Saint Louis City SC vs Charlotte FC Prediction & Picks - Major League Soccer

USA - Major League Soccer

Saint Louis City SC
2/21/26 14:30
Charlotte FC

Prediction:

 

Pep Biel to Score

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 by Mikaella McIntosh | in Major League Soccer Picks

The first game of the 2026 MLS season kicks off on Saturday afternoon, where St Louis City and Charlotte take to the stage in Missouri. 

Charlotte had a top-rate 2025 season, finishing 4th in the Eastern Conference, reaching the playoffs, plus scoring in all but three away games. The same can’t be affirmed for St Louis City, concluding the season ranked 13th in the Western Conference. Saturday marks the start of a fresh season, which will especially be cherished by the home side. Will either team be able to get a crucial headstart with a victory?

When comparing their pre-season friendlies, it’s evident which team is coming into the next chapter with more confidence. The visiting team have won three out of four, scoring a total of seven goals. In contrast, St Louis City succeeded in just one out of four, conceding eight goals.

Up to $200 to bet on Saint Louis City SC - Charlotte FC! 

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Saint Louis City SC vs Charlotte FC Form

Table

Teams Pts P W D L GD
14 Charlotte FC
21 15 6 3 6 +1
22 Saint Louis City SC
16 14 4 4 6 -4

Saint Louis City SC and Charlotte FC Latest Matches

Saint Louis City SC
Saint Louis City SC Latest matches
D W W L W D
Victories

3/6 (50%)

Draw

2/6 (33%)

Defeats

1/6 (17%)

Average stats (Last 6 matchs)

3.17 Total goals
67% BTTS
1.83 Goals scored
1.33 Goals conceded
67% Over 2.5
33% Under 2.5

Oct 18, 2025 - Major League Soccer

Saint Louis City SC
2 :  2
Real Salt Lake

Oct 4, 2025 - Major League Soccer

Austin FC
1 :  3
Saint Louis City SC

Sep 27, 2025 - Major League Soccer

Saint Louis City SC
0 :  3
Los Angeles FC

Sep 20, 2025 - Major League Soccer

San Jose Earthquakes
1 :  3
Saint Louis City SC

Sep 13, 2025 - Major League Soccer

CF Montreal
0 :  2
Saint Louis City SC

Sep 6, 2025 - Major League Soccer

Saint Louis City SC
1 :  1
FC Dallas
L W L D L D
Victories

1/6 (17%)

Draw

2/6 (33%)

Defeats

3/6 (50%)

Average stats (Last 6 matchs)

3.5 Total goals
83% BTTS
1.5 Goals scored
2 Goals conceded
83% Over 2.5
17% Under 2.5

Oct 18, 2025 - Major League Soccer

Saint Louis City SC
2 :  2
Real Salt Lake

Sep 27, 2025 - Major League Soccer

Saint Louis City SC
0 :  3
Los Angeles FC

Sep 6, 2025 - Major League Soccer

Saint Louis City SC
1 :  1
FC Dallas

Aug 30, 2025 - Major League Soccer

Saint Louis City SC
2 :  3
Houston Dynamo

Aug 9, 2025 - Major League Soccer

Saint Louis City SC
3 :  1
Nashville SC

Jul 30, 2025 - Clubs Friendlies

Saint Louis City SC
1 :  2
Aston Villa
L L L W W W
Victories

3/6 (50%)

Draw

0/6 (0%)

Defeats

3/6 (50%)

Average stats (Last 6 matchs)

3.83 Total goals
67% BTTS
2 Goals scored
1.83 Goals conceded
83% Over 2.5
17% Under 2.5

Oct 4, 2025 - Major League Soccer

Austin FC
1 :  3
Saint Louis City SC

Sep 20, 2025 - Major League Soccer

San Jose Earthquakes
1 :  3
Saint Louis City SC

Sep 13, 2025 - Major League Soccer

CF Montreal
0 :  2
Saint Louis City SC

Aug 23, 2025 - Major League Soccer

Vancouver Whitecaps
3 :  2
Saint Louis City SC

Aug 16, 2025 - Major League Soccer

Chicago Fire
3 :  2
Saint Louis City SC

Jul 19, 2025 - Major League Soccer

FC Dallas
3 :  0
Saint Louis City SC
Charlotte FC
Charlotte FC Latest matches
L W W L D L
Victories

2/6 (33%)

Draw

1/6 (17%)

Defeats

3/6 (50%)

Average stats (Last 6 matchs)

2.17 Total goals
33% BTTS
0.83 Goals scored
1.33 Goals conceded
33% Over 2.5
67% Under 2.5

Nov 7, 2025 - Major League Soccer

Charlotte FC
1 :  3
New York City

Nov 1, 2025 - Major League Soccer

New York City
0 :  0
Charlotte FC

Oct 28, 2025 - Major League Soccer

Charlotte FC
0 :  1
New York City

Oct 18, 2025 - Major League Soccer

Charlotte FC
2 :  0
Philadelphia Union

Oct 4, 2025 - Major League Soccer

DC United
0 :  1
Charlotte FC

Sep 27, 2025 - Major League Soccer

Charlotte FC
1 :  4
CF Montreal
W W L W L L
Victories

3/6 (50%)

Draw

0/6 (0%)

Defeats

3/6 (50%)

Average stats (Last 6 matchs)

2.67 Total goals
33% BTTS
1.33 Goals scored
1.33 Goals conceded
50% Over 2.5
50% Under 2.5

Nov 7, 2025 - Major League Soccer

Charlotte FC
1 :  3
New York City

Oct 28, 2025 - Major League Soccer

Charlotte FC
0 :  1
New York City

Oct 18, 2025 - Major League Soccer

Charlotte FC
2 :  0
Philadelphia Union

Sep 27, 2025 - Major League Soccer

Charlotte FC
1 :  4
CF Montreal

Sep 13, 2025 - Major League Soccer

Charlotte FC
3 :  0
Inter Miami

Aug 24, 2025 - Major League Soccer

Charlotte FC
1 :  0
New York Red Bulls
W W W L W D
Victories

4/6 (67%)

Draw

1/6 (17%)

Defeats

1/6 (17%)

Average stats (Last 6 matchs)

1.5 Total goals
17% BTTS
1 Goals scored
0.5 Goals conceded
17% Over 2.5
83% Under 2.5

Nov 1, 2025 - Major League Soccer

New York City
0 :  0
Charlotte FC

Oct 4, 2025 - Major League Soccer

DC United
0 :  1
Charlotte FC

Sep 20, 2025 - Major League Soccer

New York City
2 :  0
Charlotte FC

Aug 30, 2025 - Major League Soccer

New England Revolution
1 :  2
Charlotte FC

Aug 10, 2025 - Major League Soccer

FC Cincinnati
0 :  1
Charlotte FC

Aug 7, 2025 - Leagues Cup

Monterrey
0 :  2
Charlotte FC

Saint Louis City SC against Charlotte FC Lineups: Starting 11

Saint Louis City SC

Formation : 3 - 4 - 1 - 2

1
R. Burki
99
J. Orozco
21
D. Polvara
32
T. Baumgartl
6
C. Wallem
8
C. Durkin
24
D. Edelman
20
R. Santos
17
M. Hartel
77
J. Sang-bin
11
S. Becher
9
I. Gorno
10
W. Zaha
16
P. Biel
11
L. Abada
17
L. De La Torre
8
A. Westwood
15
H. Toffolo
3
T. Ream
4
A. Privett
14
N. Byrne
1
K. Kahlina

Formation : 4 - 2 - 3 - 1

Charlotte FC

Substitutes

Saint Louis City SC
Saint Louis City SC
Goalkeeper

B. Lundt

Defender

T. Totland

R. Santos 90'

L. MacNaughton

D. Polvara 84'

K. Hiebert

Midfielder

M. Perez

C. Durkin 83'

C. Pompeu

Forward

M. Joyner

C. Teuchert

S. Becher 90'

B. McSorley

J. Sang-bin 59'

Charlotte FC
Charlotte FC
Goalkeeper

T. Miller

Defender

M. Agyemang

J. Neeley

D. Schnegg

H. Toffolo 70'

Midfielder

D. Diani

L. De La Torre 69'

B. Bronico

Forward

A. Goodwin

K. Vargas

L. Abada 69'

T. Smalls

I. Gorno 88'

Missing players

Saint Louis City SC
Saint Louis City SC
Defender

F. Fall

Midfielder

E. Lowen

T. Ostrak

T. Pearce

Charlotte FC
Charlotte FC
Defender

H. Kessler

Most goals and assists

CD Huachipato Saint Louis City SC
CD Huachipato Charlotte FC
Top Goalscorer
Germany M. Hartel (3 Goals)
Top Goalscorer
Spain P. Biel (7 Goals)
Best assists
USA S. Becher (3 Assists)
Best assists
Spain P. Biel (4 Assists)

Saint Louis City SC - Charlotte FC Key Points

  1. Biel scored ten goals for Charlotte last season.
  2. Charlotte scored in all but three away games last season.
  3. Pep Biel averaged 0.45 goals per 90 minutes in 2025.
  4. Biel averaged 2.42 shots per 90 minutes in the MLS last season.
Up to $200 to bet on Saint Louis City SC - Charlotte FC! 

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Our Saint Louis City SC vs Charlotte FC Prediction

On loan from Olympiacos, Biel made 26 appearances last season for Charlotte, and clearly they were very impressed with his performance as the move has been made permanent. And rightly so, since the Spaniard had 21 direct goal involvements in 2025.

Whilst Charlotte scored in 14 out of 17 games on the road last season, St Louis City kept a clean sheet in just 18% of their matches, both in total and at home, averaging 1.71 goals conceded per game. 

Out of Dean Smith’s regular players, Biel averaged one of the highest number of shots per game last season (2.42). We can see how crucial the forward is for Charlotte’s offensive approach, recording the highest direct goal contributions, hence why I like the early odds for Biel to score.

Our Saint Louis City vs Charlotte pick: Pep Biel to Score.

Prediction:

 

Pep Biel to Score

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$200 offered for betting!

All tips are fully researched and given in good faith, but profits cannot be guaranteed.

Saint Louis City SC vs Charlotte FC Picks