Pittsburgh Pirates vs San Diego Padres Prediction & Picks - MLB

USA - MLB

Pittsburgh Pirates
5/31/25 21:40
San Diego Padres

Prediction:

 

Pirates -1.5 Runs

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 by Lou Aguila in MLB Picks

San Diego Padres will go head-to-head with the Pittsburgh Pirates in Game 2 of their series at Petco Park.

The Padres are 4-1 in their last 5 games, averaging 5.7 runs per game but pitching a 4.21 ERA. They are two games behind the Los Angeles Dodgers (35-22) in the National League West standings. Gavin Sheet leads the team with 34 RBIs, while Manny Machado and Fernando Tatis pace the team in home runs (13) and batting average (.314).

The Pirates are 2-3 in their last 5 games to stay in the bottom of the NL Central standings with a 21-37 record. Pittsburgh has enjoyed success offensively, averaging 5.2 runs per game on a .262 batting average. Pittsburgh has also pitched a 3.98 ERA with Paul Skenes leading the team in ERA (2.15), Wins (4) and Strikeouts (77).

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Pittsburgh Pirates vs San Diego Padres Form

Table

Teams % P W L
7
San Diego Padres
San Diego Padres
0.579 57 33 24
28
Pittsburgh Pirates
Pittsburgh Pirates
0.367 60 22 38

Pittsburgh Pirates and San Diego Padres Latest Matches

Pittsburgh Pirates
Pittsburgh Pirates Latest matches
W L L W W L
Victories

3/6 (50%)

Defeats

3/6 (50%)

May 30, 2025 - MLB

Pittsburgh Pirates
2 :  3
San Diego Padres

May 28, 2025 - MLB

Pittsburgh Pirates
10 :  1
Arizona Diamondbacks

May 27, 2025 - MLB

Pittsburgh Pirates
9 :  6
Arizona Diamondbacks

May 26, 2025 - MLB

Pittsburgh Pirates
0 :  5
Arizona Diamondbacks

May 25, 2025 - MLB

Milwaukee Brewers
6 :  5
Pittsburgh Pirates

May 24, 2025 - MLB

Milwaukee Brewers
1 :  2
Pittsburgh Pirates
W W L W W L
Victories

4/6 (67%)

Defeats

2/6 (33%)

May 25, 2025 - MLB

Milwaukee Brewers
6 :  5
Pittsburgh Pirates

May 24, 2025 - MLB

Milwaukee Brewers
1 :  2
Pittsburgh Pirates

May 23, 2025 - MLB

Milwaukee Brewers
5 :  6
Pittsburgh Pirates

May 22, 2025 - MLB

Milwaukee Brewers
8 :  5
Pittsburgh Pirates

May 21, 2025 - MLB

Cincinnati Reds
1 :  3
Pittsburgh Pirates

May 20, 2025 - MLB

Cincinnati Reds
0 :  1
Pittsburgh Pirates
L L L W W L
Victories

2/6 (33%)

Defeats

4/6 (67%)

May 30, 2025 - MLB

Pittsburgh Pirates
2 :  3
San Diego Padres

May 28, 2025 - MLB

Pittsburgh Pirates
10 :  1
Arizona Diamondbacks

May 27, 2025 - MLB

Pittsburgh Pirates
9 :  6
Arizona Diamondbacks

May 26, 2025 - MLB

Pittsburgh Pirates
0 :  5
Arizona Diamondbacks

May 18, 2025 - MLB

Pittsburgh Pirates
0 :  1
Philadelphia Phillies

May 17, 2025 - MLB

Pittsburgh Pirates
2 :  5
Philadelphia Phillies
San Diego Padres
San Diego Padres Latest matches
L W W W L W
Victories

4/6 (67%)

Defeats

2/6 (33%)

May 30, 2025 - MLB

Pittsburgh Pirates
2 :  3
San Diego Padres

May 28, 2025 - MLB

Miami Marlins
10 :  8
San Diego Padres

May 27, 2025 - MLB

Miami Marlins
6 :  8
San Diego Padres

May 26, 2025 - MLB

Miami Marlins
3 :  4
San Diego Padres

May 25, 2025 - MLB

San Diego Padres
5 :  3
Atlanta Braves

May 24, 2025 - MLB

San Diego Padres
1 :  7
Atlanta Braves
L L W L W W
Victories

3/6 (50%)

Defeats

3/6 (50%)

May 30, 2025 - MLB

Pittsburgh Pirates
2 :  3
San Diego Padres

May 28, 2025 - MLB

Miami Marlins
10 :  8
San Diego Padres

May 27, 2025 - MLB

Miami Marlins
6 :  8
San Diego Padres

May 26, 2025 - MLB

Miami Marlins
3 :  4
San Diego Padres

May 18, 2025 - MLB

Seattle Mariners
6 :  1
San Diego Padres

May 17, 2025 - MLB

Seattle Mariners
4 :  1
San Diego Padres
L L L W L W
Victories

2/6 (33%)

Defeats

4/6 (67%)

May 25, 2025 - MLB

San Diego Padres
5 :  3
Atlanta Braves

May 24, 2025 - MLB

San Diego Padres
1 :  7
Atlanta Braves

May 23, 2025 - MLB

San Diego Padres
2 :  1
Atlanta Braves

May 22, 2025 - MLB

San Diego Padres
6 :  7
Toronto Blue Jays

May 21, 2025 - MLB

San Diego Padres
0 :  14
Toronto Blue Jays

May 20, 2025 - MLB

San Diego Padres
0 :  3
Toronto Blue Jays

Pittsburgh Pirates against San Diego Padres : Head to Head (H2H)

Pittsburgh Pirates

0 %

San Diego Padres

100 %

May 30, 2025 - MLB

Pittsburgh Pirates
2 :  3
San Diego Padres

May 4, 2025 - MLB

San Diego Padres
4 :  0
Pittsburgh Pirates

May 3, 2025 - MLB

San Diego Padres
2 :  1
Pittsburgh Pirates

May 2, 2025 - MLB

San Diego Padres
9 :  4
Pittsburgh Pirates

Aug 14, 2024 - MLB

Pittsburgh Pirates
2 :  8
San Diego Padres

Aug 13, 2024 - MLB

Pittsburgh Pirates
0 :  3
San Diego Padres

Pittsburgh Pirates - San Diego Padres Key Points

  1. San Diego is 4-1 SU in its last 5 games.
  2. San Diego is 13-3 SU in its last 16 games against an opponent in the National League.
  3. Pittsburgh is 0-10 SU in its last 10 games against San Diego.
  4. Pittsburgh is 3-12 SU in its last 15 games on the road.
Up to $250 to bet on Pittsburgh Pirates - San Diego Padres! 

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Our Pittsburgh Pirates vs San Diego Padres Prediction

Why you should bet on the Padres to win: San Diego is 4-1 SU in its last five games and 10-0 in their previous 10 head-to-head meetings with the Pirates. They have also managed to cover the spread in these meetings six times. Dylan Cease has been on a slump as of late, but I expect him to bounce back against the Pirates, whom he has tormented in his last three appearances against the team. Cease sports a 1.30 ERA and 4.0 strikeouts per game in his last three starts vs. the Pirates. Pirates starter Bailey Falter has posted a 0.80 ERA over his last 5 starts, but lost his 2 games against the team.

Our betting prediction for the San Diego Padres vs. Pittsburgh Pirates: Padres -1.5 Runs.

Prediction:

 

Pirates -1.5 Runs

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All tips are fully researched and given in good faith, but profits cannot be guaranteed.

Pittsburgh Pirates vs San Diego Padres Picks
Up to $250 to bet on Pittsburgh Pirates - San Diego Padres! 

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