New England Patriots vs Pittsburgh Steelers Prediction & Picks - NFL

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New England Patriots
9/21/25 13:00
Pittsburgh Steelers

Prediction:

 

New England Patriots ML

+105
$150 offered for betting!

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 by Matt Lowrimore | in NFL Picks

Week 3 in the NFL will continue on Sunday, and one of the scheduled games will see the New England Patriots take on the Pittsburgh Steelers. Let’s take a look at the match statistics and predictions for this game between the Patriots and the Steelers.

Pittsburgh enters this game with a record of 1-1, having most recently lost to the Seattle Seahawks in Week 2 by a score of 31-17. The Steelers’ offense had a total of 267 yards, while its defense allowed 395 yards. Quarterback Aaron Rodgers threw for 203 yards, one touchdown, and two interceptions, while running back Jaylen Warren led the team in rushing with 48 yards.

As for New England, they enter this game with a record of 1-1, having most recently beaten the Miami Dolphins in Week 2 by a score of 33-27. The Patriots’ offense had a total of 333 yards, while its defense allowed 358 yards. Quarterback Drake Maye threw for 230 yards and two touchdowns, while also rushing for 31 yards and one touchdown.

New England Patriots vs Pittsburgh Steelers Form

Table

Teams Pts P W L
3 New England Patriots
0.824 17 14 3
12 Pittsburgh Steelers
0.588 17 10 7

New England Patriots and Pittsburgh Steelers Latest Matches

New England Patriots
New England Patriots Latest matches
L L L W L W
Victories

2/6 (33%)

Defeats

4/6 (67%)

Sep 14, 2025 - NFL

Miami Dolphins
27 :  33
New England Patriots

Sep 7, 2025 - NFL

New England Patriots
13 :  20
Las Vegas Raiders

Jan 5, 2025 - NFL

New England Patriots
23 :  16
Buffalo Bills

Dec 28, 2024 - NFL

New England Patriots
7 :  40
Los Angeles Chargers

Dec 22, 2024 - NFL

Buffalo Bills
24 :  21
New England Patriots

Dec 15, 2024 - NFL

Arizona Cardinals
30 :  17
New England Patriots
W L L L W L
Victories

2/6 (33%)

Defeats

4/6 (67%)

Sep 7, 2025 - NFL

New England Patriots
13 :  20
Las Vegas Raiders

Jan 5, 2025 - NFL

New England Patriots
23 :  16
Buffalo Bills

Dec 28, 2024 - NFL

New England Patriots
7 :  40
Los Angeles Chargers

Dec 1, 2024 - NFL

New England Patriots
24 :  25
Indianapolis Colts

Nov 17, 2024 - NFL

New England Patriots
22 :  28
Los Angeles Rams

Oct 27, 2024 - NFL

New England Patriots
25 :  22
New York Jets
L W L L L W
Victories

2/6 (33%)

Defeats

4/6 (67%)

Sep 14, 2025 - NFL

Miami Dolphins
27 :  33
New England Patriots

Dec 22, 2024 - NFL

Buffalo Bills
24 :  21
New England Patriots

Dec 15, 2024 - NFL

Arizona Cardinals
30 :  17
New England Patriots

Nov 24, 2024 - NFL

Miami Dolphins
34 :  15
New England Patriots

Nov 10, 2024 - NFL

Chicago Bears
3 :  19
New England Patriots

Nov 3, 2024 - NFL

Tennessee Titans
20 :  17
New England Patriots
Pittsburgh Steelers
Pittsburgh Steelers Latest matches
L L L L W L
Victories

1/6 (17%)

Defeats

5/6 (83%)

Sep 14, 2025 - NFL

Pittsburgh Steelers
17 :  31
Seattle Seahawks

Sep 7, 2025 - NFL

New York Jets
32 :  34
Pittsburgh Steelers

Jan 11, 2025 - NFL

Baltimore Ravens
28 :  14
Pittsburgh Steelers

Jan 4, 2025 - NFL

Pittsburgh Steelers
17 :  19
Cincinnati Bengals

Dec 25, 2024 - NFL

Pittsburgh Steelers
10 :  29
Kansas City Chiefs

Dec 21, 2024 - NFL

Baltimore Ravens
34 :  17
Pittsburgh Steelers
W W W L L L
Victories

3/6 (50%)

Defeats

3/6 (50%)

Sep 14, 2025 - NFL

Pittsburgh Steelers
17 :  31
Seattle Seahawks

Jan 4, 2025 - NFL

Pittsburgh Steelers
17 :  19
Cincinnati Bengals

Dec 25, 2024 - NFL

Pittsburgh Steelers
10 :  29
Kansas City Chiefs

Dec 8, 2024 - NFL

Pittsburgh Steelers
27 :  14
Cleveland Browns

Nov 17, 2024 - NFL

Pittsburgh Steelers
18 :  16
Baltimore Ravens

Oct 28, 2024 - NFL

Pittsburgh Steelers
26 :  18
New York Giants
L W L L L W
Victories

2/6 (33%)

Defeats

4/6 (67%)

Sep 7, 2025 - NFL

New York Jets
32 :  34
Pittsburgh Steelers

Jan 11, 2025 - NFL

Baltimore Ravens
28 :  14
Pittsburgh Steelers

Dec 21, 2024 - NFL

Baltimore Ravens
34 :  17
Pittsburgh Steelers

Dec 15, 2024 - NFL

Philadelphia Eagles
27 :  13
Pittsburgh Steelers

Dec 1, 2024 - NFL

Cincinnati Bengals
38 :  44
Pittsburgh Steelers

Nov 21, 2024 - NFL

Cleveland Browns
24 :  19
Pittsburgh Steelers

New England Patriots against Pittsburgh Steelers : Head to Head (H2H)

New England Patriots

100 %

Pittsburgh Steelers

0 %

Dec 7, 2023 - NFL

Pittsburgh Steelers
18 :  21
New England Patriots
New England Patriots vs Pittsburgh Steelers Picks

New England Patriots - Pittsburgh Steelers Key Points

  1. The Patriots are 1-1 ATS this season
  2. The Patriots are averaging 23.0 points per game this season
  3. The Steelers are 0-2 ATS this season
  4. The Steelers are allowing 31.5 points per game this season

Our New England Patriots vs Pittsburgh Steelers Prediction

Pittsburgh is the small favorite in this matchup; however, New England looks to be a decent betting option to win this game. Through only two games, the Patriots have been the better team defensively, allowing an average of 23.5 points per game, while the Steelers are allowing an average of 31.5 points per game. 

Further, the Steelers have failed to cover the spread in both of their games, both of which they were a favorite in. The Steelers may have Aaron Rodgers playing quarterback for them, but Patriots quarterback Drake Maye has already been impressive this season and should be able to exploit a Steelers’ defense that has looked bad. For that reason, our New England Patriots vs Pittsburgh Steelers prediction is: New England Patriots ML.

Prediction:

 

New England Patriots ML

+105
$150 offered for betting!

All tips are fully researched and given in good faith, but profits cannot be guaranteed.