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by Lou Aguila in MLB Picks
The Seattle Mariners have won by at least two runs in 8 of their last 10 meetings with the San Diego Padres.
Will the Mariners regain their winning form and reestablish their dominance over the Padres in the final game of their series on Wednesday at T-Mobile Park?
Seattle’s five-game winning streak against San Diego came to an end on Tuesday as the Padres held on to a 6-5 win in Game 2. The Padres raced to an early 5-0 lead behind an RBI single from Xander Boegarts and a grand slam from Ramon Laureano in the first inning. The Mariners responded with six unanswered runs courtesy of back-to-back three-run homers from Randy Arozarena and Eugenio Suarez in the 5th inning to take the lead at 6-5. However, the Padres struck back as Jake Cronenworth and Freddy Fermin drove in a run each to retake the lead at 7-6. The Mariners never scored again as the Padres’ bullpen shut them down in the final four innings of the match.
Had they won the game, Seattle would have narrowed Houston’s lead to a half game. Instead, the Mariners (71-62) are trailing the Astros (72-60) by 1.5 games in the AL West title race. San Diego (75-58), meanwhile, moved one game within the LA Dodgers (76-58) in the NL West standings.
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San Diego Padres vs Seattle Mariners Form
Table
| Teams | % | P | W | L |
|---|---|---|---|---|
|
7
|
0.564 | 133 | 75 | 58 |
|
12
|
0.534 | 133 | 71 | 62 |
San Diego Padres and Seattle Mariners Latest Matches
4/6 (67%)
2/6 (33%)
Aug 26, 2025 - MLB
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5/6 (83%)
1/6 (17%)
Aug 24, 2025 - MLB
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2/6 (33%)
4/6 (67%)
Aug 26, 2025 - MLB
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Aug 13, 2025 - MLB
3/6 (50%)
3/6 (50%)
Aug 26, 2025 - MLB
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Aug 20, 2025 - MLB
4/6 (67%)
2/6 (33%)
Aug 26, 2025 - MLB
Aug 25, 2025 - MLB
Aug 24, 2025 - MLB
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Aug 10, 2025 - MLB
1/6 (17%)
5/6 (83%)
Aug 20, 2025 - MLB
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Aug 15, 2025 - MLB
San Diego Padres against Seattle Mariners : Head to Head (H2H)
33 %
67 %
Aug 26, 2025 - MLB
Aug 25, 2025 - MLB
May 18, 2025 - MLB
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Mar 24, 2025 - MLB Spring Training
San Diego Padres - Seattle Mariners Key Points
- San Diego is 6-2 SU in its last 8 games.
- San Diego is 2-5 SU in its last 7 games when playing on the road against Seattle.
- Seattle is 3-7 SU in its last 10 games.
- Seattle is 5-2 SU in its last 7 games when playing at home against San Diego.
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Our San Diego Padres vs Seattle Mariners Prediction
I am taking the Padres to win again in Game 3. San Diego may have figured out how to outscore the Mariners after bombarding them with seven runs in Game 2. Moreover, Yu Darvish (3-3, 5.36 ERA) has always pitched well against the Mariners. The Japanese pitcher has surrendered a total of two earned runs across three starts against the Mariners, blanking them twice.
Averaging 6.3 runs per game in their last five games, Seattle remains a dangerous team because it can explode at any time. Bryan Woo, the project started on Wednesday, has been stellar in his recent starts and is expected to test the Padres’ batting corps that is still missing the service of Jackson Merrill. San Diego is in for another tough battle in Game 3, but yesterday’s offensive breakthrough against Seattle makes them my high-risk, high-reward pick of the day.
Our betting prediction for the San Diego Padres vs. the Seattle Mariners: the Padres will win.
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All tips are fully researched and given in good faith, but profits cannot be guaranteed.
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