aug 12, 2025 - MLB

Pittsburgh Pirates
0 :  14
Milwaukee Brewers

Aug 11, 2025 - MLB

Pittsburgh Pirates
1 :  7
Milwaukee Brewers

Aug 10, 2025 - MLB

New York Mets
6 :  7
Milwaukee Brewers

Aug 9, 2025 - MLB

New York Mets
4 :  7
Milwaukee Brewers
L W L L L W
Victories

2/6 (33%)

Defeats

4/6 (67%)

Aug 21, 2025 - MLB

Milwaukee Brewers
4 :  1
Chicago Cubs

Aug 20, 2025 - MLB

Milwaukee Brewers
3 :  4
Chicago Cubs

Aug 19, 2025 - MLB

Milwaukee Brewers
1 :  4
Chicago Cubs

Aug 19, 2025 - MLB

Milwaukee Brewers
4 :  6
Chicago Cubs

Aug 18, 2025 - MLB

Milwaukee Brewers
7 :  0
Chicago Cubs

Aug 17, 2025 - MLB

Milwaukee Brewers
2 :  3
Cincinnati Reds

San Francisco Giants against Milwaukee Brewers : Head to Head (H2H)

San Francisco Giants

50 %

Milwaukee Brewers

50 %

Aug 22, 2025 - MLB

San Francisco Giants
4 :  5
Milwaukee Brewers

Apr 24, 2025 - MLB

Milwaukee Brewers
5 :  6
San Francisco Giants

Apr 23, 2025 - MLB

Milwaukee Brewers
2 :  4
San Francisco Giants

Apr 22, 2025 - MLB

Milwaukee Brewers
11 :  3
San Francisco Giants

Apr 21, 2025 - MLB

Milwaukee Brewers
2 :  5
San Francisco Giants

Mar 14, 2025 - MLB Spring Training

San Francisco Giants
5 :  11
Milwaukee Brewers

San Francisco Giants - Milwaukee Brewers Key Points

  1. San Francisco leads the all-time series vs. Milwaukee 104-86 and leads the season series 3-2.
  2. In 38 at-bats vs. Peralta, the Giants hit .368 (14 hits, no home runs).
  3. Webb pitched a shutout vs. the Giants and Peralta on April 23 (6 1/3 innings, six hits, six strikeouts, and three walks).
  4. Betting Public: 86% of moneyline tickets and 94% of the handle are on the Giants.
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Our San Francisco Giants vs Milwaukee Brewers Prediction

On the surface, it is easy to think the Brewers should run away with this. They have been playing the best baseball since the break, while the Giants have been the worst. However, the final on Friday was just 5-4, and Webb and the Giants did beat Peralta and the Brewers in April. That being said, neither team is playing like they did back in April. While taking the runline and a higher payout is tempting, the best bet here is the moneyline.

Our Giants vs. Brewers Pick: Milwaukee ML

Prediction:

 

Milwaukee ML

-140
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All tips are fully researched and given in good faith, but profits cannot be guaranteed.

San Francisco Giants vs Milwaukee Brewers Picks
Up to $250 to bet on San Francisco Giants - Milwaukee Brewers! 

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