Philadelphia Phillies vs Los Angeles Dodgers Prediction & Picks - MLB

Prediction published on 9/17/25, 6:54 PM  by Lou Aguila in MLB Picks

The Los Angeles Dodgers will try to prevent a sweep at the hands of the Philadelphia Phillies in Wednesday’s series finale at Dodger Stadium.

The Dodgers are listed as -150 favorites with Blake Snell starting for the first time since throwing six scoreless innings in the Dodgers’ 9-0 win over Colorado last September 10.

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The Dodgers have now lost their last three meetings against the Phillies following Tuesday’s 6-9 loss. Shohei Ohtani logged 5 hitless innings, but once again, the relief pitchers blew a 4-0 lead by allowing the Phillies to score nine runs in the final four innings. Los Angeles still holds the No.1 spot in the NL West with an 84-67 record, though they can no longer afford to lose more games in the coming days because the Padres are only 2.0 games behind them.

The Phillies have improved their head-to-head record against the Dodgers to 8-2 in their last 10 games. Out of these 8 wins, Philadelphia managed to beat the Dodgers by at least two runs four times. The Phillies have already secured the NL East title with a 91-61 record, 12.5 games ahead of the closest trailers, the 78-73 New York Mets.