Pittsburgh Pirates vs Baltimore Orioles Prediction & Picks - MLB

Prediction published on 9/9/25, 3:06 PM  by Lou Aguila in MLB Picks

The Baltimore Orioles look to maintain their winning form as they play host to the Pittsburgh Pirates for a three-game series starting on Tuesday at Oriole Park.

The Pirates, who have won three of their last four meetings with the Orioles, will enter the series finale as an enticing +129 underdog option on the moneyline.

Current Form:

The Pirates will try to rebound after suffering a three-game sweep at the hands of the Milwaukee Brewers. Pittsburgh only scored a total of five runs while conceding 19 runs to the Brewers across three games. The Pirates’ ERA over the last five games has risen to 4.00, which is slightly higher than the 3.91 ERA they have maintained throughout the season. Moreover, the Pirates’ run production has also dropped to 2.7 runs per game on a .203 batting average over the last five games. The Pirates are averaging a mediocre 3.7 runs per contest in the season.

The Orioles’ win streak ended at five games after losing the final game of their series with the Dodgers, 5-2. Like the 64-80 Pirates, Baltimore is also last in their division with a 66-77 record, though this team has won 6 of their last 7 games, -5 of which at the expense of the top-2 teams in the NL West, the Dodgers and the Padres. Over the last five games, the Orioles have averaged a modest 4.3 runs per game but posted an elite 3.00 ERA and a 1.24 WHIP.