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by Lou Aguila in MLB Picks
Listed at -115, the Seattle Mariners will attempt to push their win streak against the San Diego Padres to six games in Game 2 of their series on Tuesday at T-Mobile Park.
The Mariners extended their head-to-head dominance over the Padres, capturing their fifth straight win over the No.2 team in the NL West behind a prolific scoring night from their offense. Seattle improved its slate to 71-61, trailing the 72-59 Houston Astros – the current pace-setters in the AL West - by 1.5 games with barely a month left in the regular season. Averaging 4.6 runs per game this season, the Mariners have already scored 20 runs in their last two games.
The Padres’ elite pitching has been nonexistent in their last two games. San Diego conceded nine runs to the Mariners in Game 1, roughly 24 hours after surrendering eight runs in a 2-8 loss to the Los Angeles Dodgers in their series finale. San Diego boasts a 3.59 ERA in their last five games, but that figure dipped over the last five games to 4.50 ERA following two consecutive bad nights on the bump.
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San Diego Padres vs Seattle Mariners Form
Table
| Teams | % | P | W | L |
|---|---|---|---|---|
|
7
|
0.561 | 132 | 74 | 58 |
|
11
|
0.538 | 132 | 71 | 61 |
San Diego Padres and Seattle Mariners Latest Matches
4/6 (67%)
2/6 (33%)
Aug 25, 2025 - MLB
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Aug 20, 2025 - MLB
5/6 (83%)
1/6 (17%)
Aug 24, 2025 - MLB
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Aug 22, 2025 - MLB
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Aug 19, 2025 - MLB
2/6 (33%)
4/6 (67%)
Aug 25, 2025 - MLB
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3/6 (50%)
3/6 (50%)
Aug 25, 2025 - MLB
Aug 24, 2025 - MLB
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Aug 19, 2025 - MLB
5/6 (83%)
1/6 (17%)
Aug 25, 2025 - MLB
Aug 24, 2025 - MLB
Aug 23, 2025 - MLB
Aug 22, 2025 - MLB
Aug 10, 2025 - MLB
Aug 9, 2025 - MLB
1/6 (17%)
5/6 (83%)
Aug 20, 2025 - MLB
Aug 19, 2025 - MLB
Aug 18, 2025 - MLB
Aug 17, 2025 - MLB
Aug 16, 2025 - MLB
Aug 15, 2025 - MLB
San Diego Padres against Seattle Mariners : Head to Head (H2H)
33 %
67 %
Aug 25, 2025 - MLB
May 18, 2025 - MLB
May 17, 2025 - MLB
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Mar 24, 2025 - MLB Spring Training
Mar 15, 2025 - MLB Spring Training
San Diego Padres - Seattle Mariners Key Points
- San Diego is 0-5 SU in its last 5 games against Seattle.
- San Diego is 1-4 SU in its last 5 games on the road.
- Seattle is 10-1 SU in its last 11 games at home.
- Seattle is 5-1 SU in its last 6 games when playing at home against San Diego.
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Our San Diego Padres vs Seattle Mariners Prediction
It's safe to say the Mariners own the Padres. They have won the last five meetings against San Diego and nine of their last 10 clashes. Moreover, they won by at least two runs in all nine victories, underscoring the Mariners’ recent dominance over the Padres. Luis Castillo, the projected starter for the Mariners on Tuesday, is coming off a disappointing mound appearance against the Philadelphia Phillies on August 20. In this game, Castillo surrendered three earned runs and 10 hits over four innings in a 2-4 loss. Despite his shaky form as of late, Castillo should be fine as long as the Mariners’ offense continues to deliver the goods behind the plate.
Seattle averages 5.4 runs per game in its last five games and 6.33 runs per game in its last three meetings with the Padres. San Diego won in 4 of Dylan Cease’s last 5 starts. However, the Padres have struggled offensively against the Mariners in their past three meetings, averaging 2.67 runs per game.
I am taking the Mariners to win straight up at -115. Their head-to-head success over the Padres in the past five games, along with San Diego’s inconsistent pitching recently, make Seattle, 40-26 at home this season, a firm moneyline pick in this match.
Our betting prediction for the San Diego Padres vs. the Seattle Mariners: the Mariners will win.
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All tips are fully researched and given in good faith, but profits cannot be guaranteed.
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