Pittsburgh Panthers vs Florida State Seminoles Prediction & Picks - NCAA

USA - NCAA

Pittsburgh Panthers
10/11/25 12:00
Florida State Seminoles

Prediction:

 

Florida State -10

-110
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 by Dan Angell in NCAA Picks

Pittsburgh goes down to Florida State in a game between two teams looking to confirm whether they’re really contenders in the ACC. After an encouraging 3-0 start, Florida State has now dropped two straight games and looks like it’s still got some work to do before getting back up the hill.

The Seminoles are better than they were a season ago, but they only have one impressive win out of three. Granted, it’s a heck of a win against Alabama and better than anything on Pittsburgh’s resume, but it’s now been over a month since that game. If Florida State is going to make a run at a quality bowl game, it must establish itself here as a top ACC team, and that means making a statement against a mid-level squad.

Pittsburgh Panthers vs Florida State Seminoles Form

Table

Teams % P W D L
4
Pittsburgh Panthers
Pittsburgh Panthers
0.75 4 3 0 1
17
Florida State Seminoles
Florida State Seminoles
0 4 0 0 4

Pittsburgh Panthers and Florida State Seminoles Latest Matches

Pittsburgh Panthers
Pittsburgh Panthers Latest matches
L W W L L W
Victories

3/6 (50%)

Draw

0/6 (0%)

Defeats

3/6 (50%)

Oct 4, 2025 - NCAA

Boston College Eagles
7 :  48
Pittsburgh Panthers

Sep 27, 2025 - NCAA

Louisville Cardinals
34 :  27
Pittsburgh Panthers

Sep 13, 2025 - NCAA

Pittsburgh Panthers
24 :  31
West Virginia Mountaineers

Sep 6, 2025 - NCAA

Central Michigan Chippewas
17 :  45
Pittsburgh Panthers

Aug 30, 2025 - NCAA

Duquesne Dukes
9 :  61
Pittsburgh Panthers

Dec 26, 2024 - NCAA Division I, FBS, Playoffs

Pittsburgh Panthers
46 :  48
Toledo Rockets
L L W W L W
Victories

3/6 (50%)

Draw

0/6 (0%)

Defeats

3/6 (50%)

Oct 4, 2025 - NCAA

Boston College Eagles
7 :  48
Pittsburgh Panthers

Sep 27, 2025 - NCAA

Louisville Cardinals
34 :  27
Pittsburgh Panthers

Sep 6, 2025 - NCAA

Central Michigan Chippewas
17 :  45
Pittsburgh Panthers

Aug 30, 2025 - NCAA

Duquesne Dukes
9 :  61
Pittsburgh Panthers

Nov 16, 2024 - NCAA

Clemson Tigers
24 :  20
Pittsburgh Panthers

Nov 9, 2024 - NCAA

Virginia Cavaliers
24 :  19
Pittsburgh Panthers
W L L L L L
Victories

0/5 (0%)

Draw

0/5 (0%)

Defeats

5/5 (100%)

Sep 13, 2025 - NCAA

Pittsburgh Panthers
24 :  31
West Virginia Mountaineers

Dec 26, 2024 - NCAA Division I, FBS, Playoffs

Pittsburgh Panthers
46 :  48
Toledo Rockets

Nov 30, 2024 - NCAA

Pittsburgh Panthers
23 :  34
Boston College Eagles

Nov 23, 2024 - NCAA

Pittsburgh Panthers
9 :  37
Louisville Cardinals

Nov 2, 2024 - NCAA

Pittsburgh Panthers
25 :  48
SMU Mustangs
Florida State Seminoles
Florida State Seminoles Latest matches
L W W W L L
Victories

3/6 (50%)

Draw

0/6 (0%)

Defeats

3/6 (50%)

Oct 4, 2025 - NCAA

Miami (FL) Hurricanes
28 :  22
Florida State Seminoles

Sep 26, 2025 - NCAA

Florida State Seminoles
38 :  46
Virginia Cavaliers

Sep 20, 2025 - NCAA

Kent State Golden Flashes
10 :  66
Florida State Seminoles

Sep 6, 2025 - NCAA

East Texas AM Lions
3 :  77
Florida State Seminoles

Aug 30, 2025 - NCAA

Alabama Crimson Tide
17 :  31
Florida State Seminoles

Nov 30, 2024 - NCAA

Florida Gators
31 :  11
Florida State Seminoles
W L W W W L
Victories

4/6 (67%)

Draw

0/6 (0%)

Defeats

2/6 (33%)

Oct 4, 2025 - NCAA

Miami (FL) Hurricanes
28 :  22
Florida State Seminoles

Sep 20, 2025 - NCAA

Kent State Golden Flashes
10 :  66
Florida State Seminoles

Sep 6, 2025 - NCAA

East Texas AM Lions
3 :  77
Florida State Seminoles

Aug 30, 2025 - NCAA

Alabama Crimson Tide
17 :  31
Florida State Seminoles

Nov 30, 2024 - NCAA

Florida Gators
31 :  11
Florida State Seminoles

Nov 23, 2024 - NCAA

Charleston Southern Buccaneers
7 :  41
Florida State Seminoles
L L L L L
Victories

0/5 (0%)

Draw

0/5 (0%)

Defeats

5/5 (100%)

Sep 26, 2025 - NCAA

Florida State Seminoles
38 :  46
Virginia Cavaliers

Nov 9, 2024 - NCAA

Florida State Seminoles
3 :  52
Notre Dame Fighting Irish

Oct 26, 2024 - NCAA

Florida State Seminoles
14 :  36
Miami (FL) Hurricanes

Oct 18, 2024 - NCAA

Florida State Seminoles
16 :  23
Duke Blue Devils

Aug 24, 2024 - NCAA

Florida State Seminoles
21 :  24
Georgia Tech Yellow Jackets

Pittsburgh Panthers - Florida State Seminoles Key Points

  1. Florida State is 0-9 SU in its past nine ACC games.
  2. The visiting team has won the past three meetings.
  3. Pittsburgh has allowed at least 30 points in four straight games away from Acrisure Stadium.
  4. Pittsburgh is 0-3 ATS in its past three games as an underdog.

Our Pittsburgh Panthers vs Florida State Seminoles Prediction

Was Mason Heintschel the answer for Pittsburgh, or did that have more to do with playing Boston College? Unlike the Seminoles, the Eagles’ winless record in the ACC is legitimate, and Pitt absolutely dismantled BC at home. But this is also the same Pitt team that lost at West Virginia, and the Mountaineers have been getting boatraced weekly in the Big 12.

More likely, Heintschel’s success had to do with the quality — or lack thereof — of his team’s opposition. The Panthers still have not proven they can beat a quality team, especially on the road. They were able to play with Louisville, but that happened because the Cardinals had a nightmarish first quarter where they spotted Pitt 17 points. The Panthers won’t be as lucky against the Seminoles. Our prediction for Pittsburgh vs. Florida State is Florida State -10.

Prediction:

 

Florida State -10

-110
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Pittsburgh Panthers vs Florida State Seminoles Picks