San Francisco 49ers vs Indianapolis Colts Prediction & Picks - NFL
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by Carlos Zabala in NFL Picks
The 49ers made the most of their bye week, defeating the Titans 37-24 the following week, aided by three touchdown passes from Purdy. Purdy completed 23 of his 30 passes, a clear indication that he is fully recovered from his toe injury. With the win against Tennessee, the 49ers need only one more victory to secure a playoff spot, which they will pursue on Monday, December 22, when they are 5.5-point favorites to beat the Colts.
Indianapolis, with an 8-6 record after a promising start, is seeing its playoff hopes slip away after losing its last four games against the Chiefs, Texans, Jaguars, and Seahawks. The Colts lost a close game 16-18 against Seattle. At 44 years old, incredibly, it's Phillip Rivers who, as quarterback, is leading the Indianapolis offense after Daniel Jones' devastating season-ending injury.
While the age difference between the 49ers' and Colts' quarterbacks is significant, it's also a duel between two of the NFL's best running backs. Jonathan Taylor of the Colts leads the league with 1,443 rushing yards and 18 touchdowns. San Francisco's McCaffrey isn't far behind with 14 touchdowns.
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San Francisco 49ers vs Indianapolis Colts Form
Table
| Teams | % | P | W | D | L |
|---|---|---|---|---|---|
|
9
|
0.714 | 14 | 10 | 0 | 4 |
|
14
|
0.571 | 14 | 8 | 0 | 6 |
San Francisco 49ers and Indianapolis Colts Latest Matches
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San Francisco 49ers - Indianapolis Colts Key Points
- The Colts have always beaten the 49ers in four meetings since 2009
- Philip Rivers threw 27 passes against the Seahawks, completing 18
- The 49ers rank fourth in the NFL in passing yards with 246.1
- The 49ers' out-and-out record this season is 8-5-1
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Our San Francisco 49ers vs Indianapolis Colts Prediction
It seems the momentum for the game at Lucas Oil Stadium belongs entirely to the 49ers. Since Purdy's return, he's not only been in excellent form, but he's also boosted McCaffrey's performance. After their visit to Indianapolis, the Niners will close out the season against the Bears and Seahawks, so a win on Monday would ensure they don't face any last-minute scares in Weeks 17 and 18.
Rivers, 44, looked surprisingly solid in his first snaps in five years; he himself said he's not so much concerned with improving but rather with winning at all costs, given the Colts' desperate need for victories. However, the 49ers' defense could pose a significant challenge for the veteran.
Our prediction for Colts vs 49ers is: 49ers -5.5.
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