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by Lou Aguila in MLB Picks
The Pittsburgh Pirates will play host to the San Diego Padres starting Friday at PNC Park.
The Pirates dropped to 12-20 after winning just one match in a three-game series with the Chicago Cubs this week. As usual, Pittsburgh struggled anew on the mound, allowing the Cubs to outscore them 9-0 in Game 1 and 8-3 in Game 3. The Pirates carry the 10th worst ERA in baseball at 4.23 and post a .224 batting average – the fifth worst in the MLB.
The Padres ended their four-game win drought with back-to-back victories over division rivals the San Francisco Giants. San Diego, which is averaging 3.1 runs per game over its last five games, outscored the Giants by relying heavily on its pitching staff, especially its vaunted bullpen, which boasts a 1.77 ERA.
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San Diego Padres vs Pittsburgh Pirates Form
Table
Teams | % | P | W | L |
---|---|---|---|---|
3
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0.633 | 30 | 19 | 11 |
28
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0.375 | 32 | 12 | 20 |
San Diego Padres and Pittsburgh Pirates Latest Matches

2/6 (33%)
4/6 (67%)
Apr 30, 2025 - MLB
Apr 29, 2025 - MLB
Apr 27, 2025 - MLB
Apr 26, 2025 - MLB
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Apr 23, 2025 - MLB
3/6 (50%)
3/6 (50%)
Apr 30, 2025 - MLB
Apr 29, 2025 - MLB
Apr 27, 2025 - MLB
Apr 26, 2025 - MLB
Apr 25, 2025 - MLB
Apr 16, 2025 - MLB
2/6 (33%)
4/6 (67%)
Apr 23, 2025 - MLB
Apr 22, 2025 - MLB
Apr 21, 2025 - MLB
Apr 20, 2025 - MLB
Apr 19, 2025 - MLB
Apr 18, 2025 - MLB

2/6 (33%)
4/6 (67%)
May 1, 2025 - MLB
Apr 30, 2025 - MLB
Apr 29, 2025 - MLB
Apr 27, 2025 - MLB
Apr 26, 2025 - MLB
Apr 25, 2025 - MLB
1/6 (17%)
5/6 (83%)
May 1, 2025 - MLB
Apr 30, 2025 - MLB
Apr 29, 2025 - MLB
Apr 20, 2025 - MLB
Apr 19, 2025 - MLB
Apr 18, 2025 - MLB
3/6 (50%)
3/6 (50%)
Apr 27, 2025 - MLB
Apr 26, 2025 - MLB
Apr 25, 2025 - MLB
Apr 24, 2025 - MLB
Apr 23, 2025 - MLB
Apr 22, 2025 - MLB
San Diego Padres against Pittsburgh Pirates : Head to Head (H2H)
100 %
0 %
Aug 14, 2024 - MLB
Aug 13, 2024 - MLB
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Aug 8, 2024 - MLB
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Aug 6, 2024 - MLB
San Diego Padres - Pittsburgh Pirates Key Points
- San Diego is 2-4 SU in its last 6 games.
- San Diego is 6-0 SU in its last 6 games against Pittsburgh.
- Pittsburgh is 1-4 SU in its last 5 games.
- Pittsburgh is 1-5 SU in its last 6 games at home.
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Our San Diego Padres vs Pittsburgh Pirates Prediction
The Padres are sending Dylan Cease (5.68 ERA) to the mound in Game 1 vs. the Pirates. Cease, who surrendered two earned runs in his last three starts, will match up against Pirates starter Mitch Keller (4.50 ERA). The Padres’ offense might be subpar at best this season, but I still like their chances against a much worse run-scoring team in the Pirates, who are scoring 2.7 runs per game in their last five assignments. Moreover, Keller squandered eight runs the last time he started against the Padres on August 14, 2014. Our betting prediction for the San Diego Padres vs. Pittsburgh Pirates: Padres -1.5 Runs
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All tips are fully researched and given in good faith, but profits cannot be guaranteed.

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