San Antonio Spurs vs Portland Trail Blazers Prediction & Picks - NBA

USA - NBA

San Antonio Spurs
4/28/26 21:30
Portland Trail Blazers

Prediction:

 

San Antonio Spurs -11.5

-115
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 by Matt Lowrimore | in NBA Picks

Tuesday's NBA slate will feature three games, including a crucial Game 5 in the Western Conference series between the San Antonio Spurs and the Portland Trail Blazers. Let's take a look at the match statistics and predictions for this game between the Spurs and the Trail Blazers.

After stealing Game 2 on the road, Portland failed to take advantage, losing both Game 3 and Game 4 at home. As a result, the Trail Blazers find themselves trailing in the series 3-1, making this a must-win game if they are going to avoid elimination. 

As good as Portland has played throughout this series, they simply have not had much of an answer for Victor Wembanyama and the trio of guards the Spurs have thrown at them. 

One of the biggest problems Portland has had in this series is the inability to play a complete game. The Trail Blazers were leading Game 3 by 15 points and lost, then were leading Game 4 by 17 points and lost again. Given that, there should not be much confidence in Portland to claw its way back into this series.

San Antonio Spurs vs Portland Trail Blazers Form

San Antonio Spurs and Portland Trail Blazers Latest Matches

San Antonio Spurs
San Antonio Spurs Latest matches
W L W L W W
Victories

4/6 (67%)

Defeats

2/6 (33%)

Apr 26, 2026 - NBA

Portland Trail Blazers
93 :  114
San Antonio Spurs

Apr 24, 2026 - NBA

Portland Trail Blazers
108 :  120
San Antonio Spurs

Apr 21, 2026 - NBA

San Antonio Spurs
103 :  106
Portland Trail Blazers

Apr 19, 2026 - NBA

San Antonio Spurs
111 :  98
Portland Trail Blazers

Apr 12, 2026 - NBA

San Antonio Spurs
118 :  128
Denver Nuggets

Apr 10, 2026 - NBA

San Antonio Spurs
139 :  120
Dallas Mavericks
W W W L W L
Victories

4/6 (67%)

Defeats

2/6 (33%)

Apr 21, 2026 - NBA

San Antonio Spurs
103 :  106
Portland Trail Blazers

Apr 19, 2026 - NBA

San Antonio Spurs
111 :  98
Portland Trail Blazers

Apr 12, 2026 - NBA

San Antonio Spurs
118 :  128
Denver Nuggets

Apr 10, 2026 - NBA

San Antonio Spurs
139 :  120
Dallas Mavericks

Apr 8, 2026 - NBA

San Antonio Spurs
112 :  101
Portland Trail Blazers

Apr 6, 2026 - NBA

San Antonio Spurs
115 :  102
Philadelphia 76ers
W W W L W W
Victories

5/6 (83%)

Defeats

1/6 (17%)

Apr 26, 2026 - NBA

Portland Trail Blazers
93 :  114
San Antonio Spurs

Apr 24, 2026 - NBA

Portland Trail Blazers
108 :  120
San Antonio Spurs

Apr 4, 2026 - NBA

Denver Nuggets
136 :  134
San Antonio Spurs

Apr 2, 2026 - NBA

LA Clippers
99 :  118
San Antonio Spurs

Apr 1, 2026 - NBA

Golden State Warriors
113 :  127
San Antonio Spurs

Mar 28, 2026 - NBA

Milwaukee Bucks
95 :  127
San Antonio Spurs
Portland Trail Blazers
Portland Trail Blazers Latest matches
W W L W L L
Victories

3/6 (50%)

Defeats

3/6 (50%)

Apr 26, 2026 - NBA

Portland Trail Blazers
93 :  114
San Antonio Spurs

Apr 24, 2026 - NBA

Portland Trail Blazers
108 :  120
San Antonio Spurs

Apr 21, 2026 - NBA

San Antonio Spurs
103 :  106
Portland Trail Blazers

Apr 19, 2026 - NBA

San Antonio Spurs
111 :  98
Portland Trail Blazers

Apr 14, 2026 - NBA

Phoenix Suns
110 :  114
Portland Trail Blazers

Apr 12, 2026 - NBA

Portland Trail Blazers
122 :  110
Sacramento Kings
W W W W L L
Victories

4/6 (67%)

Defeats

2/6 (33%)

Apr 26, 2026 - NBA

Portland Trail Blazers
93 :  114
San Antonio Spurs

Apr 24, 2026 - NBA

Portland Trail Blazers
108 :  120
San Antonio Spurs

Apr 12, 2026 - NBA

Portland Trail Blazers
122 :  110
Sacramento Kings

Apr 10, 2026 - NBA

Portland Trail Blazers
116 :  97
LA Clippers

Apr 2, 2026 - NBA

Portland Trail Blazers
118 :  106
New Orleans Pelicans

Mar 29, 2026 - NBA

Portland Trail Blazers
123 :  88
Washington Wizards
W L L W L W
Victories

3/6 (50%)

Defeats

3/6 (50%)

Apr 21, 2026 - NBA

San Antonio Spurs
103 :  106
Portland Trail Blazers

Apr 19, 2026 - NBA

San Antonio Spurs
111 :  98
Portland Trail Blazers

Apr 14, 2026 - NBA

Phoenix Suns
110 :  114
Portland Trail Blazers

Apr 8, 2026 - NBA

San Antonio Spurs
112 :  101
Portland Trail Blazers

Apr 6, 2026 - NBA

Denver Nuggets
137 :  132
Portland Trail Blazers

Mar 31, 2026 - NBA

LA Clippers
104 :  114
Portland Trail Blazers

San Antonio Spurs against Portland Trail Blazers : Head to Head (H2H)

San Antonio Spurs

67 %

Portland Trail Blazers

33 %

Apr 26, 2026 - NBA

Portland Trail Blazers
93 :  114
San Antonio Spurs

Apr 24, 2026 - NBA

Portland Trail Blazers
108 :  120
San Antonio Spurs

Apr 21, 2026 - NBA

San Antonio Spurs
103 :  106
Portland Trail Blazers

Apr 19, 2026 - NBA

San Antonio Spurs
111 :  98
Portland Trail Blazers

Apr 8, 2026 - NBA

San Antonio Spurs
112 :  101
Portland Trail Blazers

Jan 3, 2026 - NBA

San Antonio Spurs
110 :  115
Portland Trail Blazers

Players list

San Antonio Spurs
San Antonio Spurs
V. Wembanyama D. Vassell

J. Champagnie

S. Castle

D. Fox

Portland Trail Blazers
Portland Trail Blazers
D. Clingan

S. Henderson

J. Holiday

T. Camara

D. Avdija

Substitutes

San Antonio Spurs
San Antonio Spurs
K. Olynyk B. Biyombo M. Plumlee L. Kornet K. Johnson

D. Harper

J. McLaughlin

L. Waters III

H. Barnes

C. Bryant

Portland Trail Blazers
Portland Trail Blazers
Y. Hansen M. Thybulle R. Williams III

B. Wesley

S. Cissoko

S. Sharpe

K. Murray

V. Krejci

J. Grant

San Antonio Spurs - Portland Trail Blazers Key Points

  1. Portland is 1-3 ATS in the series
  2. Portland is averaging 101.3 points per game in the series
  3. San Antonio is averaging 112.0 points per game in the series
  4. San Antonio is shooting 47.1% from the field in the series

Our San Antonio Spurs vs Portland Trail Blazers Prediction

San Antonio is once again the double-digit favorite; however, they still look to be the best betting option. In three wins this series, the Spurs have won by an average margin of 15.3 points per game. Their only loss in the series came in Game 2 when Wembanyama had to exit early with a concussion. 

Aside from that, San Antonio has dominated Portland, scoring an average of 112 points per game compared to Portland, which has averaged 101.3 points per game. Further, the Spurs have shot 47% from the field. Because of how efficient they have been from the field, our San Antonio Spurs vs Portland Trail Blazers prediction is: San Antonio Spurs -11.5.

Prediction:

 

San Antonio Spurs -11.5

-115
$200 offered for betting!

All tips are fully researched and given in good faith, but profits cannot be guaranteed.

San Antonio Spurs vs Portland Trail Blazers Picks