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by Erik Gibbs in MLB Picks
The San Francisco Giants open a critical four-game series tonight on the road against the Los Angeles Dodgers, marking an important stretch as both clubs look to solidify their postseason positioning. San Francisco enters the matchup with an even 76–76 record, finally breaking out of a prolonged losing skid after a hard-fought extra-inning win against the Arizona Diamondbacks on Wednesday.
That 11th-inning surge gave the Giants a much-needed confidence boost as they try to stay relevant in the Wild Card picture. Following this divisional battle, San Francisco will return home to host the St. Louis Cardinals in another series with postseason implications.
The Dodgers, meanwhile, continue to set the pace in the National League West despite a few recent setbacks. They come into tonight with 85 victories, narrowly ahead of the competition, and looking to shake off a brief two-game slump. Los Angeles responded in a big way in their last outing, shutting down the Philadelphia Phillies in a 5–0 win.
That victory not only reaffirmed their status as one of the toughest teams in the league but also gave them momentum heading into a divisional rivalry that always carries extra weight. After finishing this set with San Francisco, the Dodgers will hit the road to take on the Arizona Diamondbacks.
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San Francisco Giants vs Los Angeles Dodgers Form
Table
| Teams | % | P | W | L |
|---|---|---|---|---|
|
5
|
0.559 | 152 | 85 | 67 |
|
16
|
0.5 | 152 | 76 | 76 |
San Francisco Giants and Los Angeles Dodgers Latest Matches
2/6 (33%)
4/6 (67%)
Sep 17, 2025 - MLB
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3/6 (50%)
3/6 (50%)
Sep 14, 2025 - MLB
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Sep 10, 2025 - MLB
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2/6 (33%)
4/6 (67%)
Sep 17, 2025 - MLB
Sep 16, 2025 - MLB
Sep 15, 2025 - MLB
Sep 7, 2025 - MLB
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Sep 5, 2025 - MLB
3/6 (50%)
3/6 (50%)
Sep 17, 2025 - MLB
Sep 16, 2025 - MLB
Sep 15, 2025 - MLB
Sep 14, 2025 - MLB
Sep 13, 2025 - MLB
Sep 12, 2025 - MLB
4/6 (67%)
2/6 (33%)
Sep 17, 2025 - MLB
Sep 16, 2025 - MLB
Sep 15, 2025 - MLB
Sep 10, 2025 - MLB
Sep 9, 2025 - MLB
Sep 8, 2025 - MLB
3/6 (50%)
3/6 (50%)
Sep 14, 2025 - MLB
Sep 13, 2025 - MLB
Sep 12, 2025 - MLB
Sep 7, 2025 - MLB
Sep 6, 2025 - MLB
Sep 5, 2025 - MLB
San Francisco Giants against Los Angeles Dodgers : Head to Head (H2H)
33 %
67 %
Sep 14, 2025 - MLB
Sep 13, 2025 - MLB
Sep 12, 2025 - MLB
Jul 13, 2025 - MLB
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San Francisco Giants - Los Angeles Dodgers Key Points
- The Dodgers are 7-1 in their last 8 home games vs. the Giants after a home win
- The Giants are 0-9 in their last 9 games vs. the Dodgers after a win
- The Dodgers are 5-1 ATS in their last 6 games vs. NL West teams
- The Giants are 0-10 ATS in their last 10 Thursday games vs. teams with a winning record
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Our San Francisco Giants vs Los Angeles Dodgers Prediction
On the mound, the Giants will turn to their ace, Logan Webb, who has been one of the more consistent arms in the National League. Webb comes into this game with a 14–10 record, a respectable 3.34 ERA, and an impressive 206 strikeouts. However, his track record against the Dodgers has been shaky at best.
In his last five outings versus Los Angeles, Webb has posted a 6.35 ERA despite recording 25 strikeouts. While he has managed to split decisions in those games, the numbers suggest the Dodgers’ lineup has found ways to exploit his pitching style.
Opposing him is Yoshinobu Yamamoto, the Dodgers’ standout right-hander who has impressed in his first big-league campaign. Yamamoto holds an 11–8 record paired with a sharp 2.66 ERA and 187 strikeouts, showing his ability to dominate lineups across the league.
Against San Francisco, his limited career sample shows a 0–1 mark with a 3.70 ERA and 27 strikeouts. Though the Giants have put up some resistance, Yamamoto’s ability to limit damage has generally kept Los Angeles in favorable positions.
The matchup boils down to whether Webb can overcome his struggles against a Dodgers team that has consistently handled him. The Giants may be clawing their way back into contention, but the Dodgers’ deep and balanced offense, paired with Yamamoto’s effectiveness, makes this a daunting challenge. If Los Angeles finds early success against Webb, San Francisco could face an uphill battle right out of the gate.
This opening game sets the tone for the rest of the series, and with both teams having plenty on the line, fans can expect a highly competitive, playoff-like atmosphere at Dodger Stadium. Our prediction for LA Dodgers vs. San Francisco Giants: Over 7.5 runs.
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