San Francisco Giants vs Milwaukee Brewers Prediction & Picks - MLB

USA - MLB

San Francisco Giants
8/22/25 20:10
Milwaukee Brewers

Prediction:

 

Brewers -1.5.

+122
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 by Carlos Zabala in MLB Picks

The Brewers saved the final game of a five-game series against the Cubs at Wrigley Field, where they also won Game 1. With this, the Brew Crew became the first MLB team to reach 80 wins.

After breaking the franchise record for the longest winning streak in history, the Brewers are positioned as the third-place favorite to win the 2025 MLB World Series.

In Thursday's game, before returning to American Family Field for a three-game series against the Giants, the Brewers defeated the Cubs 4-1. Imanaga pitched a solid seven innings for the Cubs; still, he was no better than Milwaukee's experienced bullpen and Megill, who recorded his 30th save of the season.

Meanwhile, Verlander once had a poor outing with the Giants; The Padres scored seven earned runs off the veteran in a game the Padres won 8-4, completing the sweep of San Francisco.

San Francisco Giants vs Milwaukee Brewers Form

Table

Teams % P W L
1
Milwaukee Brewers
Milwaukee Brewers
0.625 128 80 48
20
San Francisco Giants
San Francisco Giants
0.477 128 61 67

San Francisco Giants and Milwaukee Brewers Latest Matches

San Francisco Giants
San Francisco Giants Latest matches
L W W L L L
Victories

2/6 (33%)

Defeats

4/6 (67%)

Aug 21, 2025 - MLB

San Francisco Giants
4 :  8
San Diego Padres

Aug 20, 2025 - MLB

San Francisco Giants
1 :  8
San Diego Padres

Aug 19, 2025 - MLB

San Francisco Giants
1 :  5
San Diego Padres

Aug 18, 2025 - MLB

San Francisco Giants
4 :  3
San Diego Padres

Aug 17, 2025 - MLB

Tampa Bay Rays
1 :  7
San Francisco Giants

Aug 16, 2025 - MLB

Tampa Bay Rays
2 :  1
San Francisco Giants
L L L L W L
Victories

1/6 (17%)

Defeats

5/6 (83%)

Aug 17, 2025 - MLB

Tampa Bay Rays
1 :  7
San Francisco Giants

Aug 16, 2025 - MLB

Tampa Bay Rays
2 :  1
San Francisco Giants

Aug 15, 2025 - MLB

Tampa Bay Rays
7 :  6
San Francisco Giants

Aug 13, 2025 - MLB

San Diego Padres
11 :  1
San Francisco Giants

Aug 12, 2025 - MLB

San Diego Padres
5 :  1
San Francisco Giants

Aug 11, 2025 - MLB

San Diego Padres
4 :  1
San Francisco Giants
W W W L L L
Victories

3/6 (50%)

Defeats

3/6 (50%)

Aug 21, 2025 - MLB

San Francisco Giants
4 :  8
San Diego Padres

Aug 20, 2025 - MLB

San Francisco Giants
1 :  8
San Diego Padres

Aug 19, 2025 - MLB

San Francisco Giants
1 :  5
San Diego Padres

Aug 18, 2025 - MLB

San Francisco Giants
4 :  3
San Diego Padres

Aug 6, 2025 - MLB

San Francisco Giants
4 :  2
Pittsburgh Pirates

Aug 5, 2025 - MLB

San Francisco Giants
8 :  1
Pittsburgh Pirates
Milwaukee Brewers
Milwaukee Brewers Latest matches
L W L L L W
Victories

2/6 (33%)

Defeats

4/6 (67%)

Aug 21, 2025 - MLB

Milwaukee Brewers
4 :  1
Chicago Cubs

Aug 20, 2025 - MLB

Milwaukee Brewers
3 :  4
Chicago Cubs

Aug 19, 2025 - MLB

Milwaukee Brewers
1 :  4
Chicago Cubs

Aug 19, 2025 - MLB

Milwaukee Brewers
4 :  6
Chicago Cubs

Aug 18, 2025 - MLB

Milwaukee Brewers
7 :  0
Chicago Cubs

Aug 17, 2025 - MLB

Milwaukee Brewers
2 :  3
Cincinnati Reds
W W W W W W
Victories

6/6 (100%)

Defeats

0/6 (0%)

Aug 13, 2025 - MLB

Pittsburgh Pirates
5 :  12
Milwaukee Brewers

Aug 12, 2025 - MLB

Pittsburgh Pirates
0 :  14
Milwaukee Brewers

Aug 11, 2025 - MLB

Pittsburgh Pirates
1 :  7
Milwaukee Brewers

Aug 10, 2025 - MLB

New York Mets
6 :  7
Milwaukee Brewers

Aug 9, 2025 - MLB

New York Mets
4 :  7
Milwaukee Brewers

Aug 8, 2025 - MLB

New York Mets
2 :  3
Milwaukee Brewers
L W L L W L
Victories

2/6 (33%)

Defeats

4/6 (67%)

Aug 21, 2025 - MLB

Milwaukee Brewers
4 :  1
Chicago Cubs

Aug 20, 2025 - MLB

Milwaukee Brewers
3 :  4
Chicago Cubs

Aug 19, 2025 - MLB

Milwaukee Brewers
1 :  4
Chicago Cubs

Aug 19, 2025 - MLB

Milwaukee Brewers
4 :  6
Chicago Cubs

Aug 18, 2025 - MLB

Milwaukee Brewers
7 :  0
Chicago Cubs

Aug 17, 2025 - MLB

Milwaukee Brewers
2 :  3
Cincinnati Reds

San Francisco Giants against Milwaukee Brewers : Head to Head (H2H)

San Francisco Giants

67 %

Milwaukee Brewers

33 %

Apr 24, 2025 - MLB

Milwaukee Brewers
5 :  6
San Francisco Giants

Apr 23, 2025 - MLB

Milwaukee Brewers
2 :  4
San Francisco Giants

Apr 22, 2025 - MLB

Milwaukee Brewers
11 :  3
San Francisco Giants

Apr 21, 2025 - MLB

Milwaukee Brewers
2 :  5
San Francisco Giants

Mar 14, 2025 - MLB Spring Training

San Francisco Giants
5 :  11
Milwaukee Brewers

Feb 28, 2025 - MLB Spring Training

Milwaukee Brewers
2 :  9
San Francisco Giants

San Francisco Giants - Milwaukee Brewers Key Points

  1. The Giants struck out 11 times in their last loss
  2. Giants win the 2025 series against the Brewers 3-1
  3. 31-12: Brewers record as home betting favorites in 2025
  4. Brewers, second-most stolen bases in MLB this season

Our San Francisco Giants vs Milwaukee Brewers Prediction

Jose Quintana will start for the Brewers on Friday, amid a solid season for the Colombian, where he surpassed 100 innings pitched. His record is 10-4, and in his last 12 innings pitched, he only allowed two ERs.

The Giants will respond with Carson Whisenhunt, a rookie who has posted a 5.02 ERA in 14.1 innings pitched this season; they have allowed five HRs.

Our prediction for Brewers vs Giants is: Brewers -1.5.

Prediction:

 

Brewers -1.5.

+122
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San Francisco Giants vs Milwaukee Brewers Picks