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by Lou Aguila in MLB Picks
The Pittsburgh Pirates will go for their third straight win with Mitch Keller taking the mound in Friday’s series opener against the San Diego Padres at Petco Park.
The Pirates have won 3 of their last 5 games, including the previous two games of their series against the Arizona Diamondbacks. After being held scoreless in the first game, Pittsburgh responded with 19 runs between Games 2 and 3 and demonstrated a near-flawless pitching performance in a 10-1 win in Game 3. Paul Skenes shut down the D-Backs offense over 6.2 innings, while the bullpen yielded only one earned run.
The Miami Marlins snapped the Padres’ three-game win streak in the series finale, 8-10. San Diego could no longer outscore the Marlins in the final game of their series as the decision to start relief pitcher Jason Adam backfired, surrendering two earned runs in 0.2 innings.
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Pittsburgh Pirates vs San Diego Padres Form
Table
| Teams | % | P | W | L |
|---|---|---|---|---|
|
7
|
0.582 | 55 | 32 | 23 |
|
28
|
0.362 | 58 | 21 | 37 |
Pittsburgh Pirates and San Diego Padres Latest Matches
4/6 (67%)
2/6 (33%)
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4/6 (67%)
2/6 (33%)
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2/6 (33%)
4/6 (67%)
May 28, 2025 - MLB
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4/6 (67%)
2/6 (33%)
May 28, 2025 - MLB
May 27, 2025 - MLB
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May 23, 2025 - MLB
2/6 (33%)
4/6 (67%)
May 28, 2025 - MLB
May 27, 2025 - MLB
May 26, 2025 - MLB
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May 17, 2025 - MLB
May 16, 2025 - MLB
2/6 (33%)
4/6 (67%)
May 25, 2025 - MLB
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Pittsburgh Pirates against San Diego Padres : Head to Head (H2H)
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Pittsburgh Pirates - San Diego Padres Key Points
- San Diego is 4-8 SU in its last 12 games.
- San Diego is 16-4 SU in its last 20 games against an opponent in the National League.
- Pittsburgh is 6-3 SU in its last 9 games.
- Pittsburgh is 0-9 SU in its last 9 games against San Diego.
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Our Pittsburgh Pirates vs San Diego Padres Prediction
Why you should bet on the Pirates to win: Mitch Keller allowed one earned run in each of his last two starts. With the Pittsburgh offense experiencing a surge over the past few days (5.2 runs per game over the last 5 games), Keller should have extra motivation to pitch well, knowing he will have enough run support to secure a win at the end of his stint. He will duel against Nick Pivetta, who surrendered one earned run over six innings in back-to-back starts vs. the Mariners and the Braves. However, Pivetta faces pressure to perform well since the Braves’ starters have given up a 7.50 ERA over the last five games.
Our betting prediction for the Pittsburgh Pirates vs. San Diego Padres: the Pirates will win
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All tips are fully researched and given in good faith, but profits cannot be guaranteed.
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